Advances in orthopedic implants: the role of nanotechnology in enhancing performance and longevity

Regenerative medicine reports ., Journal Year: 2025, Volume and Issue: 2(1), P. 15 - 21

Published: Feb. 6, 2025

Traditional orthopedic implants, despite being broadly accepted, come with numerous limitations such as low osseointegration, mechanical wear, and vulnerability to infection, thus causing complications consequent revision surgeries. Nanotechnology provides an innovative approach materials at the nanoscale, enhancing efficacy of implants used. This necessitates development that respond human movement, demonstrate greater durability, can be used for extended periods. Nanostructured surfaces coatings mimic conditions natural bone, promoting superior cell adhesion, proliferation, differentiation, which are essential both successful osseointegration bone regeneration. Moreover, use nanocoatings exhibit outstanding antibacterial properties, thereby reducing risk postoperative infections. Each component in a nanocomposite, ceramics, polymers, metals, contributes excellent performance stability effectively addressing issues related implant wearing failure. In addition, nanotechnology also facilitates incorportion drug delivery systems within allowing localized controlled release antibiotics or growth factors. targeted enhances healing minimizes side effects other parts body. Despite its capability transformation, challenges scalability manufacturing, potential toxicity, immunogenic responses, regulatory approval processes remain. review focuses on applications highlighting how these have impacted efficacy, strength, delivery. offers promising improving patient care better, complications, transforming future orthopedics. To fully realize potential, it is investigate current explore new areas research.

Language: Английский

---

Polyetheretherketone biomaterials and their current progress, modification-based biomedical applications and future challenges

Materials & Design, Journal Year: 2025, Volume and Issue: unknown, P. 113716 - 113716

Published: Feb. 1, 2025

Language: Английский

---

Hüftchirurgie: 3-D-gedruckte Implantate in der Revisionsendoprothetik

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 10, 2025

The adoption of 3D printing technology in hip surgery marks a substantial leap forward orthopedic surgery. This innovative approach allows for the creation patient-specific implants that significantly enhance fit and functionality. In our study, we demonstrate different uses 3D-printing techniques their preoperative, intraoperative, postoperative use treatment complex acetabular defects. Moreover, clinical outcomes 3D-printed have been discussed. By overcoming many limitations traditional manufacturing methods, facilitates production geometries highly porous structures improve implant fixation promote better bone ingrowth. We believe upcoming years, with help new technical improvements, will increase.

Language: Английский

---

4D Bioprinting for Personalized Medicine, Innovations in Implant Fabrication and Regenerative Therapies

Polymer-Plastics Technology and Materials, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 26

Published: March 30, 2025

Language: Английский

---

Biomechanics and Mechanobiology of Additively Manufactured Porous Load‐Bearing Bone Implants

Small, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Abstract Given that they can replicate both the biomechanical and mechanobiological functions of natural bone, metal additively manufactured porous load‐bearing bone implants present a significant advancement in orthopedic applications. Additive manufacturing (AM) metals enables precise control over pore geometry, resulting provide effective mechanical support minimize stress shielding. In addition to its benefits, architecture facilitates essential processes, including transmission signals regulate cellular processes such as adhesion, proliferation, differentiation. Before clinical use, should first be engineered achieve comparable elastic modulus native mitigating implant‐induced resorption while promoting tissue regeneration. It is also noteworthy microstructural features these angiogenesis‐a critical process for oxygen nutrient delivery during healing. Despite their potential challenges remain balancing stability applications with biofunctionality integration controlled degradation. This review comprehensively discusses factors influencing design performance implants, highlighting enhance outcomes repair

Language: Английский

---

Advanced Materials in Orthopedics

Published: Jan. 1, 2025

Language: Английский

---

Energy Input Effects on the Microstructure and Mechanical Behavior of Ti–Nb Alloy Additively Manufactured by Electron Beam Melting

Materials Science and Engineering A, Journal Year: 2025, Volume and Issue: unknown, P. 148480 - 148480

Published: May 1, 2025

Language: Английский

---

A comprehensive review of additively manufactured biomedical titanium-based alloys for bone tissue engineering: Biocorrosion, biomechanical, and biological properties

Journal of Materials Research and Technology, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Language: Английский

---

Advancements in 3D printing of functional materials for biomedical applications: challenges, opportunities, and case studies: a critical review

Progress in Additive Manufacturing, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 19, 2024

Language: Английский

---

Micro- and Nanostructured Biomaterials for Biomedical Applications and Regenerative Medicine

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(22), P. 1845 - 1845

Published: Nov. 18, 2024

Over the past two decades, research on innovative micro- and nano-biomaterials has seen a significant surge in bioengineering, biomedicine, regenerative medicine fields [...].

Language: Английский

---