A Review of the Role of Micronutrients and Bioactive Compounds on Immune System Supporting to Fight against the COVID-19 Disease DOI Creative Commons
Montaña Cámara, María de Cortes Sánchez‐Mata, Virginia Fernández-Ruíz

et al.

Foods, Journal Year: 2021, Volume and Issue: 10(5), P. 1088 - 1088

Published: May 14, 2021

Micronutrients are critical for an adequate function of the immune system and play a vital role in promoting health nutritional well-being. The present work is aimed at reviewing (1) micronutrients helping to fight against COVID-19 disease through diet with food or supplements (2) potential use claims regarding according European Food Safety Authority (EFSA) requirements. Till date, there some authorized by Commission that refer certain essential nutrients (vitamins B

Language: Английский

Gastrointestinal Manifestations of SARS-CoV-2: Transmission, Pathogenesis, Immunomodulation, Microflora Dysbiosis, and Clinical Implications DOI Creative Commons
Siva Sundara Kumar Durairajan, Abhay Singh, Udhaya Bharathy Saravanan

et al.

Viruses, Journal Year: 2023, Volume and Issue: 15(6), P. 1231 - 1231

Published: May 24, 2023

The clinical manifestation of COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in system humans is widely recognized. There increasing evidence suggesting that SARS-CoV-2 possesses capability to invade gastrointestinal (GI) system, leading symptoms such as vomiting, diarrhea, abdominal pain, and GI lesions. These subsequently contribute development gastroenteritis inflammatory bowel disease (IBD). Nevertheless, pathophysiological mechanisms linking these infection remain unelucidated. During infection, binds angiotensin-converting enzyme other host proteases tract during possibly causing damaging intestinal barrier stimulating factor production, respectively. COVID-19-induced IBD include inflammation, mucosal hyperpermeability, bacterial overgrowth, dysbiosis, changes blood fecal metabolomics. Deciphering pathogenesis COVID-19 understanding its exacerbation may provide insights into prognosis pave way for discovery potential novel targets prevention or treatment. Besides usual transmission routes, can also be transmitted via feces an infected person. Hence, it crucial implement preventive control measures order mitigate fecal-to-oral SARS-CoV-2. Within this context, identification diagnosis infections assume significance they facilitate early detection targeted therapeutics. present review discusses receptors, pathogenesis, SARS-CoV-2, with a particular focus on induction gut immune responses, influence microbes, therapeutic against IBD.

Language: Английский

Citations

24

<i>Clostridioides difficile</i> infection in coronavirus disease 2019: an underestimated problem? DOI Open Access
Konrad Lewandowski, Mariusz Rosołowski, Magdalena Kaniewska

et al.

Polskie Archiwum Medycyny Wewnętrznej, Journal Year: 2020, Volume and Issue: unknown

Published: Dec. 14, 2020

ARTICLE Clostridioides difficile infection in COVID -19 121 transcription-polymerase chain reaction test.The treatment of is mainly symptomatic and based on international research guidelines. 7,8Recommended drugs include chloroquine, hydroxychloroquine, azithromycin, lopinavir / ritonavir. 9The use tocilizumab remdesivir can be considered severely ill patients. 10,11As the rates bacterial coinfections are high, empiric antibiotic therapy often necessary. 7It has been estimated that over INTROduCTION On March 11, 2020, World Health Organization announced a pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS -CoV -2). 1-3The most common symptoms disease 2019 (COVID -19) SARS -2 fever (83%-99%), cough (59%-82%), fatigue (44%-70%), diarrhea (2%-50%). 2,4-6The diagnosis established detecting RNA reverse

Language: Английский

Citations

56

COVID-19: An overview and a clinical update DOI Open Access
Arunkumar Krishnan, James P. Hamilton, Saleh A. Alqahtani

et al.

World Journal of Clinical Cases, Journal Year: 2020, Volume and Issue: 9(1), P. 8 - 23

Published: Dec. 29, 2020

The outbreak of coronavirus disease-2019 (COVID-19, previously known as 2019 nCoV) caused by severe acute respiratory syndrome 2 (SARS-CoV-2) infection in Wuhan City, China, has spread rapidly around the world. Most patients from first cluster had an epidemiological connection to Wuhan's Huanan Seafood Wholesale Market. Available evidence shown that SARS-CoV-2 can be easily transmitted person through close contact and droplets, posing a substantial challenge public health. At present, research on is still primary stages. However, dexa-methasone remdesivir are appeared promising medical therapies. Still, there no definite specific treatment, mainstay treatment focused supportive Currently, over 150 vaccines under investigation. It necessary understand nature virus its clinical characteristics order find effectively manage disease. knowledge about this evolving, clinicians must update themselves regularly. present review comprehensively summarizes epidemiology, pathogenesis, characteristics, management COVID-19 based current evidence.

Language: Английский

Citations

53

Antibacterial, Antiviral, Antioxidant, and Anticancer Activities of Postbiotics: A review of Mechanisms and Therapeutic Perspectives DOI Open Access
Leili Aghebati‐Maleki, Paniz Hasannezhad, Amin Abbasi

et al.

Biointerface Research in Applied Chemistry, Journal Year: 2021, Volume and Issue: 12(2), P. 2629 - 2645

Published: June 24, 2021

Several scientific evidence has shown the advantageous effects of probiotic-derived metabolites on human health. Postbiotics are a wide range bioactive compounds derived from probiotics through fermentation process and/or produced in pure forms laboratory scales. These have native biological activities that been extensively studied recent years. Immunomodulation, antimicrobial, anti-cancer, antioxidant, anti-diabetic, and reduction food allergies compose most important roles postbiotics. In terms safety, it confirmed postbiotics, as potential substitute elements, might be superior to their parent live cells. Also, due appropriate economic, technological, clinical features, they could employed favorable apparatuses drug industry improve health benefits. This review comprehensively discusses concept postbiotics characteristics, emphasizing antibacterial, antiviral, anticancer activities.

Language: Английский

Citations

51

A Review of the Role of Micronutrients and Bioactive Compounds on Immune System Supporting to Fight against the COVID-19 Disease DOI Creative Commons
Montaña Cámara, María de Cortes Sánchez‐Mata, Virginia Fernández-Ruíz

et al.

Foods, Journal Year: 2021, Volume and Issue: 10(5), P. 1088 - 1088

Published: May 14, 2021

Micronutrients are critical for an adequate function of the immune system and play a vital role in promoting health nutritional well-being. The present work is aimed at reviewing (1) micronutrients helping to fight against COVID-19 disease through diet with food or supplements (2) potential use claims regarding according European Food Safety Authority (EFSA) requirements. Till date, there some authorized by Commission that refer certain essential nutrients (vitamins B

Language: Английский

Citations

47