Antimicrobial activity of flavonoids glycosides and pyrrolizidine alkaloids from propolis of Scaptotrigona aff. postica DOI

T. M. Cantero,

Pedro Ismael da Silva, Giuseppina Negri

et al.

Toxin Reviews, Journal Year: 2022, Volume and Issue: 42(1), P. 300 - 315

Published: Dec. 16, 2022

Language: Английский

Production of chitosan-based biodegradable active films using bio-waste enriched with polyphenol propolis extract envisaging food packaging applications DOI Creative Commons

Cristiane De Carli,

Volkan Aylanç,

Kheira M. Mouffok

et al.

International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 213, P. 486 - 497

Published: May 29, 2022

Developing biodegradable active films has been a promising green approach to overcoming global concerns over the environmental pollution and human health caused by plastic utilization. This study aimed develop based on chitosan (CS), produced from waste crayfish (Procambarus clarkii) shells enriched with bioactive extract (5-20%) of propolis (PS) characterize its properties, envisaging food packaging applications. The chromatographic profile PS confirmed richness, 41 phenolic compounds. With increasing addition chitosan, thickness increased 61.7 71.7 μm, causing reduction in light transmission rate, along greenish colour shift. interactions between CS was infrared spectroscopy, at same time that microstructural integrity checked scanning electron microscopy micrographs. findings also showed enhanced thermal stability mechanical properties e.g., tensile modulus, yield strength, stress break. Besides, it improved antioxidant antimicrobial activities. Overall, CS-based composite seem alternative petroleum-based synthetic plastics allowing extend shelf life products due their eco-friendly nature.

Language: Английский

Citations

74

Stingless Bee (Apidae: Apinae: Meliponini) Ecology DOI Creative Commons
David W. Roubik

Annual Review of Entomology, Journal Year: 2022, Volume and Issue: 68(1), P. 231 - 256

Published: Oct. 6, 2022

Stingless bees form perennial colonies of honey-making insects. The >600 species stingless bees, mainly Neotropical, live throughout tropical latitudes. Foragers influence floral biology, plant reproduction, microbe dispersal, and diverse ecosystem functions. As forest residents since the upper Cretaceous, they have had a long evolutionary history without competition from honey bees. Most are smaller than any Apis recruit nest mates to resources, while their defense strategies exclude stinging behavior but incorporate biting. diversified ecologically; excel in nesting site selection mutualisms with plants, arthropods, microbes; display opportunism, including co-opting defenses. biology becomes better known, applications human endeavors imposing selective pressures exploitation approaches conservation that entail colony extraction wildlands. Although some meliponines can adjust new conditions, populations shall require diversity for survival reproduction.

Language: Английский

Citations

72

Experimental Evidence for Therapeutic Potentials of Propolis DOI Open Access
Priyanshu Bhargava, Debajit Mahanta,

A. Kaul

et al.

Nutrients, Journal Year: 2021, Volume and Issue: 13(8), P. 2528 - 2528

Published: July 24, 2021

Propolis is produced by honeybees from materials collected plants they visit. It a resinous material having mixtures of wax and bee enzymes. also known as glue used bees building in their hives, for blocking holes cracks, repairing the combs strengthening thin borders. has been extensively since ancient times different purposes traditional human healthcare practices. The quality composition propolis depend on its geographic location, climatic zone local flora. New Zealand Brazilian green are two main kinds that have studied recent years. Their bioactive components found to possess variety therapeutic potentials. was improves cognitive functions mild impairments patients living at high altitude protects them neurodegenerative damage through antioxidant properties. possesses artepillin C (ARC) key component, anticancer potential. contains caffeic acid phenethyl ester (CAPE) with multiple Our lab performed vitro vivo assays extracts prepared active ingredients. We provided experimental evidence these anticancer, antistress hypoxia-modulating activities. Furthermore, conjugation γCD proved be more effective. In present review, we portray showing potential candidate drug ailments improve life.

Language: Английский

Citations

66

Facile fabrication and characterization of high-performance Borax-PVA hydrogel DOI
Chen Wang,

Zhifeng Shen,

Pengfei Hu

et al.

Journal of Sol-Gel Science and Technology, Journal Year: 2021, Volume and Issue: 101(1), P. 103 - 113

Published: July 16, 2021

Language: Английский

Citations

62

Freshwater fungal biology DOI Creative Commons
Mark S. Calabon,

KD Hyde,

Ebg Jones

et al.

Mycosphere, Journal Year: 2023, Volume and Issue: 14(1), P. 195 - 413

Published: Jan. 1, 2023

Research into freshwater fungi has generated a wealth of information over the past decades with various published articles, i.e., reviews, books, and monographs.With advancement methodologies used in fungal research, numerous mycologists working on this ecological group, our knowledge progress understanding fungi, including novel discoveries new insights ecology advanced.With enormous progress, it is timely that an updated account be compiled one volume.Thus, to give comprehensive overview different facets biology.It includes classification scheme based latest taxonomic phylogenetic analysis taxa, their evolutionary history.The biology, diversity, geographical distribution higher basal are also discussed entries.A section dispersal adaptation filamentous included present work.The importance role breakdown wood habitats, physiology, detail.The biotechnological potential as producers bioactive metabolites reviewed, antimicrobial drug discovery.The volume provides high throughput sequencing (HTS) platforms for research highlighting advantages challenges, recent studies HTS identification quantification communities habitats.The identifies gaps direction future fungi.

Language: Английский

Citations

31

Bioactive Polyphenolic Compounds from Propolis of Tetragonula carbonaria in the Gibberagee Region, New South Wales, Australia DOI Creative Commons

Dylan W. Ebner,

D. L. Woods,

Trong D. Tran

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(6), P. 965 - 965

Published: March 12, 2025

Stingless bee propolis has emerged globally as a new source of bioactive molecules that can advance human health. However, limited research been conducted on Australian stingless propolis. This study investigated the chemical composition and biological activity produced by bees Tetragonula carbonaria from Gibberagee, distinct region New South Wales state in Australia. Using bioassay-guided fractionation, twelve compounds were isolated, including six A-ring methylated flavonoids. Nine these demonstrated strong scavenging against 2,2-diphenyl-1-picrylhydrazyl radicals, with five exhibiting greater potency than vitamin C. Chemical structures seven additional minor flavonoids determined through an intensive MS/MS data analysis. In silico screening 19 revealed all, except for gallic acid, displayed higher binding affinity to α-glucosidase antidiabetic drug, voglibose. showed Gibberagee is promising nutraceutical cosmeceutical applications owing its antioxidant properties. The unique profile C-methylated potentially provides valuable insights into botanical origin.

Language: Английский

Citations

2

Cheminformatics to Characterize Pharmacologically Active Natural Products DOI Creative Commons
José L. Medina‐Franco, Fernanda I. Saldívar‐González

Biomolecules, Journal Year: 2020, Volume and Issue: 10(11), P. 1566 - 1566

Published: Nov. 17, 2020

Natural products have a significant role in drug discovery. distinctive chemical structures that contributed to identifying and developing drugs for different therapeutic areas. Moreover, natural are sources of inspiration or starting points develop new agents. such as peptides macrocycles, other compounds with unique features represent attractive address complex diseases. Computational approaches use chemoinformatics molecular modeling methods contribute speed up product-based Several research groups recently used computational methodologies organize data, interpret results, generate test hypotheses, filter large databases before the experimental screening, design experiments. This review discusses broad range applications support We emphasize profiling product data sets terms diversity; complexity; acid/base; absorption, distribution, metabolism, excretion, toxicity (ADME/Tox) properties; fragment analysis. Novel techniques visual representation space also discussed.

Language: Английский

Citations

64

Antifungal Properties of Chemically Defined Propolis from Various Geographical Regions DOI Creative Commons
Marcin Ożarowski, Tomasz M. Karpiński, Rahat Alam

et al.

Microorganisms, Journal Year: 2022, Volume and Issue: 10(2), P. 364 - 364

Published: Feb. 4, 2022

Long-term fungal infections that are difficult to treat require new substances for their prevention, treatment, or as adjuvants during antibiotic therapy. Propolis is a very promising source of natural show wide range pharmacological properties, including antifungal activity against various strains. The purpose the literature review was summarize recent studies (PubMed, Scopus) on progress in evaluating chemically defined propolis extracts. During selection studies, only those with results expressed minimal inhibitory concentration (MIC) and/or fungicidal (MFC) were analyzed. Moreover, plant, animal and environmental factors influencing chemical composition discussed. Mechanisms extracts research trends aspect developing therapies assessment drug interactions indicated. shows there great definition After comparing MIC/MFC values, it assessed offer not pathogenic Candida strains but also risky molds; however, strength this varied.

Language: Английский

Citations

33

Novel self-healing and recyclable fire-retardant polyvinyl alcohol/borax hydrogel coatings for the fire safety of rigid polyurethane foam DOI
Xiaodong Qian,

Nire Mu,

Xiaojiong Zhao

et al.

Soft Matter, Journal Year: 2023, Volume and Issue: 19(32), P. 6097 - 6107

Published: Jan. 1, 2023

Rigid polyurethane foam (RPUF) has attracted great attention as an insulation material, but its inherent flammability restricts practical application.

Language: Английский

Citations

18

Geographic Area of Collection Determines the Chemical Composition and Antimicrobial Potential of Three Extracts of Chilean Propolis DOI Creative Commons
Marysol Alvear, Estela Santos, Felipe Cabezas

et al.

Plants, Journal Year: 2021, Volume and Issue: 10(8), P. 1543 - 1543

Published: July 28, 2021

The biological properties of chilean propolis have been described and include antibacterial, antifungal antibiofilm activities. Propolis has a strong antimicrobial potential. Clinical experiences with synthetic antibiotics indicated the need to discover new sources bioactive compounds associated ethnopharmacological knowledge or natural such as propolis. microscopic analysis pollen grains from plants allows us determine botanical origin samples. In Angol, sample were obtained fodder (Sorghum bicolor; Lotus sp.) trees, Acacia sp., Pinus radiata, Eucalyptus sp. Salix babylonica. Maule region contains endemic Quillaja saponaria. Finally, Melipilla presented wider variety extracted vegetable species.Colorimetric assays performed quantify total polyphenols present in Chilean samples established that PCP2 (Angol sample) showed high amounts phenolics compounds, significant statistical differences comparison other main identified pinocembrin, quercetin caffeic acid phenethyl ester (CAPE). Angol content polyphenols.Studies influence geographical floral variables on chemical composition are valuable source information for study its properties.

Language: Английский

Citations

40