International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(17), P. 9605 - 9605
Published: Sept. 4, 2024
The
petal
blight
disease
of
alpine
Rhododendron
severely
impacts
the
ornamental
and
economic
values
Rhododendron.
Plant
secondary
metabolites
play
a
crucial
role
in
resisting
pathogenic
fungi,
yet
research
on
petals
that
confer
resistance
to
fungi
is
limited.
In
present
study,
delavayi,
R.
agastum,
irroratum
with
anti-pathogenic
activity
were
screened
through
index
analysis,
metabolomic
detection,
mycelial
growth
rate,
metabolite
spraying
experiments.
Disease
analysis
revealed
delavayi
exhibited
strongest
resistance,
while
agastum
showed
weakest,
both
under
natural
experimental
conditions.
UHPLC-QTOF-MS/MS
identified
355
274
putative
positive
negative
ion
modes,
respectively.
further
antifungal
differentially
accumulated
baicalein,
diosmetin,
naringenin
their
half-inhibitory
concentrations
(IC50)
against
Neopestalotiopsis
clavispora
be
5000
mg/L,
1000
Spraying
exogenous
significantly
alleviated
caused
by
N.
infection
petals,
inhibition
rates
exceeding
64%.
This
study
suggests
naringenin,
particularly
can
recommended
as
inhibitory
agents
for
preventing
controlling
Borneo Journal of Pharmacy,
Journal Year:
2024,
Volume and Issue:
7(1), P. 1 - 13
Published: Feb. 29, 2024
Candida
albicans
can
cause
two
infections
in
humans:
superficial
and
systemic.
The
ability
of
C.
to
infect
the
host
is
influenced
by
virulence
factors
character
changes
so
that
it
fool
immune
system.
From
change
factor,
form
a
biofilm.
This
study
aims
determine
good
concentration
inhibiting
antifungal
antibiofilm
activity
nanoemulsion
mouthwash
formulation
bajakah
tampala
(Spatholobus
littoralis
Hassk)
skin
extract
against
albicans.
research
was
conducted
with
an
experimental
method.
used
spontaneous
magnetic
stirrer
technique
make
preparations.
Antifungal
tests
were
carried
out
dilution
method
using
96-well
plate
microplate
reader
wavelength
620
nm
percentage
inhibition
MIC50
MBIC50.
results
showed
S.
inhibited
planktonic
biofilm
1%
expressed
as
Therefore,
could
inhibit
growth
oral
cavity.
The
pharmacopoeia
of
the
Democratic
Republic
Congo
(DRC)
contains
monographs
on
various
medicinal
plants
with
pharmacological
properties,
whose
knowledge
and
use
is
rapidly
eroding.To
document
remaining
knowledge,
we
conducted
an
ethnobotanical
survey
in
territories
Kisantu
Mbanza-Ngungu
Kongo-Central
