The
access
of
heterocyclic
compounds
via
direct
amination
C-H
bonds
are
vital
interest
because
their
role
in
pharmaceutical
and
natural
products.
combination
molecular
iodine
electricity
activates
benzylic
bond
facilitates
the
process
intramolecular
C-N
formation.
Iodine
works
as
a
mediator
for
formation
activation
distance
through
intermediate
N-I
under
electrochemical
conditions,
so
can
be
called
electrocatalyst.
Under
both
batch
&
flow
electrochemistry
similar
results
were
obtained
cyclization
product
with
77
78%
yields
respectively.
However,
case
annulation
reaction
higher
yield
was
99%
conversion
conditions
using
our
design
home-made
microreactor.
In
transformations,
well
reaction,
no
photocatalyst
used.
Notably,
reactions
work
safe
environmentally
friendly
continuous
products
obtained.
Acta Chimica Sinica,
Journal Year:
2022,
Volume and Issue:
80(8), P. 1115 - 1115
Published: Jan. 1, 2022
Organic
electrochemical
synthesis
has
become
a
useful
and
environmentally
friendly
alternative
to
traditional
organic
been
applied
oxidation,
reduction,
or
redox
neutral
transformation.By
dialing
in
the
electric
current
electrode
potential,
it
is
possible
achieve
some
challenging
transformations
under
mild
reaction
conditions.With
increasing
awareness
of
energy
efficiency
environmental
protection,
attracted
much
attention
recent
years.However,
faces
several
challenges
including
passivation,
limited
types,
difficulty
controlling
reactivity
selectivity,
so
on.This
review
focuses
on
solution
system,
summarizes
efforts
addressing
these
through
direct
electrolysis
indirect
electrolysis.In
electrolysis,
strategies
include
rational
design
reactions,
change
modes
equipment,
merging
technology
with
other
novel
synthetic
technologies.In
terms
compounds
transition
metals
are
mainly
used
as
molecular
electrocatalysts
shuttle
electrons
between
electrodes
substrates
control
affording
chemical
transformations.
Current Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
28(2), P. 105 - 116
Published: Jan. 1, 2024
Abstract:
Sodium
sulfinates
have
been
widely
utilized
as
sulfonyl
radical
precursors
for
preparing
a
diverse
array
of
value-added
sulfur-containing
compounds
(sulfones,
sulfonamides,
sulfonates,
thiosulfonates,
etc.)
through
S-C,
S-N,
S-O
and
S-S
bonds
formation
reactions.
Organic
electrosynthesis
has
become
an
attractive
alternative
to
conventional
methods
redox
reactions
because
it
utilizes
electric
current
instead
chemical
agents.
As
such,
the
electrochemical
generation
radicals
from
sodium
their
applications
in
organic
attracted
much
attention.
In
this
review,
recent
advances
sulfonylation
involving
since
2015
were
reviewed,
along
with
related
reaction
mechanisms.
ACS Catalysis,
Journal Year:
2025,
Volume and Issue:
15(3), P. 1753 - 1770
Published: Jan. 16, 2025
Although
C–H
bond
functionalization
has
been
extensively
studied
since
its
discovery
in
1955,
the
borylation
of
organic
compounds
by
activating
bonds
only
became
popular
valuable
Hartwig
1995
who
considered
a
wider
application
these
transformations
synthetic
chemistry.
For
borylation,
catalytic
activation
this
generally
low-reactivity
can
be
performed
many
ways.
Among
approaches
reported
are
use
and
stoichiometric
reagents,
thermal
activation,
photochemical
suitable
substrates.
Iridium-,
ruthenium-,
rhodium-based
protocols
using
have
played
crucial
role
toward
establishment
area.
Photochemical
though,
scarcely
explored
despite
fact
that
it
represents
comparably
environmentally
benign
protocol
light
as
renewable
energy
source.
In
literature
survey,
we
highlight
recent
developments
from
initial
inception
up
to
latest
advancements.
The Chemical Record,
Journal Year:
2023,
Volume and Issue:
23(10)
Published: May 31, 2023
Abstract
C−H
bond
functionalization
generates
molecular
complexity
in
single‐step
transformation.
However,
the
activation
of
bonds
requires
expensive
metals
or
stoichiometric
amounts
oxidizing/reducing
species.
In
many
cases,
they
often
require
pre‐functionalization
starting
molecules.
Such
pre‐activating
measures
cause
waste
generation
and
their
separation
from
final
product
is
also
troublesome.
such
a
scenario,
reactions
activating
elements
generating
renewable
energy
resources
as
electricity
light
would
be
more
efficient,
green,
cost‐effective.
Further,
incorporation
growing
flow
technology
chemical
transformation
processes
will
accelerate
safer
accesses
valuable
products.
Arenes
&
heteroarenes
are
ubiquitous
pharmaceuticals,
natural
products,
medicinal
compounds,
other
biologically
important
Herein,
we
discussed
enabling
tools
technologies
used
for
recent
arenes
heteroarenes.
ChemElectroChem,
Journal Year:
2023,
Volume and Issue:
10(23)
Published: Oct. 20, 2023
Abstract
Cathodic
reductive
electrolysis
in
organic
transformations
is
used
to
generate
radical
anions.
These
electrochemical
reduction
reactions
are
very
useful
various
carbonyl
groups
transformation
(such
as
aldehydes,
ketones,
esters,
and
amides),
new
bond
formations
well
of
saturated
unsaturated
molecules.
Reductive
electrocarboxylation
access
valuable
chemicals
one
the
important
applications
cathodic
electrolysis.
Herein,
we
review
particularly
taking
place
at
cathode.
We
also
discuss
how
alternative
strategies
such
paired
electrolysis,
photo‐electrolysis,
alternating
current
can
be
overcome
limitations
associated
with
they
will
improve
sustainable
transformations.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(40), P. 7451 - 7456
Published: Oct. 4, 2023
An
electrosynthesis
of
spiro-indolenines
in
batch
and
continuous
flow
was
achieved
through
dearomative
arylation
indoles
with
good
functional
group
compatibility.
User-friendly
undivided
cells
were
used
under
catalyst-
oxidant-free
conditions.
Moreover,
the
use
a
electrolysis
cell
gave
high
daily
productivity
excellent
scale-up
potential
less
supporting
electrolyte
higher
substrate
concentration
