Optically Active Derivatives with a Stereogenic Sulfur Center: Synthesis and Applications DOI
D. Krasowska,

Agata. J. Pacuła-miszewska,

Jacek Ścianowski

et al.

The Royal Society of Chemistry eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 225 - 240

Published: Feb. 15, 2023

This chapter describes briefly optically active sulfur-containing derivatives whose chirality results from the presence of a stereogenic sulfur atom with different valency and coordination numbers. Thus, it updates more or less rich literature reports on most common approaches that have made possible to isolate them as forms. Their recent synthetic applications are also illustrated.

Language: Английский

Advances in photochemical and electrochemical incorporation of sulfur dioxide for the synthesis of value-added compounds DOI Creative Commons

Stephan P. Blum,

Kamil Hofman,

Georg Manolikakes

et al.

Chemical Communications, Journal Year: 2021, Volume and Issue: 57(67), P. 8236 - 8249

Published: Jan. 1, 2021

Photosynthesis and electrosynthesis enable the “green” upcycling of SO 2 to value-added products.

Language: Английский

Citations

82
Electrochemical multi-component reaction of potassium metabisulfite with alkenes and alcohols enabling synthesis of sulfonate esters DOI
Jiang Liu, Jingcheng Xu, Haibo Mei

et al.

Green Chemistry, Journal Year: 2022, Volume and Issue: 24(16), P. 6113 - 6118

Published: Jan. 1, 2022

An electrochemical sulfur dioxide insertion reaction of alkenes and alcohols with potassium metabisulfite as the surrogate has been developed, which provides a green efficient method for preparation sulfonate esters.

Language: Английский

Citations

29
Sulfur stereogenic centers in transition-metal-catalyzed asymmetric C–H functionalization: generation and utilization DOI Creative Commons
Wentan Liu, Jie Ke, Chuan He

et al.

Chemical Science, Journal Year: 2021, Volume and Issue: 12(33), P. 10972 - 10984

Published: Jan. 1, 2021

This perspective highlights sulfur functional groups enabled enantioselective C–H functionalization for the construction of stereogenic centers, and utilization chiral sulfoxide to realize stereoselective functionalization.

Language: Английский

Citations

34
Recent Developments in Selenylation and Thiolation of Alkenes via Three‐component Reactions DOI

Liguo Lu,

Dayun Huang, Zefeng Wang

et al.

Advanced Synthesis & Catalysis, Journal Year: 2023, Volume and Issue: 365(14), P. 2310 - 2331

Published: June 24, 2023

Abstract Alkenes are valuable feedstocks in organic synthesis. Selenium or sulfur‐containing coumpounds with a neighboring functional group can be easily prepared by direct difunctionalization of alkenes via three‐component reactions. It will reduce the number steps and waste generation, form complicated molecules from simple starting materials. Herein, recent developments (2013–2022) have been summarized two categories: (1) selenylation seleniranium intermediates Se‐centered radicals; (2) thiolation more diverse mechanisms products Reactions electron‐rich arenes, alcohols, water, acids, NaN 3 , amines, KSCN, sulfamides, TMSNCS, TMSN Et N ⋅ 3HF, SOCl 2 HCl, NFSI, t BuONO, pyridinium salts, BuOOH, ArN BF 4 CO CO, O CF SO Cl, R P(O)−H, (RO) P(O)SH, P(O)OH et al discussed. We hope this review do help for future research area.

Language: Английский

Citations

15
Nanocatalyzed Organic Transformations for Synthesis of Drug-Like Small Molecules with Privileged Heterocycles DOI

Sakshi Pathak,

Kanchan Verma,

Gargi Pathak

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Gold Nanoparticle-Catalyzed Multicomponent Reactions DOI
Hossein Yazdani, Seyyed Emad Hooshmand, Rajender S. Varma

et al.

ACS Sustainable Chemistry & Engineering, Journal Year: 2021, Volume and Issue: 9(49), P. 16556 - 16569

Published: Dec. 3, 2021

Nanotechnology and nanoscience hold great promise for many multidisciplinary applications, including catalysis where gold nanoparticles (GNPs) are considered "safer environmentally benign" on account of the fact that they relatively nontoxic efficient pivotal applications in natural-product synthesis, organic reactions, pharmaceutical industry, medicinal chemistry. Since physicochemical characteristics GNPs pertain to their shape, size, composition, surface modification, these features contribute reactivity toxicity nanomaterials catalytic systems. Multicomponent reactions (MCRs) lead expeditious synthesis biologically active molecules ingredients (APIs) with atom economy high efficiency, as well a low E-factor, can be performed one-pot operations deploying three or more reactants. Thus, robust catalysts MCRs comprise an effective synthetic route ideal combination augmentation greener sustainable methods. Accordingly, cutting-edge examples nanoparticle-catalyzed multicomponent leading diverse range valuable such isoxazolines, propargylamines, 3,4-dihydropyrimidin-2(1H)-ones, pyrans, chromeno[2,3-d]pyrimidins, pyridines, benzodiazepines discussed highlighted.

Language: Английский

Citations

27
An efficient metal-free and catalyst-free C–S/C–O bond-formation strategy: synthesis of pyrazole-conjugated thioamides and amides DOI Creative Commons
Shubham Sharma, Dharmender Singh, Sunit Kumar

et al.

Beilstein Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 19, P. 231 - 244

Published: March 2, 2023

An operationally simple and metal-free approach is described for the synthesis of pyrazole-tethered thioamide amide conjugates. The thioamides were generated by employing a three-component reaction diverse pyrazole C-3/4/5 carbaldehydes, secondary amines, elemental sulfur in single synthetic operation. advantages this developed protocol refer to broad substrate scope, easy perform conditions. Moreover, C-3/5-linked conjugates also synthesized via an oxidative amination carbaldehydes 2-aminopyridines using hydrogen peroxide as oxidant.

Language: Английский

Citations

10
Palladium-Catalyzed Amino-Sulfonylation of Aryl Iodide Derivatives via the Insertion of Sulfur Dioxide: One-Pot Synthesis of Aryl Primary Sulfonamides with Thiourea Dioxides DOI
Yong Li, Kai Cheng,

Panyu Ge

et al.

Synthesis, Journal Year: 2024, Volume and Issue: unknown

Published: June 10, 2024

Abstract A palladium-catalyzed one-pot amino-sulfonylation of aryl iodide derivatives with thiourea dioxide, PdCl2dppf, and added hydroxylamine-O-sulfonic acid is presented. This gave structure diversity to primary sulfonamides features good functional group compatibility, mild reaction conditions, excellent regioselectivity, moderate yields. The robustness potential this method have also been successfully demonstrated by late-stage elaboration gram-scale reaction. approach achieves the divergent construction complex core structures that are prevalent in highly valuable natural products such as Sulpiride, Venetoclax, Furosemide­.

Language: Английский

Citations

3
An efficient and environmentally benign domino protocol for the synthesis of spirodihydropyridines using europium-doped ZnO nanoparticles as recyclable and reusable heterogeneous catalyst DOI
Asha Verma, Surendra Kumar Saini, Lalita Kumari

et al.

Research on Chemical Intermediates, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 24, 2025

Language: Английский

Citations

0
One‐Pot Synthesis of β‐Bromo Sulfones and Vinyl Sulfones via Different Column Chromatography DOI Open Access

Shuyan Lai,

H Adam,

Qingle Zeng

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(9)

Published: March 1, 2025

Abstract An unusual halosulfonylation of olefins, p ‐tosylhydrazones, and NBS without the need for any additional base or catalyst has been successfully discovered via elimination diazo compound intermediate. This reaction produces two classes compounds, namely β‐bromo sulfones vinyl sulfones, with entirely distinct structures under different column chromatography conditions. A free radical‐type mechanism this is proposed based on control experiments HRMS analysis. an easy, eco‐friendly, effective synthetic method to synthesize β‐halo from same system.

Language: Английский

Citations

0