Preparation, Modification, Food Application, and Health Effects of Protein and Peptide from Hemp (Cannabis sativa L.) Seed: A Review of the Recent Literature DOI Creative Commons
Xiaoqin Zhang, Wei Zhou, Xiaoli Qin

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(7), P. 1149 - 1149

Published: March 26, 2025

Hemp is a multiuse crop used for fiber, food, and medicinal purposes. The seed of hemp has attracted great attention as good plant protein resource with remarkable nutritional biological properties. However, the application (HSP) limited due to its unsatisfactory functional Physical, chemical, technologies have been explored modify structure HSP improve functionality. investigation activity derived peptide deal intestinal, metabolic, muscle concerns broadened utilization in healthy products. Therefore, current review performed summarize recent research progress on novel extraction modification HSP, well purification identification active peptide. multi-functional multi-bioactive properties adverse effects are also depicted facilitate their potential applications food industry.

Language: Английский

The Application and Mechanism Analysis of Enteral Nutrition in Clinical Management of Chronic Diseases DOI Open Access
Qingye Li, Jing Wang

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 450 - 450

Published: Jan. 26, 2025

Chronic diseases have emerged as a significant challenge in global public health due to their complex etiologies, prolonged disease courses, and high treatment costs. With the aging population changes lifestyle, number of patients with chronic has increased dramatically, which brought heavy burden families society. are often accompanied by digestive absorptive disorders well metabolic disorders, resulting insufficient nutrient intake, further worsening condition weakening physique. Therefore, importance nutritional intervention management become increasingly prominent. As an important means intervention, enteral nutrition plays key role improving status patients, promoting rehabilitation, shortening hospital stay so on, thereby providing new solution for management. This article reviews current application status, mechanism action comprehensive benefit clinical diseases. Through systematic review analysis existing research findings, specific effects mechanisms clarified. aims promote popularization nutrition, order effectively improve patients’ outcomes quality life, provide scientific evidence optimization strategies diseases, offer theoretical support development products, drive continuous improvement

Language: Английский

Citations

0
In Vitro Inhibition of Endoplasmic Reticulum Stress: A Promising Therapeutic Strategy for Patients with Crohn’s Disease DOI Creative Commons
Bruno Lima Rodrigues, Lívia Bitencourt Pascoal, Lívia Moreira Genaro

et al.

Cells, Journal Year: 2025, Volume and Issue: 14(4), P. 270 - 270

Published: Feb. 13, 2025

Crohn's disease (CD) is an inflammatory bowel marked by abnormal immune response and excessive pro-inflammatory cytokines, leading to impaired protein processing endoplasmic reticulum (ER) stress. This stress, caused the accumulation of misfolded proteins, triggers unfolded (UPR) through IRE1/Xbp-1, PERK/eIF2α, ATF6 pathways, which are linked intestinal inflammation. study aimed investigate ER stress in CD patients' mucosa evaluate phenylbutyrate (PBA) as inhibitor. Colon biopsies from patients controls were cultured under five conditions, including 4-PBA treatments. Real-time PCR, cytokine level, immunohistochemistry performed. Immunohistochemistry revealed that was activated epithelial cells lamina propria cells. but not IRE1/Xbp-1 or ATF6, upregulated compared controls. UPR-related genes (STC2, CALR, HSPA5, HSP90B1) also elevated patients. PBA treatment significantly reduced UPR markers while decreasing apoptotic like DDIT3. Pro-inflammatory such IL-1β, IL-6, IL-17, TNF- α, sCD40L, after treatment. pathways colonic mucosa, reduces these markers, suggesting potential therapeutic benefits for CD-related

Language: Английский

Citations

0
Sodium butyrate alleviates DSS-induced inflammatory bowel disease by inhibiting ferroptosis and modulating ERK/STAT3 signaling and intestinal flora DOI Creative Commons

Yingyin Liu,

Nan Chen, Han He

et al.

Annals of Medicine, Journal Year: 2025, Volume and Issue: 57(1)

Published: March 3, 2025

Background Inflammatory bowel disease (IBD), encompassing Crohn's (CD) and ulcerative colitis (UC), can seriously impact patients' quality of life. Sodium butyrate (NaB), a product dietary fiber fermentation, has been shown to alleviate IBD symptoms. Some studies have that it is related ferroptosis. However, the precise mechanism linking NaB, IBD, ferroptosis not clear.

Language: Английский

Citations

0
Preparation, Modification, Food Application, and Health Effects of Protein and Peptide from Hemp (Cannabis sativa L.) Seed: A Review of the Recent Literature DOI Creative Commons
Xiaoqin Zhang, Wei Zhou, Xiaoli Qin

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(7), P. 1149 - 1149

Published: March 26, 2025

Hemp is a multiuse crop used for fiber, food, and medicinal purposes. The seed of hemp has attracted great attention as good plant protein resource with remarkable nutritional biological properties. However, the application (HSP) limited due to its unsatisfactory functional Physical, chemical, technologies have been explored modify structure HSP improve functionality. investigation activity derived peptide deal intestinal, metabolic, muscle concerns broadened utilization in healthy products. Therefore, current review performed summarize recent research progress on novel extraction modification HSP, well purification identification active peptide. multi-functional multi-bioactive properties adverse effects are also depicted facilitate their potential applications food industry.

Language: Английский

Citations

0