Evaluation of ChatGPT’s Potential in Tailoring Gynecological Cancer Therapies DOI Open Access
Annika Krückel,

Lena Brückner,

Iason Psilopatis

et al.

In Vivo, Journal Year: 2024, Volume and Issue: 38(4), P. 1649 - 1659

Published: Jan. 1, 2024

Background/Aim: Demographic change and increasing complexity of therapy decisions lead to a growing burden on the healthcare system, necessitating efforts simplify enhance efficiency patient care. The present study evaluates ChatGPT's ability provide recommendations for gynecological malignancies that are both in line with local guidelines individually tailored patient. Patients Methods: Sixteen patients endometrial, cervical, ovarian cancer who were treated clinic University Hospital Erlangen from January 2022 August 2023 included analysis. Data collected within clinical routine care communicated chat-based AI model ChatGPT (version 3.5). performance generating treatment plans evaluated using an answer scoring system descriptive Results: According [range: −1 point (minimum) 2 points (maximum)], demonstrated good potential average score 0.75 cancer, 0.7 cervical 1.5 endometrial patients. most common deductions about incomplete recommendations, whereas contraindicated modalities rarely suggested. Individual characteristics regularly considered by ChatGPT. reliably indicated aftercare provided detailed information preventive measures as well supportive treatment. Conclusion: is promising tool generation suggestions carcinomas high flexibility response individual differences. At current state, however, not suitable replacing expert panels.

Language: Английский

Utilizing large language models in breast cancer management: systematic review DOI Creative Commons
Vera Sorin, Benjamin S. Glicksberg, Yaara Artsi

et al.

Journal of Cancer Research and Clinical Oncology, Journal Year: 2024, Volume and Issue: 150(3)

Published: March 19, 2024

Despite advanced technologies in breast cancer management, challenges remain efficiently interpreting vast clinical data for patient-specific insights. We reviewed the literature on how large language models (LLMs) such as ChatGPT might offer solutions this field.

Language: Английский

Citations

14

Toward Clinical Generative AI: Conceptual Framework DOI Creative Commons
Nicola Luigi Bragazzi, Sergio Garbarino

JMIR AI, Journal Year: 2024, Volume and Issue: 3, P. e55957 - e55957

Published: May 6, 2024

Clinical decision-making is a crucial aspect of health care, involving the balanced integration scientific evidence, clinical judgment, ethical considerations, and patient involvement. This process dynamic multifaceted, relying on clinicians’ knowledge, experience, intuitive understanding to achieve optimal outcomes through informed, evidence-based choices. The advent generative artificial intelligence (AI) presents revolutionary opportunity in decision-making. AI’s advanced data analysis pattern recognition capabilities can significantly enhance diagnosis treatment diseases, processing vast medical identify patterns, tailor treatments, predict disease progression, aid proactive management. However, incorporation AI into raises concerns regarding reliability accuracy AI-generated insights. To address these concerns, 11 “verification paradigms” are proposed this paper, with each paradigm being unique method verify nature paper also frames concept “clinically explainable, fair, responsible, clinician-, expert-, patient-in-the-loop AI.” model focuses ensuring comprehensibility, collaborative nature, grounding, advocating for serve as an augmentative tool, its processes transparent understandable clinicians patients. should enhance, not replace, clinician’s judgment involve continuous learning adaptation based real-world legal compliance. In conclusion, while holds immense promise enhancing decision-making, it essential ensure that produces evidence-based, reliable, impactful knowledge. Using outlined paradigms approaches help communities harness potential maintaining high care standards.

Language: Английский

Citations

12

Assessing the role of advanced artificial intelligence as a tool in multidisciplinary tumor board decision-making for primary head and neck cancer cases DOI Creative Commons
Benedikt Schmidl,

Tobias Hütten,

Steffi Pigorsch

et al.

Frontiers in Oncology, Journal Year: 2024, Volume and Issue: 14

Published: May 24, 2024

Background Head and neck squamous cell carcinoma (HNSCC) is a complex malignancy that requires multidisciplinary approach in clinical practice, especially tumor board discussions. In recent years, artificial intelligence has emerged as tool to assist healthcare professionals making informed decisions. This study investigates the application of ChatGPT 3.5 4.0, natural language processing models, decision-making. Methods We conducted pilot October 2023 on 20 consecutive head cancer patients discussed our (MDT). Patients with primary diagnosis were included. The MDT 4.0 recommendations for each patient compared by two independent reviewers number therapy options, recommendation, explanation summarization graded. Results this study, provided mostly general answers surgery, chemotherapy, radiation therapy. For scored well, but demonstrated be an assisting tool, suggesting significantly more options than MDT, while some recommended treatment modalities like immunotherapy are not part current guidelines. Conclusions research demonstrates advanced AI models at moment can merely setting, since versions list common sometimes recommend incorrect case lack information source material.

Language: Английский

Citations

12

ChatGPT Generated Training Plans for Runners are not Rated Optimal by Coaching Experts, but Increase in Quality with Additional Input Information DOI Creative Commons
Peter Düking, Billy Sperlich, Laura Voigt

et al.

Journal of Sports Science and Medicine, Journal Year: 2024, Volume and Issue: unknown, P. 56 - 72

Published: Jan. 12, 2024

ChatGPT may be used by runners to generate training plans enhance performance or health aspects. However, the quality of generated based on different input information is unknown. The objective study was evaluate ChatGPT-generated six-week for granularity. Three were using 22 criteria drawn from literature and coaching experts a 1-5 Likert Scale. A Friedmann test assessed significant differences in between plans. For 1, 2 3, median rating <3 given 19, 11, 1 times, 3 5, 8 times >3 0, 6, 13 respectively. Training plan received significantly lower ratings compared criteria, 15 (p < 0.05). 0.05) 9 criteria. are ranked sub-optimally experts, although increases when more provided. An understanding aspects relevant programming distance running important, we advise avoiding use without an expert coach's feedback.

Language: Английский

Citations

10

Evolution of publicly available large language models for complex decision-making in breast cancer care DOI Creative Commons
Sebastian Griewing, Johannes Knitza,

Jelena Boekhoff

et al.

Archives of Gynecology and Obstetrics, Journal Year: 2024, Volume and Issue: 310(1), P. 537 - 550

Published: May 29, 2024

Abstract Purpose This study investigated the concordance of five different publicly available Large Language Models (LLM) with recommendations a multidisciplinary tumor board regarding treatment for complex breast cancer patient profiles. Methods Five LLM, including three versions ChatGPT (version 4 and 3.5, data access until September 3021 January 2022), Llama2, Bard were prompted to produce 20 LLM compared (gold standard), surgical, endocrine systemic treatment, radiotherapy, genetic testing therapy options. Results GPT4 demonstrated highest (70.6%) invasive profiles, followed by GPT3.5 2021 (58.8%), 2022 (41.2%), Llama2 (35.3%) (23.5%). Including precancerous lesions ductal carcinoma in situ, identical ranking was reached lower overall each (GPT4 60.0%, 50.0%, 35.0%, 30.0%, 20.0%). achieved full (100%) radiotherapy. Lowest alignment recommending testing, demonstrating varying (55.0% 2022, up 85.0% GPT4). Conclusion early feasibility is first compare care regard changes accuracy over time, i.e., more or through technological upgrades. Methodological advancement, optimization prompting techniques, development, enabling input control secure processing, are necessary preparation large-scale multicenter studies provide evidence on their safe reliable clinical application. At present, evidenced use not yet feasible.

Language: Английский

Citations

9

Reliability of artificial intelligence chatbot responses to frequently asked questions in breast surgical oncology DOI
Estefania Roldan‐Vasquez,

Samir Mitri,

Shreya Bhasin

et al.

Journal of Surgical Oncology, Journal Year: 2024, Volume and Issue: 130(2), P. 188 - 203

Published: June 4, 2024

Artificial intelligence (AI)-driven chatbots, capable of simulating human-like conversations, are becoming more prevalent in healthcare. While this technology offers potential benefits patient engagement and information accessibility, it raises concerns about misuse, misinformation, inaccuracies, ethical challenges.

Language: Английский

Citations

9

The Role of Artificial Intelligence on Tumor Boards: Perspectives from Surgeons, Medical Oncologists and Radiation Oncologists DOI Creative Commons
Valerio Nardone, Federica Marmorino, Marco Maria Germani

et al.

Current Oncology, Journal Year: 2024, Volume and Issue: 31(9), P. 4984 - 5007

Published: Aug. 27, 2024

The integration of multidisciplinary tumor boards (MTBs) is fundamental in delivering state-of-the-art cancer treatment, facilitating collaborative diagnosis and management by a diverse team specialists. Despite the clear benefits personalized patient care improved outcomes, increasing burden on MTBs due to rising incidence financial constraints necessitates innovative solutions. advent artificial intelligence (AI) medical field offers promising avenue support clinical decision-making. This review explores perspectives clinicians dedicated patients-surgeons, oncologists, radiation oncologists-on application AI within MTBs. Additionally, it examines role across various specialties involved treatment. By analyzing both potential challenges, this study underscores how can enhance discussions optimize treatment plans. findings highlight transformative that may play refining oncology sustaining efficacy amidst growing demands.

Language: Английский

Citations

9

Harnessing Artificial Intelligence to Enhance Global Breast Cancer Care: A Scoping Review of Applications, Outcomes, and Challenges DOI Open Access
Jolene Li Ling Chia, George He, Kee Yuan Ngiam

et al.

Cancers, Journal Year: 2025, Volume and Issue: 17(2), P. 197 - 197

Published: Jan. 9, 2025

In recent years, Artificial Intelligence (AI) has shown transformative potential in advancing breast cancer care globally. This scoping review seeks to provide a comprehensive overview of AI applications care, examining how they could reshape diagnosis, treatment, and management on worldwide scale discussing both the benefits challenges associated with their adoption. accordance PRISMA-ScR ensuing guidelines reviews, PubMed, Web Science, Cochrane Library, Embase were systematically searched from inception end May 2024. Keywords included "Artificial Intelligence" "Breast Cancer". Original studies based focus narrative synthesis was employed for data extraction interpretation, findings organized into coherent themes. Finally, 84 articles included. The majority conducted developed countries (n = 54). publications last 10 years 83). six main themes screening 32), image detection nodal status 7), AI-assisted histopathology 8), assessing post-neoadjuvant chemotherapy (NACT) response 23), margin assessment 5), as clinical decision support tool 9). been used tools augment treatment decisions multidisciplinary tumor board settings. Overall, demonstrated improved accuracy efficiency; however, most did not report patient-centric outcomes. show promise enhancing diagnostic planning. However, persistent adoption, such quality, algorithm transparency, resource disparities, must be addressed advance field.

Language: Английский

Citations

1

Utility of Artificial Intelligence for Decision Making in Thoracic Multidisciplinary Tumor Boards DOI Open Access
Jon Zabaleta, Borja Aguinagalde, Iker López

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(2), P. 399 - 399

Published: Jan. 10, 2025

Background/Objectives: The aim of this study was to analyze whether the implementation artificial intelligence (AI), specifically Natural Language Processing (NLP) branch developed by OpenAI, could help a thoracic multidisciplinary tumor board (MTB) make decisions if provided with all patient data presented committee and supported accepted clinical practice guidelines. Methods: This is retrospective comparative study. inclusion criteria were defined as patients who at MTB suspicious or first diagnosis non-small-cell lung cancer between January 2023 June 2023. Intervention: GPT 3.5 turbo chat used, providing case summary in proceedings latest SEPAR treatment application asked issue one following recommendations: follow-up, surgery, chemotherapy, radiotherapy, chemoradiotherapy. Statistical analysis: A concordance analysis performed measuring Kappa coefficient evaluate consistency results AI committee's decision. Results: Fifty-two included had an overall 76%, index 0.59 replicability 92.3% for whom it recommended surgery (after repeating cases four times). Conclusions: interesting tool which decision making MTBs.

Language: Английский

Citations

1

Therapy of early breast cancer: current status and perspectives DOI Creative Commons

Nikolas Tauber,

Niklas Amann,

Dominik Dannehl

et al.

Archives of Gynecology and Obstetrics, Journal Year: 2025, Volume and Issue: unknown

Published: April 22, 2025

Language: Английский

Citations

1