IntechOpen eBooks,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 13, 2024
Quercetin,
a
naturally
occurring
flavonoid,
has
gained
significant
attention
in
recent
years
due
to
its
potential
health
benefits
and
versatile
applications.
This
book
chapter
explores
the
chemistry
of
quercetin,
shedding
light
on
molecular
structure,
biosynthesis,
extraction
methods.
The
delves
into
extensive
research
effects
highlighting
antioxidant,
anti-inflammatory,
anticancer,
neuroprotective,
cardioprotective
properties.
Moreover,
risks
toxicity
associated
with
quercetin
consumption
are
thoroughly
examined,
emphasizing
importance
proper
dosage
drug
interactions.
concludes
by
providing
an
overview
advances
development,
including
nanoformulations,
targeted
delivery
systems,
combination
therapies,
that
hold
promise
for
enhancing
therapeutic
efficacy
bioavailability.
comprehensive
exploration
aims
provide
researchers,
scientists,
healthcare
professionals
valuable
insights
multifaceted
nature
applications
human
health.
International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 9659 - 9688
Published: Sept. 1, 2024
Reactive
oxygen
species
(ROS)
encompass
a
diverse
group
of
chemically
reactive
molecules
or
ions
distinguished
by
their
substantial
oxidative
potential.
Empirical
studies
have
shown
that
the
targeted
administration
high
toxic
concentrations
ROS
can
effectively
induce
tumor
cell
death
in
various
types.
Numerous
bioactive
ingredients
derived
from
traditional
Chinese
medicine
(TCM),
recognized
for
ROS-inducing
properties,
demonstrated
significant
anti-tumor
activity.
Nonetheless,
clinical
application
has
been
hindered
challenges
such
as
low
solubility,
limited
bioavailability,
and
poor
selectivity.
Multifunctional
nanoformulations
possess
potential
to
overcome
these
enhance
anticancer
efficacy
active
compounds.
Through
extensive
searches
academic
databases
thorough
review
screening
relevant
literature,
this
study
aims
systematically
summarize
generalize
multiple
TCM
generation,
along
with
multifunctional
nanoformulations,
perspectives.
The
objective
is
provide
new
insights
references
fundamental
cancer
research
treatments.
Furthermore,
we
acknowledge
although
numerous
potentials,
potentially
offering
novel
strategies
therapy,
underlying
mechanisms
require
further
comprehensive
investigation.
IntechOpen eBooks,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 13, 2024
Quercetin,
a
naturally
occurring
flavonoid,
has
gained
significant
attention
in
recent
years
due
to
its
potential
health
benefits
and
versatile
applications.
This
book
chapter
explores
the
chemistry
of
quercetin,
shedding
light
on
molecular
structure,
biosynthesis,
extraction
methods.
The
delves
into
extensive
research
effects
highlighting
antioxidant,
anti-inflammatory,
anticancer,
neuroprotective,
cardioprotective
properties.
Moreover,
risks
toxicity
associated
with
quercetin
consumption
are
thoroughly
examined,
emphasizing
importance
proper
dosage
drug
interactions.
concludes
by
providing
an
overview
advances
development,
including
nanoformulations,
targeted
delivery
systems,
combination
therapies,
that
hold
promise
for
enhancing
therapeutic
efficacy
bioavailability.
comprehensive
exploration
aims
provide
researchers,
scientists,
healthcare
professionals
valuable
insights
multifaceted
nature
applications
human
health.
