Addiction Biology,
Journal Year:
2024,
Volume and Issue:
29(5)
Published: May 1, 2024
Abstract
Substance
use
disorders
are
characterized
by
inhibition
deficits
related
to
disrupted
connectivity
in
white
matter
pathways,
leading
via
interaction
difficulties
resisting
substance
use.
By
combining
neuroimaging
with
smartphone‐based
ecological
momentary
assessment
(EMA),
we
questioned
how
biomarkers
moderate
predict
Thus,
aimed
assess
integrity
everyday
and
resting‐state
network
identify
multi‐dimensional
predictors
of
Thirty‐eight
patients
treated
for
alcohol,
cannabis
or
tobacco
disorder
completed
1
week
EMA
report
five
times
complete
Stroop
testing
twice
daily.
Before
tracking,
participants
underwent
resting
state
functional
MRI
diffusion
tensor
imaging
(DTI)
scanning.
Regression
analyses
were
conducted
between
mean
performances
whole‐brain
fractional
anisotropy
(FA)
matter.
Moderation
was
FA
within
significant
clusters
as
moderator
the
link
performance
outcome.
Predictions
strength
known
inhibition‐related
networks
assessed
using
mixed
modelling.
Higher
values
anterior
corpus
callosum
bilateral
corona
radiata
predicted
higher
during
stronger
occipital–frontal–cerebellar
regions.
Integrity
these
regions
moderated
inhibitory
control
use,
whereby
predictive
lowest
probability
highest
values.
In
conclusion,
compromised
structural
brain
systems
appears
underlie
impairment
ability
refrain
from
Brain Structure and Function,
Journal Year:
2022,
Volume and Issue:
227(9), P. 3085 - 3098
Published: Nov. 5, 2022
Abstract
Motricity
is
the
most
commonly
affected
ability
after
a
stroke.
While
many
clinical
studies
attempt
to
predict
motor
symptoms
at
different
chronic
time
points
stroke,
longitudinal
acute-to-chronic
remain
scarce.
Taking
advantage
of
recent
advances
in
mapping
brain
disconnections,
we
outcomes
62
patients
assessed
longitudinally
two
weeks,
three
months,
and
one
year
their
Results
indicate
that
disconnection
patterns
accurately
impairments.
However,
leading
impairment
differ
between
three-time
left
right
These
results
were
cross-validated
using
resampling
techniques.
In
sum,
demonstrated
while
some
neuroplasticity
mechanisms
exist
changing
structure–function
relationship,
prevail
when
predicting
NeuroImage,
Journal Year:
2022,
Volume and Issue:
263, P. 119672 - 119672
Published: Oct. 6, 2022
Language
processing
is
a
highly
integrative
function,
intertwining
linguistic
operations
(processing
the
language
code
intentionally
used
for
communication)
and
extra-linguistic
processes
(e.g.,
attention
monitoring,
predictive
inference,
long-term
memory).
This
synergetic
cognitive
architecture
requires
distributed
specialized
neural
substrate.
Brain
systems
have
mainly
been
examined
at
rest.
However,
task-related
functional
connectivity
provides
additional
valuable
information
about
how
processed
when
various
states
are
involved.
We
gathered
thirteen
fMRI
tasks
in
unique
database
of
one
hundred
fifty
neurotypical
adults
(InLang
[Interactive
networks
Language]
database),
providing
opportunity
to
assess
features
across
wide
range
processes.
Using
this
database,
we
applied
network
theory
as
computational
tool
model
connectome
(LANG
atlas).
The
organization
data-driven
neurocognitive
atlas
was
multiple
levels,
uncovering
its
major
components
(or
crucial
subnetworks),
anatomical
correlates.
In
addition,
estimated
reconfiguration
function
demand
(flexibility)
or
several
factors
such
age
gender
(variability).
observed
that
discrete
could
be
specifically
shaped
promote
key
language:
coding-decoding
(Net1),
control-executive
(Net2),
abstract-knowledge
(Net3),
sensorimotor
(Net4)
functions.
these
pivotal
brain
regions
varied
according
nature
process,
gender,
age.
By
accounting
multifaceted
modulating
factors,
study
can
contribute
enriching
refining
existing
models
language.
LANG
also
considered
reference
comparative
clinical
studies
involving
patients
conditions.
Progress in Neurobiology,
Journal Year:
2024,
Volume and Issue:
236, P. 102602 - 102602
Published: April 4, 2024
Language
is
bounded
to
the
left
hemisphere
in
adult
brain
and
functional
lateralization
can
already
be
observed
early
during
development.
Here
we
investigate
whether
this
paralleled
by
a
of
white
matter
structural
language
network.
We
analyze
strength
microstructural
properties
language-related
fiber
tracts
connecting
temporal
frontal
cortices
with
separation
two
dorsal
tracts,
one
targeting
posterior
Broca's
area
(BA44)
precentral
gyrus
(BA6).
In
large
sample
young
children
(3-6
years),
demonstrate
that,
contrast
BA6-targeting
tract,
asymmetry
BA44-targeting
tract
significantly
correlates
locally
different
aspects
While
its
anterior
segment
reflects
age,
associated
children's
skills.
These
findings
fine-grained
structure-to-function
mapping
lateralized
network
go
beyond
our
current
view
human
maturation.
Addiction Biology,
Journal Year:
2024,
Volume and Issue:
29(5)
Published: May 1, 2024
Abstract
Substance
use
disorders
are
characterized
by
inhibition
deficits
related
to
disrupted
connectivity
in
white
matter
pathways,
leading
via
interaction
difficulties
resisting
substance
use.
By
combining
neuroimaging
with
smartphone‐based
ecological
momentary
assessment
(EMA),
we
questioned
how
biomarkers
moderate
predict
Thus,
aimed
assess
integrity
everyday
and
resting‐state
network
identify
multi‐dimensional
predictors
of
Thirty‐eight
patients
treated
for
alcohol,
cannabis
or
tobacco
disorder
completed
1
week
EMA
report
five
times
complete
Stroop
testing
twice
daily.
Before
tracking,
participants
underwent
resting
state
functional
MRI
diffusion
tensor
imaging
(DTI)
scanning.
Regression
analyses
were
conducted
between
mean
performances
whole‐brain
fractional
anisotropy
(FA)
matter.
Moderation
was
FA
within
significant
clusters
as
moderator
the
link
performance
outcome.
Predictions
strength
known
inhibition‐related
networks
assessed
using
mixed
modelling.
Higher
values
anterior
corpus
callosum
bilateral
corona
radiata
predicted
higher
during
stronger
occipital–frontal–cerebellar
regions.
Integrity
these
regions
moderated
inhibitory
control
use,
whereby
predictive
lowest
probability
highest
values.
In
conclusion,
compromised
structural
brain
systems
appears
underlie
impairment
ability
refrain
from
