Molecules,
Journal Year:
2025,
Volume and Issue:
30(6), P. 1370 - 1370
Published: March 19, 2025
The
propolis
produced
by
stingless
bees
is
a
complex
mixture
of
natural
sticky
components
mixed
with
soil
or
clay.
Global
research
on
has
focused
studying
the
biological
and
pharmacological
properties
chemical
composition
bee
from
Brazil,
Indonesia,
other
regions.
However,
studies
in
Mexico
are
scarce.
This
study
aimed
to
determine
geopropolis
Scaptotrigona
mexicana
collected
Totonacapan
region
evaluate
its
antioxidant
antibacterial
activities.
phenolic
contents
ethanolic
extract
ranged
2.45
±
0.03
mg
GAE/g
3.48
0.56
dry
extract.
total
flavonoid
content
0.69
QE/g
0.84
0.009
activity
extracts
was
assessed
via
DPPH,
ABTS,
FRAP
assays.
minimum
inhibitory
concentration
values
exhibited
(>512
g/mL)
for
Gram-negative
bacteria
(Pseudomonas
aerugunosa
Phorphyromonas
gingivalis)
were
higher
than
those
Gram-positive
bacteria.
showed
highest
against
Streptococcus
mutans
(256
g/mL).
Five
known
compounds,
taraxeryl
acetate
(1),
lupeol
(3),
cicloart-23-en-3β,25-diol
(5),
mangiferoic
acid
(6),
5-(11’Z-heptadecenyl)-resorcinol
(7),
two
irresoluble
mixtures
3-O-acetyl-α-(2a)
3-O-acetyl-β-amyrins
(2b),
α-
(4a)
-amyrins
(4b),
identified
nuclear
magnetic
resonance
spectroscopy
mass
spectrometry.
Additionally,
39
volatile
compounds
headspace-solid
phase
microextraction
using
hyphenated
gas
chromatography
coupled
spectrometry
time-of-flight.
main
detected
include
trans-α-bergamotene
(8.15%),
hexanal
(7.17%),
2-heptanone
(7.60%),
α-copaene
(7.09%).
Oxford University Press eBooks,
Journal Year:
2019,
Volume and Issue:
unknown
Published: June 27, 2019
Abstract
Tropical
East
Asia
is
home
to
over
1
billion
people
and
faces
massive
human
impacts
from
its
rising
population
rapid
economic
growth.
It
has
already
lost
more
than
half
of
forest
cover
the
highest
rates
deforestation
logging
in
tropics.
Hunting
trade
wildlife
products
threaten
all
large
many
smaller
vertebrates.
Despite
these
problems,
region
still
supports
an
estimated
15–25
per
cent
global
terrestrial
biodiversity
thus
a
key
focus
for
conservation.
This
book
therefore
deals
with
plants,
animals,
ecosystems
they
inhabit,
as
well
diverse
threats
their
survival
options
provides
background
knowledge
region’s
ecology
needed
by
both
specialists
non-specialists
put
own
work
into
broader
context.
The
first
edition
was
describe
entire
Asian
tropics
subtropics,
southern
China
western
Indonesia,
second
extended
coverage
include
very
similar
Northeast
India,
Bangladesh,
Bhutan.
third
updates
contents
gives
prominence
Anthropocene
possible
conservation
responses.
accessible
style,
comprehensive
coverage,
engaging
illustrations
make
this
advanced
textbook
essential
read
senior
undergraduate
graduate-level
students
studying
tropics,
authoritative
reference
professional
ecologists,
conservationists,
interested
amateurs
worldwide.
Revista Brasileira de Farmacognosia,
Journal Year:
2018,
Volume and Issue:
29(3), P. 389 - 399
Published: Dec. 19, 2018
Stingless
bee
products
such
as
honey,
pollen,
propolis,
and
geopropolis
have
been
used
for
centuries
in
traditional
medicine
the
treatment
of
several
illnesses.
Investigation
biological
activity
stingless
products,
especially
propolis
geopropolis,
has
revealed
promising
therapeutic
properties.
About
20%
total
Neotropical
bees
can
be
found
Brazil.
Despite
species
diversity,
studies
on
their
are
scarce.
The
present
review
focuses
antioxidant
antimicrobial
activities
from
Brazilian
bees.
In
addition,
toxicity
these
natural
was
addressed.
order
to
provide
new
evidences
toxic
potential
components,
an
silico
analysis
performed
using
ADMET
PredictorTM
software.
We
observed
that
most
evaluated
only
crude
ethanol
extracts
a
limited
number
species.
Propolis
displayed
capacity
activity.
Concerning
potential,
were
considered
safe.
Nonetheless,
vitro
vivo
toxicological
still
necessary.
Foods,
Journal Year:
2021,
Volume and Issue:
10(5), P. 997 - 997
Published: May 2, 2021
Recently,
the
honey
and
propolis
of
stingless
bees
have
been
attracting
growing
attention
because
their
health-promoting
properties.
However,
studies
on
these
products
African
Meliponini
are
still
very
scarce.
In
this
preliminary
study,
we
analyzed
chemical
composition
honey,
two
cerumen,
resin
deposits
(propolis)
samples
Meliponula
ferruginea
from
Tanzania.
The
M.
was
profiled
by
NMR
indicated
different
long-term
stability
Apis
mellifera
European
(Bulgarian)
honey.
It
differed
significantly
in
sugar
organic
acids
content
had
a
high
amount
disaccharide
trehalulose,
known
for
its
bioactivities.
We
suggested
trehalulose
to
be
potential
marker
bee
analogously
recent
proposal
Asia,
South
America,
Australia
demonstrated
easy
discrimination
13C
NMR.
Propolis
cerumen
were
studied
GC-MS
(gas
chromatography-mass
spectometry).
contained
mainly
terpenoids
(di-and
triterpenes)
but
qualitative
quantitative
differences.
This
fact
an
indication
that
possibly
has
no
strict
preferences
resins
used
construct
protect
nests.
antimicrobial
anti-quorum
sensing
properties
materials
also
tested.
These
first
results
rich
biologically
active
substances
deserved
further
research.
International Journal of Molecular Sciences,
Journal Year:
2020,
Volume and Issue:
21(14), P. 4988 - 4988
Published: July 15, 2020
Propolis
is
a
natural
resinous
material
produced
by
bees
and
has
been
used
in
folk
medicines
since
ancient
times.
Due
to
it
possessing
broad
spectrum
of
biological
activities,
gained
significant
scientific
commercial
interest
over
the
last
two
decades.
As
result
searching
122
publications
reported
up
end
2019,
we
assembled
unique
compound
database
consisting
578
components
isolated
from
both
honey
bee
propolis
stingless
propolis,
analyzed
chemical
space
diversity
these
compounds.
The
results
demonstrated
that
are
valuable
sources
for
pharmaceutical
nutraceutical
development.
Saudi Journal of Biological Sciences,
Journal Year:
2021,
Volume and Issue:
28(12), P. 7182 - 7189
Published: Aug. 10, 2021
Our
effort
to
find
new
material
for
anti
cancer
from
natural
resources
leads
us
focus
on
stingless
bee
products
such
as
honey,
pollen,
and
propolis.
The
were
seven
bees
named
Homotrigona
fimbriata,
Heterotrigona
itama,
bakeri,
Tetragonula
sarawakensis,
testaceitarsis,
fuscobalteata,
laeviceps.
evaluated
their
cytotoxicity
effect
MCF-7,
HeLa
Caco-2
cell
lines.
This
is
the
first
time
be
reported
that
ethanol
extracts
of
pollen
propolis
H.
fimbriata
displayed
more
potent
than
other
products.
By
chromatography
biological
activity-guided
fractionation,
extract
was
fractionated
isolated
its
active
compound
mangiferonic
acid.
Mangiferonic
acid
showed
a
with
IC50
values
96.76
µM
in
>110.04
HeLa,
>
110.04
Caco-2,
respectively.
These
results
exhibited
potential
further
developed
drug
experiments
verify
function
are
essential.
Food Production Processing and Nutrition,
Journal Year:
2023,
Volume and Issue:
5(1)
Published: May 4, 2023
Abstract
The
breeding
of
stingless
bees,
known
as
meliponiculture,
can
be
found
throughout
the
world,
and
is
closely
linked
to
history
first
human
communities
in
Americas.
This
activity
provides
products
industrial
interest
(food,
cosmetics,
pharmaceuticals),
among
them
propolis
stands
out.
matrix
a
resinous
material
but
being
difficult
classify
conceptualize
due
its
variability
according
environment
producing
species.
produced
by
these
bees
source
compounds
with
nutritional
functional
potential,
main
focused
on
phenolic
compounds.
potential
makes
product
that
used
prospection
new
molecules
antimicrobial
antioxidant
activity.
Thus,
scientific
literature
describes
(generally
extracts)
against
bacteria
fungi,
higher
microbicidal
gram-positive
bacteria.
high
this
bee
consequence
presence
several
use
from
SBP
(Stingless
propolis)
still
quite
limited,
generally
restricted
studies
application
other
sectors
benefit
productive
sector,
Apis
mellifera
.
work
presents
discusses
composition
consequent
biological
activities,
well
applications
food
industry.
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