Impact of high-risk of obstructive sleep apnea on chronic cough: Data from the Korea National Health and Nutrition Examination Survey DOI Creative Commons
Tae Hoon Kim, I Re Heo, Ho Cheol Kim

et al.

Research Square (Research Square), Journal Year: 2022, Volume and Issue: unknown

Published: July 1, 2022

Abstract Background: Chronic cough is an extremely common clinical symptom of various diseases. However, the relationship between obstructive sleep apnea (OSA) and chronic in general population has not been sufficiently studied.Methods: Using 2019 Korean National Health Nutrition Examination Survey data, we identified a group at high-risk OSA via STOP-Bang questionnaire determined association by regression model.Results: Of eligible 4,217 participants, 97.1% 2.9% were classified into non-chronic groups, respectively. The had higher scores than those without (2.32 ± 1.38 vs. 2.80 1.39; P <0.001). In OSA, 40.4% 52.0% participants scored ≥ 3 STOP-Bang, depending on absence or presence ( =0.012), independently correlated with impaired lung function (forced expiratory volume one second ≥50–<80% predicted value, =0.001; <50, <0.001), low household income =0.015), (STOP-Bang score 3–4, =0.004; 5–8, Obesity I protective role against occurrence =0.023).Conclusion: A for significant risk factor cough. should be considered when evaluating patients.

Language: Английский

Evaluation and Management of Adults with Obstructive Sleep Apnea Syndrome DOI

Janet J. Lee,

Krishna M. Sundar

Lung, Journal Year: 2021, Volume and Issue: 199(2), P. 87 - 101

Published: March 13, 2021

Language: Английский

Citations

143
OSA and Chronic Respiratory Disease: Mechanisms and Epidemiology DOI Open Access
Brian W. Locke,

Janet J. Lee,

Krishna M. Sundar

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(9), P. 5473 - 5473

Published: April 30, 2022

Obstructive sleep apnea (OSA) is a highly prevalent disorder that has profound implications on the outcomes of patients with chronic lung disease. The hallmark OSA collapse oropharynx resulting in transient reduction airflow, large intrathoracic pressure swings, and intermittent hypoxia hypercapnia. subsequent cytokine-mediated inflammatory cascade, coupled tractional injury, damages lungs may worsen several conditions, including obstructive pulmonary disease, asthma, interstitial hypertension. Further complicating this fragmentation deterioration quality occurs because OSA, which can compound fatigue physical exhaustion often experienced by due to their For many disorders, available evidence suggests prompt recognition treatment sleep-disordered breathing improves life also alter course illness. However, more robust studies are needed truly understand relationship impacts confounding comorbidities such as obesity gastroesophageal reflux Clinicians taking care disease should screen treat for given complex bidirectional

Language: Английский

Citations

47
British Thoracic Society Clinical Statement on chronic cough in adults DOI Open Access
Sean Parker, John A. Smith, Surinder S. Birring

et al.

Thorax, Journal Year: 2023, Volume and Issue: 78(Suppl 6), P. s3 - s19

Published: Dec. 1, 2023

### Terminology, epidemiology and impact Causes of CC Clinical assessment Treatable traits in cough #### Smoking ACEI treatment Airway disease: productive Eosinophilic airway disease

Language: Английский

Citations

37
Is laryngeal hypersensitivity the basis of unexplained or refractory chronic cough? DOI Creative Commons
Krishna M. Sundar, Amanda Stark, Nan Hu

et al.

ERJ Open Research, Journal Year: 2021, Volume and Issue: 7(1), P. 00793 - 2020

Published: Jan. 1, 2021

Refractory chronic cough (RCC) and unexplained (UCC) are common problems seen in primary care subspecialty clinics. The role of hypersensitivity laryngeal dysfunction contributing to the persistence RCC/UCC is not well recognised. Data patients with RCC UCC evaluated 2019 by an interdisciplinary clinic led a pulmonologist speech-language pathology team was reviewed. Patients completed validated questionnaires including Leicester questionnaire (LCQ), voice handicap index (VHI) dyspnoea (DI) at initial encounter. Presence based upon history allotussia hypertussia. Laryngeal diagnosed those paresthesias, throat clearing, abnormalities, upper airway documentation functional or anatomic abnormalities on nasoendoscopy. Of 60 UCC/RCC analysed, 75% were female 85% over 40 years age. Cough documented all multiple triggers occurred patients. 95%, 50% 25% reported dyspnoea, respectively. Significant associations between LCQ VHI DI scores when adjusting for age, sex, ethnicity body mass index. 44 out Hypertussia, UCC. Evaluation can delineate allows appropriate treatment be directed this phenotype.

Language: Английский

Citations

33
WAO - ARIA consensus on chronic cough: Executive summary DOI Creative Commons
Philip W. Rouadi, Samar Idriss, Jean Bousquet

et al.

World Allergy Organization Journal, Journal Year: 2025, Volume and Issue: 18(3), P. 101034 - 101034

Published: Feb. 24, 2025

Language: Английский

Citations

0
Cough in the Elderly During the COVID-19 Pandemic DOI Creative Commons
Johanna Kaulamo, Anne M. Lätti, Heikki Koskela

et al.

Lung, Journal Year: 2022, Volume and Issue: 200(2), P. 161 - 168

Published: March 17, 2022

Abstract Introduction The prevalence of chronic cough increases with age. However, data on the and background disorders subtypes in elderly are scarce. objective this study was to identify point risk factors acute, subacute, an community-based population. Methods This a cross-sectional email survey amongst 26,205 members Finnish Pensioners’ Federation during COVID-19 pandemic spring 2021. Results response rate 23.6% (6189). 5983 subjects aged at least 64 years were included analyses (mean 72.6 years, 66.3% female). daily 1.4%, 0.7%, 9.6%, respectively. Only 0.4% had infection. In multivariate analyses, rhinosinusitis, obstructive sleep apnoea common for all subtypes. Chronic several factors; Bronchiectasis (OR 5.79 (CI95% 2.70–12.41)), current asthma (2.67 (2.02–3.54)), rhinosinusitis (2.51 (1.94–3.24)), somatic symptom score (1.13 per (1.07–1.19)), family history (1.88 (1.54–2.30)), gastro-oesophageal reflux disease (1.86 (1.50–2.32)), advanced age (1.20 decade (1.02–1.40)), pulmonary (1.74 (0.99–3.05)), dog ownership (1.42 (1.07–1.89)), (1.41 (1.16–1.73)). Conclusion Acute subacute cough, as well previous infection, uncommon higher than that previously found younger adults. is multifactorial disorder elderly.

Language: Английский

Citations

13
Positive airway pressure treatment affects respiratory symptoms and gastro-oesophageal reflux: the Icelandic Sleep Apnea Cohort Study DOI Creative Commons
Össur Ingi Emilsson, Thor Aspelund, Christer Janson

et al.

ERJ Open Research, Journal Year: 2023, Volume and Issue: 9(5), P. 00387 - 2023

Published: Aug. 31, 2023

Aim To study the effect of positive airway pressure (PAP) treatment on nocturnal gastro-oesophageal reflux (nGOR) and respiratory symptoms among clinical obstructive sleep apnoea (OSA) patients. Methods 822 patients newly diagnosed with OSA referred for PAP were recruited. 732 had a 2-year follow-up visit continuous compliance data (366 full users, 366 partial/non-PAP users). They answered questionnaires, including reporting nGOR, general health. Patients nGOR once week or more defined as “with nGOR”. Those without medication “no Others “possible Results At follow-up, users resulted in decreased (adjusted OR 0.58, 95% CI 0.40–0.86) wheezing 0.56, 0.35–0.88) compared users. Decreased both partial/non-users treatment, was associated decrease productive morning cough 4.70, 2.22–9.99) chronic bronchitis 3.86, 1.74–8.58), but not 0.90, 0.39–2.08). A mediation analysis found that directly led to wheezing, mediated through nGOR. Conversely, Conclusion In an unselected group patients, 2 years symptoms. The itself less wheezing. cough.

Language: Английский

Citations

7
Chronic Cough and Obstructive Sleep Apnea DOI
Krishna M. Sundar, Amanda Stark, Peter V. Dicpinigaitis

et al.

Sleep Medicine Clinics, Journal Year: 2024, Volume and Issue: 19(2), P. 239 - 251

Published: March 12, 2024

Language: Английский

Citations

2
Cough detection using a non-contact microphone: A nocturnal cough study DOI Creative Commons
Marina Eni, Valeria Mordoh, Yaniv Zigel

et al.

PLoS ONE, Journal Year: 2022, Volume and Issue: 17(1), P. e0262240 - e0262240

Published: Jan. 19, 2022

An automatic non-contact cough detector designed especially for night audio recordings that can distinguish coughs from snores and other sounds is presented. Two different classifiers were implemented tested: a Gaussian Mixture Model (GMM) Deep Neural Network (DNN). The detected analyzed compared in sleep stages terms of severity Obstructive Sleep Apnea (OSA), along with age, Body Mass Index (BMI), gender. database was composed nocturnal signals 89 subjects recorded during polysomnography study. DNN-based system outperformed the GMM-based system, at 99.8% accuracy, sensitivity specificity 86.1% 99.9%, respectively (Positive Predictive Value (PPV) 78.4%). Cough events significantly more frequent wakefulness than (p < 0.0001) less deep 0.0001). A positive correlation found between BMI number (R = 0.232, p 0.05), OSA men 0.278, 0.05). This detection may thus be to track progression respiratory illnesses test reactions medications even when contact sensor uncomfortable or infeasible.

Language: Английский

Citations

10
Non-pharmacological Management of Non-productive Chronic Cough in Adults: A Systematic Review DOI Creative Commons
Ana Maria Ilicic, Ana Oliveira,

Razanne Habash

et al.

Frontiers in Rehabilitation Sciences, Journal Year: 2022, Volume and Issue: 3

Published: May 26, 2022

Chronic cough is a common reason for medical referral and its prevalence on the rise. With only one pharmaceutical therapy currently under review treatment of refractory chronic cough, exploring non-pharmacological management therapies important. This systematic summarizes effectiveness in adults with non-productive or due to respiratory diseases.We searched Medline, Embase, Cochrane, CINAHL, Scopus from inception September 2021. Randomized controlled trials published English, Portuguese, French, examining effects (>8 weeks; <2 teaspoons sputum) were included. Mean differences, medians, odds ratios calculated as appropriate.16,546 articles identified six representing five unique studies Studies evaluated 228 individuals disease [162 women (71%); 52 ± 11 61 8 years old]. Obstructive sleep apnea was studied. Non-pharmacological included education, suppression, breathing techniques, mindfulness, continuous positive airway pressure. When standing alone, improved cough-specific health related quality life when not associated interventions (mean diff MD 1.53 4.54), frequency (MD 0.59 95%CI 0.36 0.95), voice outcomes 0.3 1) compared control interventions.The evidence limited. Existing reflect heterogeneity study design, sample size, outcome measures. Thus, clinical recommendations using most effective remain be confirmed.

Language: Английский

Citations

10