Journal of Applied Biomaterials & Functional Materials,
Journal Year:
2024,
Volume and Issue:
22
Published: Jan. 1, 2024
Objectives:
To
review
the
progress
of
Platelet
Rich
Fibrin
(PRF)
as
a
biomaterial
in
dentistry
and
to
highlight
its
promising
application
safe
biocompatible
autologous
platelet
concentrate.
Publications
were
searched
GeenMedical,
X-mol,
GoogleScholar,
PubMed
from
October
2024
with
no
language
restrictions.
The
literature
was
for
relevant
databases
journals
on
use
PRFs
up
2024,
inclusion
criteria
included
randomized
controlled
trials,
clinical
case
series,
systematic
reviews.
Conclusion:
PRF
is
second-generation
concentrate
that
sourced
oneself,
has
fewer
adverse
effects,
simple
prepare.
These
materials
include
growth
factors
fibrin
scaffolds,
which
are
extensively
utilized
regenerative
medicine.
By
outlining
PRF,
we
found
good
results
can
be
achieved
when
used
treat
these
conditions.
Clinical
significance:
widespread,
particularly
periodontal
soft
hard
tissue
regeneration,
oral
lichen
planus,
pulpal
regeneration.
This
article
reviews
background,
classification,
preparation
methods
PRFs,
along
their
dental
applications.
We
anticipate
further
research
various
derivatives
future,
will
significantly
improve
utilization
applications
offer
fresh
insights
diagnosing
treating
diseases.
Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 14, 2025
Abstract
Severe
bone
and
cartilage
defects
caused
by
trauma
are
challenging
to
treat,
often
resulting
in
poor
outcomes.
An
endogenous
electric
field
(EnEF)
is
crucial
for
regeneration,
making
electrical
materials
a
promising
therapy.
This
review
provides
comprehensive
overview
of
the
role
bioelectric
signals
cells,
alongside
recent
advancements
biomaterials,
with
particular
emphasis
on
nanogenerators,
piezoelectric
materials,
triboelectric
scaffolds,
zwitterionic
hydrogels.
It
further
investigates
impact
these
biomaterials
as
well
applications
both
exogenous
stimulation
(ES)
mechanisms
underlying
ES‐induced
cellular
molecular
responses.
Finally,
underscores
future
directions
ES
systems
tissue
engineering,
emphasizing
critical
importance
integrating
structural
integrity,
mechanical
properties,
signal
delivery
into
intelligent
implantable
scaffolds.
Journal of Functional Biomaterials,
Journal Year:
2024,
Volume and Issue:
15(7), P. 178 - 178
Published: June 28, 2024
Zinc
is
known
for
its
role
in
enhancing
bone
metabolism,
cell
proliferation,
and
tissue
regeneration.
Several
studies
proposed
the
incorporation
of
zinc
into
hydroxyapatite
(HA)
to
produce
biomaterials
(ZnHA)
that
stimulate
accelerate
healing.
This
systematic
review
aimed
understand
physicochemical
characteristics
zinc-doped
HA-based
evidence
their
biological
effects
on
osteoblastic
cells.
A
comprehensive
literature
search
was
conducted
from
2022
2024,
covering
all
years
publications,
three
databases
(Web
Science,
PUBMED,
Scopus),
retrieving
609
entries,
with
36
articles
included
analysis
according
selection
criteria.
The
selected
provided
data
material’s
properties,
methods
incorporation,
ZnHA
production
typically
involves
wet
chemical
synthesis
HA
precursors,
followed
by
deposition
substrates
using
processes
such
as
liquid
precursor
plasma
spraying
(LPPS).
Characterization
techniques
confirmed
successful
lattice.
findings
indicated
at
low
concentrations
non-cytotoxic
beneficial
found
adhesion,
osteogenic
factors,
thereby
promoting
vitro
mineralization.
However,
optimal
concentration
desired
varied
across
studies,
making
it
challenging
establish
a
standardized
concentration.
materials
are
biocompatible
enhance
osteoblast
proliferation
differentiation.
mechanisms
release
ideal
regeneration
require
further
investigation.
Standardizing
these
parameters
essential
effective
clinical
application
ZnHA.
Journal of Personalized Medicine,
Journal Year:
2024,
Volume and Issue:
14(8), P. 809 - 809
Published: July 30, 2024
3D-printing
technology
has
revolutionized
spinal
implant
manufacturing,
particularly
in
developing
personalized
and
custom-fit
titanium
interbody
fusion
cages.
These
cages
are
pivotal
supporting
inter-vertebral
stability,
promoting
bone
growth,
restoring
alignment.
This
article
reviews
the
latest
advancements
3D-printed
cages,
emphasizing
their
relevance
modern
surgical
spine
care
protocols
applied
to
common
clinical
scenarios.
Furthermore,
authors
review
various
printing
post-printing
processing
technologies
discuss
how
engineering
design
deployed
tailor
each
type
of
its
patient-specific
application,
highlighting
anatomical
biomechanical
considerations
impact
development
manufacturing
processes
achieve
optimum
osteoinductive
osteoconductive
properties.
The
further
examines
benefits
3D
printing,
such
as
customizable
geometry
porosity,
that
enhance
osteointegration
mechanical
compatibility,
offering
a
leap
forward
solutions.
comparative
analysis
provided
by
underscores
unique
challenges
solutions
designing
cervical,
lumbar
implants,
including
load-bearing
requirements
bioactivity
with
surrounding
bony
tissue
promote
cell
attachment.
Additionally,
outcomes
associated
these
implications
improvements
precision
on
patient
outcomes.
Lastly,
they
address
strategies
overcome
implementation
healthcare
facilities,
which
often
resist
new
acquisitions
due
perceived
cost
overruns
preconceived
notions
hinder
potential
savings
providing
customized
implants
for
lower
complication
revision
rates.
comprehensive
aims
provide
insights
into
made,
explain
quality
standards,
may
care.
Journal of Biomaterials Science Polymer Edition,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 27
Published: Feb. 7, 2025
In
orthopaedic
clinical
applications,
creating
biocomposite
bone
substitutes
to
take
the
place
of
autologous
transplants
is
still
difficult.
Studies
have
demonstrated
for
decades
that
poly
(lactic-co-glycolic
acid)
[PLGA],
a
common
polymer,
has
many
benefits
make
it
strong
contender
replacement.
These
include
biodegradability,
good
mechanical
qualities,
and
ability
induce
new
production.
Although
calcium-based
materials
are
frequently
used
as
fillers
in
implantation,
efficiency
ceramic
containing
calcium
may
be
hampered
by
number
issues,
including
low
microporosity
quick
rates
degradation.
order
overcome
these
obstacles,
scientists
investigating
ways
improve
implant
performance
combining
PLGA
with
other
materials,
especially
terms
encouraging
improved
connections
nearby
cells.
An
overview
chemical
properties
different
PLGA-based
scaffold
composites,
well
drawbacks
PLGA-Calcium
implants
tissue
engineering
goals
this
review.
It
also
highlights
possible
advantages
consequences
using
3D
printing
technology
outcomes.
Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 25, 2025
Abstract
The
potential
applications
of
rare
earth
elements
(REEs)
in
biomedical
fields
have
been
intensively
investigated.
Numerous
studies
shown
that
doping
biomaterials
with
REEs
can
enhance
their
properties.
Gadolinium
(Gd)
is
a
biocompatible
REE
holds
promise
applications.
This
review
examines
the
use
Gd‐doped
osteogenic,
antimicrobial,
anticancer
applications,
and
bioimaging
bioprobes,
as
reported
literature
until
December
2024.
included
demonstrate
Gd‐containing
promote
osteogenesis,
antimicrobial
properties,
perform
well
bioimaging.
Taken
together,
they
point
to
considerable
thus
avenues
for
future
research.
