Nitrogenation of Alkynes with Nitrones to Prepare Functionalized [1,4]Oxazinones through Csp–Csp2 Bond Cleavage DOI
Yu Zhao, L. Yan,

Lin-Fen Liao

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(44), P. 9541 - 9546

Published: Oct. 25, 2024

Herein, we report a novel strategy of hypervalent iodine(III) compound-mediated selective Csp–Csp2 bond cleavage alkynes and C═N/N–O nitrones recombination C–C/C–O/C–N multiple bonds to access various functionalized [1,4]oxazinones bearing vicinal carbon stereocenter in good yields high diastereoselectivity. Mechanistic studies revealed that the reaction undergoes domino [4 + 3] cycloaddition, 1,3-rearrangement N–O bond, intramolecular cyclization, dearomatization, rearomatization over four steps single flask. The present method features functional group tolerance, broad substrate scope, C–C/C═N/N–O recombination.

Language: Английский

Design, synthesis, and iodine adsorption performances of indole-derived porous organic polymers DOI
Yuqun Zhuo,

Luna Song,

Min Yang

et al.

Polymer, Journal Year: 2025, Volume and Issue: unknown, P. 128106 - 128106

Published: Jan. 1, 2025

Language: Английский

Citations

2
Metal- and oxidant-free skeletal reorganizing of oxazolidines to access N-Vinylpyrroles DOI

Ruidan Shi,

Xianjun Xu,

Ling Zhong

et al.

Sustainable Chemistry and Pharmacy, Journal Year: 2024, Volume and Issue: 42, P. 101768 - 101768

Published: Sept. 17, 2024

Language: Английский

Citations

3
Access to Spiro-Quinazolines via an Acid-Catalyzed Ring-Opening of Isatins with N-Alkylureas DOI

Yuchen Rong,

Jian‐Quan Liu, Xiang‐Shan Wang

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 25, 2025

Herein, we report novel p-TSA·H2O-catalyzed ring-opening reactions of isatins with N-alkylureas, allowing access to spiro-quinazolines excellent substrate scope and good yields. Introducing N,N-dialkylureas, 2,4-thiazolidinedione, or rhodamine into the leads a distinct set three-component reactions, yielding innovative incorporating sulfur atoms. Notably, protocol achieves superior level atomic economy, water as sole byproduct.

Language: Английский

Citations

0
Recent advances in the application of contiguously functionalized aziridines for the synthesis of pharmaceutical precursors via regioselective ring-opening reactions DOI
Huimyoung Byeon, Hyun‐Joon Ha, Jung Woon Yang

et al.

Molecular Catalysis, Journal Year: 2025, Volume and Issue: 576, P. 114943 - 114943

Published: Feb. 26, 2025

Language: Английский

Citations

0
Synthesis of indolizines via Pd-catalyzed selective ring recasting of oxazolidines with deesterification of methyl acrylates DOI

Ya Pan,

Xianjun Xu,

Junwei Li

et al.

Sustainable Chemistry and Pharmacy, Journal Year: 2025, Volume and Issue: 46, P. 102059 - 102059

Published: June 5, 2025

Language: Английский

Citations

0
Nitrogenation of Alkynes with Nitrones to Prepare Functionalized [1,4]Oxazinones through Csp–Csp2 Bond Cleavage DOI
Yu Zhao, L. Yan,

Lin-Fen Liao

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(44), P. 9541 - 9546

Published: Oct. 25, 2024

Herein, we report a novel strategy of hypervalent iodine(III) compound-mediated selective Csp–Csp2 bond cleavage alkynes and C═N/N–O nitrones recombination C–C/C–O/C–N multiple bonds to access various functionalized [1,4]oxazinones bearing vicinal carbon stereocenter in good yields high diastereoselectivity. Mechanistic studies revealed that the reaction undergoes domino [4 + 3] cycloaddition, 1,3-rearrangement N–O bond, intramolecular cyclization, dearomatization, rearomatization over four steps single flask. The present method features functional group tolerance, broad substrate scope, C–C/C═N/N–O recombination.

Language: Английский

Citations

0