Study on Fabrication and Properties of Polyvinyl Alcohol/Chitosan Nanofibers Created from Aqueous Solution with Acetic Acid and Ethanol by the Electrospinning Method DOI Open Access
Thi Hong Nhung Vu, С. Н. Морозкина, Roman O. Olekhnovich

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(23), P. 3393 - 3393

Published: Nov. 30, 2024

The development of nanofibers with incorporated biologically active molecules a targeted mode action is current research trend. Potential materials for the such systems include poly(vinyl alcohol) (PVA) and chitosan (CS) nanofibers, which are traditionally fabricated by electrospinning aqueous solutions these polymers acetic acid. To improve drug integration, ethanol was added to binary-solvent system. This results in several important data: noticeable shifts solvent system’s solubility parameter, interaction various component forces, optical rheological properties PVA-CS solution. use electrospun solution also contributes adjusting parameters Teas graph, maintaining “fh − fd” optimal region fabrication nanofibers. Increasing efficiency nanofiber quite difficult due requirements parameters, technological environmental parameters; however, this increased work 2 3 times more morphology. These demonstrate that containing 4% PVA, 3% CS, 15% ethanol, 45% acid increasing productivity, improving morphology diameter without changing chemical bonds. XRD spectrum revealed alterations crystal lattice led variation their thermal tensile properties.

Language: Английский

A systematic investigation of solution and technological parameters for the fabrication and characterization of poly (vinyl alcohol–chitosan electrospun nanofibers DOI
Thi Hong Nhung Vu, С. Н. Морозкина, Vera E. Sitnikova

et al.

Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(5)

Published: May 1, 2024

Abstract Nanomaterials, particularly nanofibers are demonstrating exceptional potential for medical applications considered as promising systems the integration of drug molecules, providing an enhancement effectiveness and safety, while reducing side effects. Nanofibers based on two polymeric matrices poly(vinyl alcohol) (PVA) chitosan (CS) have been demonstrated to be safe materials targeted delivery. This article studied factors influencing fabrication properties PVA–CS nanofibers, including impact solution components structure, rheological properties, electrospinning technology parameters, well structure thermomechanical obtained investigated in details. The increasing acetic acid concentration has effect pH lowering electrical conductivity heightening its viscosity. pH, conductivity, viscosity values rises CS increases. Based Hildebrand‐Scatchard solubility theory, calculated Teas diagrams that account intermolecular interactions allow predict low‐defect binary solvent with a greater hydrogen bonds. optimal content parameters were determined. Infrared spectroscopy confirmed polymer good interaction was completely separated from nanofibers. XRD spectrum reveals crystal lattice change according ratio. polymers ratio also influence thermal tensile properties. Such biosafe may delivery mode action.

Language: Английский

Citations

1
Acceleration of chondrogenic differentiation utilizing Biphasic Core-Shell Alginate Sulfate Electrospun Nanofibrous Scaffold DOI

Elmira Omrani,

Mohammad Amin Haramshahi,

Najmeh Najmoddin

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 242, P. 114080 - 114080

Published: July 9, 2024

Language: Английский

Citations

1
Electrospinning of Biocompatible Nanofibres for Medical Coatings: Techniques and Applications DOI
Bancha Yingngam,

Kamonrat Suksumrit,

N. Proykratok

et al.

Royal Society of Chemistry eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 214 - 250

Published: Nov. 15, 2024

The development of biocompatible nanofibres through electrospinning is a promising method for engineers in the biomedical field. existing coating technologies medical field have various limitations, and more investigations are needed to improve their biocompatibility, controlled release properties, mechanical strength. Designing new materials that can interact efficiently with biological systems offer numerous functional advantages major challenge device manufacturing tissue engineering. This chapter reviews approaches used create nanofibres, including design, fabrication functionalization. applications these coatings also reviewed. Furthermore, we discuss methods, used, key parameters impact fibre morphology physiochemical properties. Moreover, incorporation bioactive elements drugs into therapeutic explored. biologically friendly be an effective approach improving coatings. Such enhance properties such as drug delivery, regeneration, implant integration, offering enormous potential patient welfare. Future research areas include investigating use advanced procedures enhanced control over nanofibre composition design fabrication.

Language: Английский

Citations

1
Study on Fabrication and Properties of Polyvinyl Alcohol/Chitosan Nanofibers Created from Aqueous Solution with Acetic Acid and Ethanol by the Electrospinning Method DOI Open Access
Thi Hong Nhung Vu, С. Н. Морозкина, Roman O. Olekhnovich

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(23), P. 3393 - 3393

Published: Nov. 30, 2024

The development of nanofibers with incorporated biologically active molecules a targeted mode action is current research trend. Potential materials for the such systems include poly(vinyl alcohol) (PVA) and chitosan (CS) nanofibers, which are traditionally fabricated by electrospinning aqueous solutions these polymers acetic acid. To improve drug integration, ethanol was added to binary-solvent system. This results in several important data: noticeable shifts solvent system’s solubility parameter, interaction various component forces, optical rheological properties PVA-CS solution. use electrospun solution also contributes adjusting parameters Teas graph, maintaining “fh − fd” optimal region fabrication nanofibers. Increasing efficiency nanofiber quite difficult due requirements parameters, technological environmental parameters; however, this increased work 2 3 times more morphology. These demonstrate that containing 4% PVA, 3% CS, 15% ethanol, 45% acid increasing productivity, improving morphology diameter without changing chemical bonds. XRD spectrum revealed alterations crystal lattice led variation their thermal tensile properties.

Language: Английский

Citations

1