bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Nov. 2, 2023
Abstract
Rhythmicity
is
a
cornerstone
of
behavioral
and
biological
processes,
especially
metabolism,
yet
the
mechanisms
behind
metabolite
cycling
remain
elusive.
This
study
uncovers
robust
oscillation
in
key
pathways
downstream
glucose
humans.
A
purpose-built
13
C
6
-glucose
isotope
tracing
platform
was
used
to
sample
Drosophila
every
4h
probe
these
pathways,
revealing
striking
peak
biosynthesis
shortly
after
lights-on
wild-type
flies.
hyperactive
mutant
(
fumin
)
demonstrates
increased
Krebs
cycle
labelling
dawn-specific
glycolysis
labelling.
Surprisingly,
neither
underlying
feeding
rhythms
nor
presence
food
availability
explain
rhythmicity
processing
across
genotypes,
suggesting
internal
mechanism
for
metabolic
control
processing.
These
results
align
with
clinical
data
highlighting
detrimental
effects
mistimed
energy
intake.
Our
approach
offers
unique
insight
into
dynamic
range
daily
provides
mechanistic
foundation
exploring
circadian
homeostasis
disease
contexts.
Estudios y Perspectivas Revista Científica y Académica,
Journal Year:
2025,
Volume and Issue:
4(4), P. 2336 - 2349
Published: Jan. 16, 2025
La
salud
es
una
parte
esencial
del
ser
humano
y
se
define
como
el
completo
bienestar
bio-psico
social
humano.
En
profesores
universitarios
ha
reportado
que
entre
40%
80%
de
ellos,
encuentran
con
alteraciones
la
salud,
tales
enfermedades
cardiometabólicas,
posturales,
trastornos
neurológicos
sensoriales,
defectos
en
alimentación,
malos
hábitos
sueño,
estrés
bajo
nivel
aptitud
física.
Esto
afecta
su
desempeño
docentes.
Se
documenta
por
sus
inadecuados
vida.
Participaron
voluntariamente
248
516
(99
mujeres
149
hombres)
quienes
respondieron
a
invitación
hizo
Coordinación
Recursos
Humanos
Universidad.
encontraron
prevalencias
elevadas
riesgo
cardiometabólico
población
estudiada;
asociadas
patologías
obesidad,
hipertensión
arterial,
alimentación
un
capacidad
física,
lo
disminuye
años
vida
productiva,
Nueve
cada
diez
participantes
estudio
manifestaron
deseo
participar
manera
continua
permanente
programas
para
adopción
estilos
saludables.
Estudios
complementarios
son
necesarios
intervención
prevención
estados
ulteriores
daño
salud.
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(3), P. 781 - 781
Published: Jan. 25, 2025
(1)
Background/Objectives:
Cardiovascular
diseases
(CVD)
are
the
leading
cause
of
morbidity
and
mortality
globally,
necessitating
effective
risk
prediction
strategies.
This
study
was
aimed
at
developing
validating
a
multivariate
predictive
model
integrating
body
composition
lipid
profile
to
assess
cardiovascular
in
an
adult
population.
(2)
Methods:
A
cross-sectional
analysis
90
participants
from
general
Spanish
population
conducted.
Participants
were
classified
into
groups
(low,
medium,
high)
based
on
systolic
blood
pressure.
(3)
Results:
Descriptive
multinomial
logistic
regression
analyses
revealed
significant
associations
between
specific
parameters,
such
as
visceral
fat,
glucose
levels,
waist-to-hip
ratio.
Visceral
adiposity
emerged
strong
predictor
high
risk,
highlighting
its
critical
role
health.
Glucose
levels
also
significantly
associated
with
increased
underscoring
importance
metabolic
health
outcomes.
Contrary
expectations,
markers
like
cholesterol
triglycerides
did
not
show
variations
across
categories,
suggesting
that
traditional
profiles
may
fully
capture
group.
Waist-to-hip
ratio
showed
transitions,
particularly
low
medium
emphasizing
fat
distribution
patterns.
(4)
Conclusions:
These
findings
suggest
composition,
is
crucial
determinant
more
personalized
assessment
approaches
move
beyond
markers.
Nutrition Journal,
Journal Year:
2025,
Volume and Issue:
24(1)
Published: April 28, 2025
Inconsistent
epidemiologic
findings
on
the
associations
of
chrononutrition
behaviors
with
diet
quality
and
adiposity
measures
may
be
due
to
use
different
dietary
assessment
methodologies
a
lack
consideration
misreporting.
We
aimed
investigate
by
using
questionnaires
diaries,
adjustment
for
energy
intake
(EI)
This
cross-sectional
study
included
1047
Japanese
adults
aged
20-69
years.
used
Chrono-Nutrition
Behavior
Questionnaire
(CNBQ)
or
11-day
diaries
assess
(meal
frequency,
snack
total
eating
timing
first
occasion,
last
duration
window,
midpoint)
workdays
non-workdays
separately.
Eating
jetlag
was
defined
as
midpoint
difference
between
non-workdays.
Diet
assessed
Healthy
Index-2020,
based
Meal-based
History
(MDHQ)
4-day
weighed
food
diaries.
EI
misreporting
evaluated
Goldberg
cut-off
principle.
Using
questionnaire
data
(CNBQ
MDHQ),
we
found
inverse
frequencies,
midpoint,
(P
<
0.05),
irrespective
Also,
positive
meal,
snack,
frequencies
window
prevalence
general
obesity
(body
mass
index
≥
25
kg/m2),
abdominal
(waist
circumference
90
cm
males;
80
females),
both;
many
these
were
only
evident
0.05)
after
In
contrast,
diary
data,
no
quality,
obesity,
regardless
(except
timings
occasions
quality).
The
dependent
methodology
behaviors.
Adjustment
radically
changed
in
questionnaire-based
analysis.
These
suggest
importance
careful
method
selection
research.
Journal of Hypertension,
Journal Year:
2024,
Volume and Issue:
42(6), P. 951 - 960
Published: April 2, 2024
The
purpose
of
this
review
is
to
synthesize
results
from
studies
examining
the
association
between
time-of-day
for
eating,
exercise,
and
sleep
with
blood
pressure
(BP)
in
adults
elevated
BP
or
hypertension.
Six
databases
were
searched
relevant
publications
which
789
identified.
Ten
met
inclusion
criteria.
Four
examined
five
one
their
associations
BP.
Results
suggested
that
later
eating
(
n
=
2/4)
mid-point
1/1)
significantly
related
higher
multivariable
models,
whereas
morning
3/5)
evening
4/5)
exercise
associated
lower
Although
small
body
work
limited
by
a
lack
prospective,
randomized
controlled
study
designs
underutilization
24
h
ambulatory
assessment,
these
provide
preliminary,
hypothesis-generating
support
independent
role
npj Metabolic Health and Disease,
Journal Year:
2024,
Volume and Issue:
2(1)
Published: Dec. 30, 2024
Intermittent
fasting
focuses
on
the
timing
of
eating
rather
than
diet
quality
or
energy
intake,
with
evidence
supporting
its
effects
weight
loss
and
improvements
in
cardiometabolic
outcomes
adults
obesity.
However,
there
is
limited
for
feasibility
efficacy
young
people.
To
address
this,
a
scoping
review
was
conducted
to
examine
intermittent
regimens
individuals
aged
10
25
treatment
obesity
focusing
methodology,
intervention
parameters,
outcomes,
adherence,
feasibility,
efficacy.
Due
paucity
this
age
group,
adequately
assess
all
published
studies
category,
regardless
status
intention,
were
included
review.
The
34
(28
interventional
6
observational
studies)
893
participants
12
25.
Interventions
varied
9
cohorts
utilizing
as
an
treatment.
Thirteen
utilized
8-h
time-restricted
eating.
Primary
risk
factors
(7/28),
anthropometric
measurements
body
composition
(5/28),
muscular
performance
(4/28),
(1/28),
others
(4/28).
All
people
reported
some
degree
loss,
although
comparator
groups
significantly.
This
underscores
various
utilizations
group
highlights
potential
treating
findings
emphasize
need
rigorous
standardized
frameworks
ensure
comparability
determine
fasting's
practicality
depending
outcome
interest.
Research Society and Development,
Journal Year:
2024,
Volume and Issue:
13(5), P. e9513545799 - e9513545799
Published: May 22, 2024
O
ciclo
circadiano
é
o
mecanismo
de
adequação
do
organismo
à
duração
dia
e
da
noite.
Através
dos
relógios
biológicos,
corpo
humano
consegue
adequar
os
processos
fisiológicos
aos
acontecimentos
cíclicos
diários.
desbalanceamento
desses
pode
impactar
negativamente
no
organismo,
resultando
em
desordens
metabólicas.
desenvolvimento
sintomas
oriundos
síndrome
pré-menstrual
depende,
dentre
outros
fatores,
relação
com
padrão
ingestão
alimentar,
que
agravar
ou
amenizar
esses
sintomas.
A
aplicação
crononutrição
como
intervenção
terapêutica
restabelecimento
homeostase
abrandamento
período
menstrual
tem-se
mostrado
promissora.
Dessa
maneira,
objetivo
desta
pesquisa
a
análise
impactos
alimentar
nas
fases
menstrual,
além
investigação
sobre
potencial
nesse
ciclo.
As
bases
dados
utilizadas
para
consulta
foram
SCIELO,
EBSCO,
CAPES,
PUBMED.
Verifica-se
as
pesquisas,
geral,
indicam
influência
direta
biológicos
funções
metabólicas,
salientar
dietético
uma
das
funcionamento
metabolismo
hormonal,
demonstrando
eficácia
possibilidade
Ainda
assim,
percebe-se
escassez
estudos
acerca
assunto,
dificulta
estabelecimento
estratégia
nutricional
mais
assertiva.
Verificou-se,
portanto,
pesquisas
geral
demandam
maior
investimento
tema
seja
fato
estabelecida
tratamento
ocasionados
menstrual.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 1, 2024
Intermittent
fasting
(IF)
focuses
on
the
timing
of
eating
rather
than
diet
quality
or
energy
intake,
with
evidence
supporting
its
effects
weight
loss
and
cardiometabolic
outcomes
in
adults.
However,
there
is
limited
for
efficacy
adolescents
emerging
To
address
this,
a
scoping
review
examined
IF
regimens
individuals
aged
10
to
25,
focusing
methodology,
intervention
parameters,
outcomes,
adherence,
feasibility,
efficacy.
The
included
39
studies
731
participants
15
25.
Methodologies
varied,
18
time-restricted
others
requiring
caloric
restriction.
Primary
risk
factors
(11/29),
body
composition
(9/29),
anthropometric
measurements
(8/29),
feasibility
(2/29).
Most
reported
significant
loss.
This
underscores
IF's
potential
treating
obesity
this
age
group
but
highlights
need
rigorous
standardized
frameworks
ensure
comparability
determine
practicality
group.