Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway DOI
Ke Huang, Jing Fang, Shining Xiao

et al.

Life Sciences, Journal Year: 2024, Volume and Issue: unknown, P. 123341 - 123341

Published: Dec. 1, 2024

Language: Английский

Innovative approaches in the treatment-resistant depression: exploring different therapeutic pathways DOI Creative Commons

Anna Łysik,

Katarzyna Logoń, Aleksandra Szczygieł

et al.

GeroScience, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

Language: Английский

Citations

0
The influence of Transcranial Alternating Current Stimulation on EEG spectral power during subsequent sleep: A Randomized Crossover Study DOI
Yuan Shi, Xin Tian,

Taomei Li

et al.

Sleep Medicine, Journal Year: 2024, Volume and Issue: 126, P. 185 - 193

Published: Dec. 9, 2024

Language: Английский

Citations

1
The effect of transcranial alternating current stimulation on cognitive flexibility and attention of children with intellectual disability: a case report DOI Creative Commons

Zahra Ghahri Lalaklou,

Elahe Haghighat-Manesh,

AmirHossein Montazeri Ghahjavarestani

et al.

Journal of Medical Case Reports, Journal Year: 2024, Volume and Issue: 18(1)

Published: July 5, 2024

Abstract Background Intellectual disability is a neurodevelopmental disorder characterized by significant impairments in intellectual functioning and adaptive behavior. Cognitive flexibility attention are crucial cognitive domains often affected children with disability. This case report explores the novel use of transcranial alternating current stimulation, noninvasive brain stimulation technique, to enhance these functions. The study’s novelty lies its focus on alpha-wave frequency targeting specific Brodmann areas potential sustained impact pediatric population Case presentation study involved two elementary school students, both 7 years old mild disability, one male female, Turkic ethnicity, from Shahid Fahmideh School for Exceptional Children Khosrowshah, Iran. Both participants underwent 2-week intervention daily 20-minute sessions at an (10 Hz), F3 P3. were assessed using Wisconsin Card Sorting Test Clock Test, administered four time points: pre-intervention, week 1, 2, 1 month post-intervention. Statistical analysis showed improvements scores compared baseline, enhancement over time. Conclusion findings this indicate that may be promising improving observed suggest could have meaningful clinical development population. However, further research needed confirm efficacy explore broader applicability long-term effects larger, more diverse populations.

Language: Английский

Citations

0
Cognitive Enhancement in Bipolar Disorder: A Double-Blind, Randomized Controlled Trial Utilizing a Novel DTI-Guided Multimodal Neuro-stimulation Protocol DOI Creative Commons
Minmin Wang, Xiaomei Zhang,

Hetong Zhou

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 27, 2024

Abstract Background Traditional neuromodulation strategies for enhancing cognitive abilities in bipolar disorder (BD) patients have shown promise, yet there remains a need novel intervention modalities to improve therapeutic outcomes. Methods This study introduces multi-modal neuro-stimulaton (MNS) protocol using individualized DTI data identify fiber tracts between the DLPFC and dACC. The highest structural connectivity point is selected as stimulation target, which targeted combination of optimized tACS robot-assisted navigated rTMS. A double-blind randomized controlled trial (Trial registration number: NCT05964777 ) was conducted investigate clinical efficacy this innovative approach on BD patients. One hundred were randomly assigned four groups: Group (Active tACS-Active rTMS (MNS Protocol)), B (Sham rTMS), C tACS-Sham D rTMS). Participants underwent 15 sessions over three weeks. Cognitive assessments (THINC integrated tool) at baseline (Week 0), post-treatment 3), follow-up 8). Results Sixty-six participants completed all sessions. Protocol) showed superior improvements Spotter CRT, TMT, DSST scores compared other groups Week 3, with sustained enhancement CRT 8 ( P < 0.01). Only exhibited significant activation left frontal region post-MNS intervention. MNS well tolerated, no side effects observed. Conclusions DTI-guided multimodal neuro-stimulation mode significantly improves impairments safe Highlights Using DTI-derived neural density determine target sites disorder. Combining sequential function Utilizing individually achieve high-precision transcranial stimulation.

Language: Английский

Citations

0
A bibliometric analysis of transcranial alternating current stimulation DOI Creative Commons

C Z Wu,

Chao Shen, Zhaodi Wang

et al.

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: Aug. 2, 2024

Transcranial alternating current stimulation (tACS) can apply currents of varying intensity to the scalp, modulating cortical excitability and brain activity. tACS is a relatively new neuromodulation intervention that now widely used in clinical practice. Many papers related have been published various journals. However, there are no articles objectively directly introduce development trend research hotspots tACS. Therefore, aim this study use CiteSpace visually analyze recent tACS-related publications, systematically detail summarize trends field, provide valuable information for future research.

Language: Английский

Citations

0
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway DOI
Ke Huang, Jing Fang, Shining Xiao

et al.

Life Sciences, Journal Year: 2024, Volume and Issue: unknown, P. 123341 - 123341

Published: Dec. 1, 2024

Language: Английский

Citations

0