Journal of Agricultural and Food Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 6, 2024
Fungal
secondary
metabolites
have
been
increasingly
sought
after
as
an
alternative
strategy
to
herbicides
and
a
source
of
new
medicines.
Twenty
spirobisnaphthalenes
(SBNs)
were
isolated
from
the
fermentation
broth
Edenia
sp.
YUD20003
herb
Drymaria
cordata
(L.)
Willd.
in
China,
including
eight
SBNs
(1–8)
phenolic
dinaphthoether
(9).
Their
chemical
structures
absolute
configurations
elucidated
on
basis
comprehensive
spectroscopic
analyses.
The
biosynthetic
pathway
these
was
proposed.
insight
into
biological
activity
showed
that
not
only
demonstrated
significant
cytotoxicity
against
five
human
cancer
cell
lines
but
also
exhibited
potent
antimicrobial
activities
both
Candida
albicans
Staphylococcus
aureus.
Notably,
3,
5–7,
9
inhibitory
effect
acetylcholinesterase
par
with
tacrine.
Additionally,
compound
7
effectively
inhibited
germination
weed
Setaria
viridis,
suggesting
its
potential
herbicide.
research
highlights
bioactive
natural
products
agrochemical
pharmaceutical
applications.
Mycologia,
Journal Year:
2024,
Volume and Issue:
116(3), P. 355 - 369
Published: April 4, 2024
The
discovery
of
bioactive
compounds
from
fungal
natural
sources
holds
immense
potential
for
the
development
novel
therapeutics.
present
study
investigates
extracts
soil-borne
Penicillium
notatum
and
rhizosphere-inhabiting
Aspergillus
flavus
their
antibacterial,
antifungal,
cytotoxic
potential.
Additionally,
two
were
purified
using
chromatographic
spectroscopic
techniques.
results
demonstrated
that
ethyl
acetate
fraction
A.
exhibited
prominent
activity
against
Artemia
salina,
whereas
P.
displayed
promising
antibacterial
At
dose
concentrations
10,
100,
1000
µg
mL−1,
showed
mortality
percentages
7.6%,
66.4%,
90%,
respectively.
extract
significant
activity,
forming
inhibition
zones
measuring
41,
38,
34,
30
mm
B.
subtilis,
S.
flexneri,
E.
coli,
K.
pneumoniae,
aureus,
respectively,
at
mL−1.
this
concentration,
28,
27,
15
recorded
vulgaris,
typhi,
X.
oryzae.
Using
bioassay-guided
approach,
one
compound
each
was
extracts.
initial
purification
involved
mass
analysis,
followed
by
structural
elucidation
500
MHz
nuclear
magnetic
resonance
(NMR)
spectroscopy.
Compound
1,
derived
flavus,
identified
as
2-hydroxy-5,6-dimethyl-4-oxocyclohex-2-ene-1-carboxylate,
with
a
212,
2,
isolated
notatum,
3-amino-2-(cyclopenta-2,4-dien-1-ylamino)-8-methoxy-4H-chromen-4-one,
an
exact
270.
Based
on
bioassay
results,
1
subjected
to
brine
shrimp
lethality
assay
2
tested
its
30%
larvae
concentration
100
mL−1
increased
70%.
notable
potential,
30,
24,
19,
12
In
comparison,
standard
antibiotic
tetracycline
produced
18,
15,
10
respective
bacterial
strains
same
concentration.
Microbial Cell Factories,
Journal Year:
2024,
Volume and Issue:
23(1)
Published: Aug. 10, 2024
Endophytic
fungi
(EF)
reside
within
plants
without
causing
harm
and
provide
benefits
such
as
enhancing
nutrients
producing
bioactive
compounds,
which
improve
the
medicinal
properties
of
host
plants.
Selecting
with
established
for
studying
EF
is
important,
it
allows
a
deeper
understanding
their
influence.
Therefore,
study
aimed
to
investigate
impact
after
inoculating
plant
Perilla
frutescens,
specifically
focusing
on
role
in
properties.
ACS symposium series,
Journal Year:
2024,
Volume and Issue:
unknown, P. 305 - 343
Published: Aug. 21, 2024
Hydrogen's
high
energy
and
water
vapor
combustion
by
products
make
it
a
vital
role
in
the
low-carbon
economy.
A
novel
hydrogen
generation
method
uses
lignocellulosic
waste
residual
biomass
from
plant
cell
walls,
such
as
agricultural
wastes,
forestry
trash,
energy-yielding
crops.
Lignocellulosic
is
abundant
attractive
renewable
source,
reducing
trash
disposal
greenhouse
gas
emissions.
Alternative
technologies,
especially
those
using
resources,
are
needed
to
replace
carbon
emissions
fossil
fuels.
Dark
fermentation,
which
breaks
down
complex
organic
molecules
with
microbes,
makes
viable
source.
It
effectively
generates
supports
circular
economy
concepts
turning
into
resource.
Many
thermochemical
biological
processes
extract
waste.
Research
improving
these
procedures
for
effectiveness
economic
viability.
reduces
provides
sustainable
energy.
Using
assets
boosts
biotechnology,
process
engineering,
integrated
systems
predicted
lower
production
costs,
making
this
more
realistic
environment.
Journal of Agricultural and Food Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 6, 2024
Fungal
secondary
metabolites
have
been
increasingly
sought
after
as
an
alternative
strategy
to
herbicides
and
a
source
of
new
medicines.
Twenty
spirobisnaphthalenes
(SBNs)
were
isolated
from
the
fermentation
broth
Edenia
sp.
YUD20003
herb
Drymaria
cordata
(L.)
Willd.
in
China,
including
eight
SBNs
(1–8)
phenolic
dinaphthoether
(9).
Their
chemical
structures
absolute
configurations
elucidated
on
basis
comprehensive
spectroscopic
analyses.
The
biosynthetic
pathway
these
was
proposed.
insight
into
biological
activity
showed
that
not
only
demonstrated
significant
cytotoxicity
against
five
human
cancer
cell
lines
but
also
exhibited
potent
antimicrobial
activities
both
Candida
albicans
Staphylococcus
aureus.
Notably,
3,
5–7,
9
inhibitory
effect
acetylcholinesterase
par
with
tacrine.
Additionally,
compound
7
effectively
inhibited
germination
weed
Setaria
viridis,
suggesting
its
potential
herbicide.
research
highlights
bioactive
natural
products
agrochemical
pharmaceutical
applications.
