B(C6F5)3‐Catalyzed [2+3]‐Cyclative o,m‐diC‐H Functionalization of Phenols DOI

Jingyan Luo,

Zhou Luo,

Biqi Zhang

et al.

Chemistry - A European Journal, Journal Year: 2023, Volume and Issue: 29(71)

Published: Sept. 28, 2023

Metal-free catalytic C-H functionalization is highly desired for the construction of C-C bonds. We herein report a chemoselective consecutive [2+3]-cyclative simultaneous formation two bonds with polycyclic phenols catalyzed by commercially available and low-cost B(C6 F5 )3 . This system tolerates wide range substrate scope, providing series 2,6,7,8-tetrahydroacenaphthylen-3-ol-type compounds efficiently. Several derivatizations products have also been conducted to show potential application this method in synthesis compounds.

Language: Английский

Metal-Free ortho C–H Borylation of Thiobenzamides DOI

Jianxing Lv,

Yixuan Liang,

Y. OUYANG

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(18), P. 3709 - 3714

Published: May 1, 2024

A BBr3-mediated S-directed ortho C–H borylation of thiobenzamides was developed. variety ortho-borylated were obtained in moderate to good yields with a wide functional group tolerance under simple and metal-free conditions. This transformation provided convenient practical route important functionalized thiobenzamides.

Language: Английский

Citations

4
BX3-mediated borylation for the synthesis of organoboron compounds DOI
Chunhua Yang

Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(23), P. 6010 - 6020

Published: Jan. 1, 2023

This review summarizes the recent progress in borylation driven by BX 3 fields of organic synthesis and drug synthesis.

Language: Английский

Citations

10
Strategic 1,n-migration of boronate complexes: a novel platform for remote C–C bond construction DOI
Yiming Chen, Xue Li, Zhigang Xu

et al.

Molecular Diversity, Journal Year: 2025, Volume and Issue: unknown

Published: April 2, 2025

Language: Английский

Citations

0
BBr3-Mediated ortho C–H Borylation of Benzamides DOI
Yixuan Liang,

Chengyu Du,

C. Dong

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

We have developed a BBr3-mediated, metal-free ortho C-H borylation of benzamides, enabling the synthesis wide range ortho-borylated benzamides in moderate to good yields. This transformation offers convenient strategy for accessing functionalized which are valuable intermediates pharmaceuticals, agrochemicals, and fine chemical synthesis.

Language: Английский

Citations

0
Photocatalyst‐ and Transition Metal‐Free Light‐Induced Borylation Reactions DOI
Rosalin Bhanja, Shyamal Kanti Bera, Prasenjit Mal

et al.

Chemistry - An Asian Journal, Journal Year: 2023, Volume and Issue: 18(21)

Published: Sept. 25, 2023

The increasing global warming concerns have propelled a surge in the demand for sustainable energy sources within domain of synthetic organic chemistry. A particularly prominent area research has been development mild strategies generating heterocyclic compounds. Heterocyclic compounds containing boron notably risen to prominence as pivotal reagents myriad transformations, showcasing their wide-ranging applicability. This comprehensive review is aimed at collecting literature pertaining borylation reactions induced by light, specifically focusing on photocatalyst-free and transition metal-free methodologies. central emphasis delving into selective mechanistic investigations. amalgamation analysis these insights elucidate substantial potential inherent eco-friendly approaches synthesizing compounds, thus propelling landscape

Language: Английский

Citations

9
Selective Synthesis of Boron-Functionalized Indenes and Benzofulvenes by BCl3-Promoted Cyclizations of ortho-Alkynylstyrenes DOI Creative Commons

Marcos Humanes,

Ester Sans-Panadés,

Cintia Virumbrales

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(31), P. 6568 - 6573

Published: July 29, 2024

A selective, metal-free synthesis of boron-functionalized indenes and benzofulvenes via BCl

Language: Английский

Citations

2
Unsaturated (C(sp2/sp)–B) Boronic Acid Derivatives DOI

Olivia M. Schneider,

Dawson J. Konowalchuk, Dennis G. Hall

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

1
Carbonyl group directed synthesis of 3-boryl-3-substituted alkenyl oxindoles and tetrasubstituted β-borylenones DOI

Debraj Ghorai,

Kanak Kanti Das, Santanu Panda

et al.

Chemical Communications, Journal Year: 2023, Volume and Issue: 59(97), P. 14447 - 14450

Published: Jan. 1, 2023

Transition metal-free carbonyl directed boron-Wittig reaction of α-bis(boryl)carbanions with the corresponding isatins or α-keto esters/amides was achieved to access alkenyl oxindoles in good yield and high stereoselectivity.

Language: Английский

Citations

2
Light-assisted functionalization of aryl radicals towards metal-free cross-coupling DOI
Huaibo Zhao,

Valentina Dafnae Cuomo,

Wei Tian

et al.

Nature Reviews Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

Language: Английский

Citations

0
B(C6F5)3‐Catalyzed [2+3]‐Cyclative o,m‐diC‐H Functionalization of Phenols DOI

Jingyan Luo,

Zhou Luo,

Biqi Zhang

et al.

Chemistry - A European Journal, Journal Year: 2023, Volume and Issue: 29(71)

Published: Sept. 28, 2023

Metal-free catalytic C-H functionalization is highly desired for the construction of C-C bonds. We herein report a chemoselective consecutive [2+3]-cyclative simultaneous formation two bonds with polycyclic phenols catalyzed by commercially available and low-cost B(C6 F5 )3 . This system tolerates wide range substrate scope, providing series 2,6,7,8-tetrahydroacenaphthylen-3-ol-type compounds efficiently. Several derivatizations products have also been conducted to show potential application this method in synthesis compounds.

Language: Английский

Citations

0