Expert Review of Molecular Diagnostics, Journal Year: 2024, Volume and Issue: 24(6), P. 497 - 508
Published: June 2, 2024
Inflammatory bowel disease (IBD), encompassing Crohn's (CD) and Ulcerative Colitis (UC), is a relapsing remitting condition. Noninvasive biomarkers have an increasingly important role in the diagnosis of IBD prediction future course individuals with IBD. Strategies for management rely upon close monitoring gastrointestinal inflammation.
Language: Английский
Nutrients, Journal Year: 2024, Volume and Issue: 16(14), P. 2302 - 2302
Published: July 17, 2024
Inflammatory bowel disease (IBD), a complex chronic inflammatory disorder that includes Crohn’s (CD) and Ulcerative Colitis (UC), has become globally increasing health concern. Nutrition, as an important factor influencing the occurrence development of IBD, attracted more attention. As most nutrient, protein can not only provide energy nutrition required by patients, but also help repair damaged intestinal tissue, enhance immunity, thus alleviate inflammation. Numerous studies have shown nutritional support plays significant role in treatment remission IBD. This article presents comprehensive review pathogenesis IBD analyzes summarizes potential mechanisms Additionally, it provides overview clinical effects its impact on complications. Research findings reveal demonstrates benefits improving symptoms, reducing risk complications, quality life patients. Therefore, is expected to new approach for
Language: Английский
Citations
4
Clinical Rheumatology, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 12, 2025
Osteoarthritis knee poses a substantial and pervasive global health challenge. The data was extracted from the Global Burden of Disease 2021 Study database. First, numbers age-standardized rates (ASRs) incidence, prevalence, disability-adjusted life years (DALYs) osteoarthritis were assessed globally by sub-types in 2021. Subsequently, we employed linear regression model to analyze temporal trends 1990 To predict future burden, utilized age-period-cohort Bayesian model. Furthermore, conducted sensitivity analysis using Autoregressive Integrated Moving Average Exponential Smoothing In 2021, accounted for 30.85 million incidence cases, 374.74 prevalence 12.02 DALYs cases globally, with ASRs 353.67, 4294.27, 137.59, respectively. Females individuals over 50 old identified as high-risk populations, while higher socio-demographic index regions emerged areas. From rose 14.13 million, 159.80 5.15 accompanied increases their respective ASRs. Projections APC continued increase both genders until 2046. Specifically, male are projected 18.45 female 25.60 million. Similarly, rise 235.41 365.97 Male expected 7.52 11.55 BAPC models also indicate an upward trend number cases. conclusion, represents formidable threat public health, necessitating development proactive tailored strategic interventions that account global-specific contexts. Key Points • populations. Higher disease burden attributable increased 2019. deaths would still next 25 years.
Language: Английский
Citations
0
Journal Of Advanced Zoology, Journal Year: 2024, Volume and Issue: 45(1), P. 778 - 784
Published: Jan. 24, 2024
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn’s (CD), represents a persistent gastrointestinal inflammatory condition. Initially labeled as "Western disease," IBD was predominantly associated with Western lifestyles, but shift in dietary lifestyle patterns has led to noticeable rise Asian populations. The global prevalence of reached 6.8 million cases 2017, subsequent decrease 4.9 2019, showcasing dynamic occurrence. multifactorial pathogenesis involves genetic susceptibility, environmental factors, an aberrant immune response the gut microbiota. is classified into CD, affecting any part tract, UC, limited colon rectum. A third category, IBD-unspecified (IBD-U), utilized when inflammation's origin unclear. Complications, including strictures, fistulas, colorectal cancer, emphasize disease's severity. Treatment options range from aminosalicylates biologics, emerging therapies focus on mucosal antibacterial barrier offering potential advancements. Global healthcare organizations, recognizing ailment, aim summarize epidemiological guide interventions. In study burden 40 were reported, more than 1 percent total incidence been seen worldwide, 41.00 thousand deaths, 1622.50 DALYs globally 2019. While advancements have made, further research crucial improve prevention treatment strategies. pathogenic towards barriers presents avenue for future developments, hope enhanced outcomes improved quality life individuals affected by
Language: Английский
Citations
0
Expert Review of Molecular Diagnostics, Journal Year: 2024, Volume and Issue: 24(6), P. 497 - 508
Published: June 2, 2024
Inflammatory bowel disease (IBD), encompassing Crohn's (CD) and Ulcerative Colitis (UC), is a relapsing remitting condition. Noninvasive biomarkers have an increasingly important role in the diagnosis of IBD prediction future course individuals with IBD. Strategies for management rely upon close monitoring gastrointestinal inflammation.
Language: Английский
Citations
0