Heliyon,
Journal Year:
2024,
Volume and Issue:
10(6), P. e27757 - e27757
Published: March 1, 2024
MicroRNAs
(miRNAs)
are
associated
with
certain
types
of
cancer,
tumor
stages,
and
responses
to
treatment,
thus
efficient
methods
required
identify
them
quickly
accurately.
Abnormal
expression
microRNA-191
(miR-191)
has
been
linked
particular
cancers
several
other
health
conditions,
such
as
diabetes
Alzheimer's
disease.
In
this
study,
a
new
dual-biosensor
based
on
the
zirconium
preasodium-based
metal-organic
framework
(Zr/Pr
MOF)
was
developed
for
rapid,
ultrasensitive,
selective
detection
miRNA-191.
The
synthesized
Zr/Pr
MOF
exhibited
peroxidase-like
activity
fluorescence
properties.
Our
dual
method
involves
monitoring
peroxidase
frameworks
(MOFs)
in
presence
miRNAs.
can
catalyze
hydrogen
peroxide
(H
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(25), P. 31895 - 31921
Published: June 13, 2024
Bimetallic-metal
organic
frameworks
(BiM-MOFs)
or
bimetallic
represent
an
innovative
and
promising
class
of
porous
materials,
distinguished
from
traditional
monometallic
MOFs
by
their
incorporation
two
metal
ions
alongside
linkers.
BiM-MOFs,
with
unique
crystal
structure,
physicochemical
properties,
composition,
demonstrate
distinct
advantages
in
the
realm
biochemical
sensing
applications,
displaying
improvements
optical
stability,
selectivity,
sensitivity.
This
comprehensive
review
explores
into
recent
advancements
leveraging
BiM-MOFs
for
fluorescence-based
sensing,
providing
insights
design,
synthesis,
practical
applications
both
chemical
biological
sensing.
Emphasizing
fluorescence
emission
as
a
transduction
mechanism,
aims
to
guide
researchers
maximizing
potential
across
broader
spectrum
investigations.
Furthermore,
it
prospective
research
directions
addresses
challenges,
offering
valuable
perspectives
on
evolving
landscape
probes
rooted
BiM-MOFs.
ACS Materials Letters,
Journal Year:
2024,
Volume and Issue:
6(6), P. 2339 - 2349
Published: May 14, 2024
The
construction
of
a
highly
luminescent,
stable,
and
target-insensitive
internal
reference
signal
is
significant
in
ratiometric
color
tonality
applications.
Improvement
the
antenna
effect,
efficient
mechanism
that
enhances
luminescence
emission
via
sensitization,
an
effective
route
to
obtain
bright
luminescence.
Additionally,
manipulation
crystal
structure
morphology
key
issue
control
reactivity,
especially
metal–organic
frameworks
(MOFs).
In
present
work,
novel
red
emitter
Eu/Zn
bimetal
biligand
MOF
(UoZ-5)
was
synthesized
used
as
signal.
A
dual-antenna
from
triplet
states
(T1)
ligands
5Do
Eu3+
ion,
observed
explained
on
basis
energy
levels.
With
UoZ-5
serving
reference,
blue-emitting
carbon
quantum
dots
(CQDs)
selective
for
Ag+
ions
nonfluorescent
composite,
CQDs@Ag+,
probe
vitamin
B1,
tonality-based
platform
analysis
were
developed.
Lab on a Chip,
Journal Year:
2024,
Volume and Issue:
24(8), P. 2306 - 2316
Published: Jan. 1, 2024
On-site
monitoring
of
ions
in
drinking
water
is
essential
for
safeguarding
public
health,
ensuring
high
quality,
and
preserving
the
ecological
balance
aquatic
ecosystems.
ACS Applied Nano Materials,
Journal Year:
2024,
Volume and Issue:
7(17), P. 20793 - 20803
Published: Aug. 15, 2024
The
conventional
notion
is
that
enzymes,
natural
and
nanozymes,
exhibit
peak
activity
solely
within
defined
psychrophilic
or
thermophilic
conditions.
This
work
challenges
the
by
preparing
a
highly
efficient
oxidase-mimic
of
Ag-based
metal–organic
frameworks
(MOFs)
(referred
to
as
UoZ-3;
UoZ
stands
for
University
Zakho),
which
effectively
in
wide-range
temperatures.
breakthrough
not
only
widens
working
temperature
range
but
also
overcomes
instability
problem
hydrogen
peroxide
limited
use
peroxidase-based
applications.
UoZ-3
showed
lower
Michaelis–Menten
constants
compared
silver
nanoparticles
ions.
Surprisingly,
cold/hot
adapted
nanozyme
exhibited
sensitivity
both
hydrogen-atom
transfer
single-electron
reactions
with
reducing
agents,
encompassing
all
antioxidant
species
are
relevant
physiological
contexts.
Furthermore,
visual-based
platform
integrated
smartphone
was
established
successfully
applied
total
capacity
detection
various
temperatures
breast
cancer
patients.
will
open
an
avenue
research
Red-emitting
metal-organic
frameworks
(MOFs)
are
still
mostly
based
on
the
use
of
lanthanides
or
functionalization
with
red
fluorophores.
However,
production
transition-metal-based
MOFs
red-emitting
is
scarce.
This
work
reports
synthesis
a
novel
dual-state
Zn-based
MOF
(denoted
as
UoZ-7)
capability
to
detect
target
molecules
in
dual
state,
solution,
and
solid
paper.
UoZ-7
gives
strong
emission
when
excited
solution
state
365
nm
ultraviolet
(UV)
lamp
irradiation.
Coordination-induced
mechanism
for
enhancement
restriction
intramolecular
rotation
occurred
ligand
within
framework
structure.
was
successfully
used
tetracycline
(TC)
using
dual-mode
detection,
fluorescence-based
ratiometry,
color
tonality,
TC
adsorb
surface,
yellow-greenish
emerges
due
aggregation-induced
between
UoZ-7.
Concurrently,
inner
filter
effect
diminishes
The
detection
platform
provides
simple
reliable
fast
method
on-site
various
environmental
biomedical
applications.
Moreover,
will
have
further
luminescence-based
