Zero-Dimensional Carbon Nanomaterials for Fluorescent Sensing and Imaging

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(18), P. 11047 - 11136

Published: Sept. 7, 2023

Advances in nanotechnology and nanomaterials have attracted considerable interest play key roles scientific innovations diverse fields. In particular, increased attention has been focused on carbon-based exhibiting extended structures unique properties. Among these materials, zero-dimensional structures, including fullerenes, carbon nano-onions, nanodiamonds, dots, possess excellent bioaffinities superior fluorescence properties that make suitable for application to environmental biological sensing, imaging, therapeutics. This review provides a systematic overview of the classification structural properties, design principles preparation methods, optical sensing applications nanomaterials. Recent interesting breakthroughs sensitive selective imaging heavy metal pollutants, hazardous substances, bioactive molecules as well information encryption, super-resolution photoacoustic phototherapy nanomedicine delivery are main focus this review. Finally, future challenges prospects materials highlighted envisaged. presents comprehensive basis directions designing, developing, applying fascinating fluorescent sensors fabricated based specific requirements numerous research

Language: Английский

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Lignocellulosic Biomass‐Based Carbon Dots: Synthesis Processes, Properties, and Applications

Small, Journal Year: 2023, Volume and Issue: 19(48)

Published: Aug. 3, 2023

Carbon dots (CDs), a new type of carbon-based fluorescent nanomaterial, have attracted widespread attention because their numerous excellent properties. Lignocellulosic biomass is the most abundant renewable natural resource and possesses broad potential to manufacture different composite smart materials. Numerous studies explored using components (such as cellulose, hemicellulose, lignin) in lignocellulosic produce CDs. There are few papers systemically aiming review state-of-the-art works related biomass-derived In this review, significant advances synthesis processes, formation mechanisms, structural characteristics, optical properties, applications biomass-based CDs such cellulose-based CDs, hemicellulose-based lignin-based latest research reviewed. addition, future directions on improvement technology raw materials enhance properties proposed. This will serve road map for scientists engaged exploring more science fields achieve highest material performance goals

Language: Английский

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Portable Smartphone Platform Based on Aggregation-Induced Enhanced Emission Carbon Dots for Ratiometric Quantitative Sensing of Fluoride Ions

ACS Sensors, Journal Year: 2023, Volume and Issue: 8(2), P. 884 - 892

Published: Jan. 19, 2023

The development of an instrument-free, on-site, real-time, sensitive, and visualized fluoride-ion (F–) content rapid detection strategy is crucial to ensuring the health population. Smart microdevices that are portable, directly read, easy operate have recently attracted much attention. Herein, a ratiometric fluorescent probe (AA-CDs@[Ru(bpy)3]2+)-based smartphone sensing platform was developed for F–. red ruthenium bipyridine [Ru(bpy)3]2+ molecule chosen as reference signal, carbon dots (AA-CDs) with Al3+ aggregation-induced enhanced emission (AIE) were designed response signal. fluorescence changed continuously from cyan in different concentrations F–, red–green–blue (RGB) channel values image extracted through color recognition application (APP). There linear relationship between blue–red (B/R) ratio F– concentration, limit (LOD) 1.53 μM, far below allowable drinking water prescribed by World Health Organization. rapidly detected on-site satisfactory repeatability relative standard deviation using several toothpaste samples real sample. features low cost, portability, operation, good stability, selectivity, repeatability, which provides powerful tool visual quantitative smartphone-based microsensing platforms possibly fields environmental protection, diagnosis, food safety assessment.

Language: Английский

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Review on Carbon Dot-Based Fluorescent Detection of Biothiols

Biosensors, Journal Year: 2023, Volume and Issue: 13(3), P. 335 - 335

Published: March 2, 2023

Biothiols, such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH), play a vital role in gene expression, maintaining redox homeostasis, reducing damages caused by free radicals/toxins, etc. Likewise, abnormal levels of biothiols can lead to severe diseases, Alzheimer’s disease (AD), neurotoxicity, hair depigmentation, liver/skin damage, To quantify the biological system, numerous low-toxic probes, fluorescent quantum dots, emissive organic composited nanomaterials, etc., have been reported with real-time applications. Among these carbon-dots (CDs) become attractive for quantification because advantages easy synthesis, nano-size, crystalline properties, low-toxicity, applicability. A CDs-based assay be achieved “Turn-On” “Turn-Off” responses via direct binding, metal complex-mediated detection, composite enhanced interaction, reaction-based reports, so forth. date, availability review focused on detection information recent trends, mechanistic aspects, linear ranges, LODs, real applications is lacking, which allows us deliver this comprehensive review. This delivers valuable carbon-dots-based assays, underlying mechanism, their applications, probe/CDs selection, sensory requirement, merits, limitations, future scopes.

Language: Английский

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Orange-Emissive Carbon Dots with High Photostability for Mitochondrial Dynamics Tracking in Living Cells

ACS Sensors, Journal Year: 2023, Volume and Issue: 8(3), P. 1161 - 1172

Published: Feb. 16, 2023

Mitochondria play significant roles in maintaining a stable internal environment for cell metabolism. Hence, real-time monitoring of the dynamics mitochondria is essential further understanding mitochondria-related diseases. Fluorescent probes provide powerful tools visualizing dynamic processes. However, most mitochondria-targeted are derived from organic molecules with poor photostability, making long-term challenging. Herein, we design novel probe based on carbon dots high performance tracking. Considering that targeting ability CDs related to surface functional groups, which generally determined by reaction precursors, successfully constructed O-CDs emission at 565 nm through solvothermal treatment m-diethylaminophenol. The bright quantum yield 12.61%, mitochondria-targeting ability, and good stability. possess (12.61%), specific outstanding optical Owing abundant hydroxyl ammonium cations surface, showed obvious accumulation colocalization coefficient up 0.90 remained steady even after fixation. Besides, compatibility photostability under various interruptions or long-time irradiation. Therefore, preferable tracking mitochondrial behavior live cells. We first observed fission fusion behaviors HeLa cells, then, size, morphology, distribution physiological pathological conditions were clearly recorded. More importantly, different interactions between lipid droplets during apoptosis mitophagy This study provides potential tool exploring other organelles, promoting research

Language: Английский

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Förster Resonance Energy Transfer between Multicolor Emissive N-Doped Carbon Quantum Dots and Gold Nanorods for the Detection of H₂O₂, Glucose, Glutathione, and Acetylcholinesterase

ACS Applied Nano Materials, Journal Year: 2023, Volume and Issue: 6(9), P. 8046 - 8058

Published: April 27, 2023

Multicolor emissive nitrogen-doped carbon quantum dots (CQDs) were synthesized by the hydrothermal method and characterized using spectroscopic electron microscopic techniques. Förster resonance energy transfer (FRET) between CQDs gold nanorods (AuNRs) has been investigated that occurs due to distinctive overlap of transverse longitudinal bands AuNRs with fluorescence (FL) spectra CQDs. Significant FL quenching (turn-off) their recovery (turn-on) have observed etching end-to-end assemblies lead detection biomolecules like H2O2, glucose, glutathione (GSH), acetylcholinesterase (AChE). The redox reaction Au(0) H2O2 results in decomposition give Au(I) ions, thereby inducing (turn-on). interruption FRET phenomenon production from glucose oxidase presence a thiol-containing compound acetylthiocholine AChE enzyme causes CQDs, respectively. Moreover, assembly leads disruption, turn-on signals found be measures GSH. In comparison UV–visible approach, measurements through process are more sensitive under same conditions. practical applicability proposed sensing system verified human plasma samples.

Language: Английский

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See the Unseen: Red‐Emissive Carbon Dots for Visualizing the Nucleolar Structures in Two Model Animals and In Vivo Drug Toxicity

Small, Journal Year: 2023, Volume and Issue: 19(31)

Published: Jan. 12, 2023

Abstract Nucleolus, which participates in many crucial cellular activities, is an ideal target for evaluating the state of a cell or organism. Here, bright red‐emissive carbon dots (termed CPCDs) with excitation‐independent/polarity‐dependent fluorescence emission are synthesized by one‐step hydrothermal reaction between congo red and p ‐phenylenediamine. The CPCDs can achieve wash‐free, real‐time, long‐term, high‐quality nucleolus imaging live cells, as well vivo two common model animals—zebrafish Caenorhabditis elegans ( C . ). Strikingly, realize organs/flowing blood cells zebrafish at level first time, superb suggests that germ spermatheca probably have no intact nuclei. These previously unachieved results cells/tissues/organs may guide zebrafish‐related studies benefit research development. More importantly, novel strategy based on toxicity evaluation materials/drugs (e.g., Ag + ), visualize otherwise unseen injuries zebrafish, developed. In conclusion, represent robust tool visualizing structures dynamic behaviors , find important applications biology toxicology.

Language: Английский

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Highly efficient regulation strategy of fluorescence emission wavelength via designing the structure of carbon dots

Advanced Composites and Hybrid Materials, Journal Year: 2023, Volume and Issue: 6(2)

Published: March 15, 2023

Language: Английский

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The Emerging Star of Carbon Luminescent Materials: Exploring the Mysteries of the Nanolight of Carbon Dots for Optoelectronic Applications

Small, Journal Year: 2024, Volume and Issue: 20(31)

Published: March 10, 2024

Carbon dots (CDs), a class of carbon-based nanomaterials with dimensions less than 10 nm, have attracted significant interest since their discovery. They possess numerous excellent properties, such as tunability photoluminescence, environmental friendliness, low cost, and multifunctional applications. Recently, large number reviews emerged that provide overviews synthesis, applications, composite functionalization. The application CDs in the field optoelectronics has also seen unprecedented development due to optical but them this are relatively rare. With idea deepening broadening understanding applications optoelectronics, review for first time provides detailed summary luminescent solar concentrators (LSCs), light-emitting diodes (LEDs), cells, photodetectors. In addition, definition, categories, synthesis methods briefly introduced. It is hoped can bring scholars more deeper optoelectronic further promote practical CDs.

Language: Английский

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Bridging biological and food monitoring: A colorimetric and fluorescent dual-mode sensor based on N-doped carbon dots for detection of pH and histamine

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 470, P. 134271 - 134271

Published: April 10, 2024

Language: Английский

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