Brazilian Journal of Physics, Journal Year: 2024, Volume and Issue: 54(6)
Published: Sept. 27, 2024
Language: Английский
Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 65, P. 105854 - 105854
Published: July 23, 2024
Language: Английский
Citations
25
European journal of medical research, Journal Year: 2023, Volume and Issue: 28(1)
Published: Aug. 17, 2023
To explore the forewarning immunological indicators during periodontal attachment loss progression in American adults.A total of 5744 participants with were enrolled from National Health and Nutrition Examination Surveys (NHANES) 2009-2014. In which, dependent variable was counts teeth severe (depth probing above 5 mm). Independent variables circulatory indexes, including white blood cells (WBC), Lymphocytes, Monocytes, Neutrophils, Eosinophils, Basophils. The association among examined using multivariable linear regression models, fitting smoothing curves, generalizing additive models.Based on subjects, we found that tended to occur elderly or males accompanied by higher WBC, as well lower poverty-income ratio educational qualification. WBC (above inflection point: 6200 cells/µL) Neutrophils 3300 positively associated each model. On subgroup analyses, stratified sex race, positive correlation stable both men women, all races except blacks (WBC β = - 0.0576, 95% CI 0.1945 0.0793, 0.0527, 0.2285 0.1231).Increasing risk races, blacks.
Language: Английский
Citations
29
Biomedical Physics & Engineering Express, Journal Year: 2024, Volume and Issue: 10(5), P. 052002 - 052002
Published: Aug. 14, 2024
Abstract Purpose . This review aims to highlight current improvements in microfluidic devices designed for digestive cancer simulation. The emphasizes the use of multicellular 3D tissue engineering models understand complicated biology tumor microenvironment (TME) and progression. purpose is develop oncology research improve patients’ lives. Methods analyzes recent on mimicking cancer. It uses tissue-engineered devices, notably organs a chip (OOC), simulate human organ function lab. Cell cultivation modern three-dimensional hydrogel platforms allows precise geometry, biological components, physiological qualities. novel methodologies, key findings, technical progress explain this field’s advances. Results study discusses advances Micro systems with are emphasized. These capture complex biochemical gradients, niche variables, dynamic cell–cell interactions (TME). reveal stomach progression by duplicating TME. Recent discoveries technology have improved our understanding gut biology, as shown review. Conclusion Microfluidic play crucial role modeling furthering research. could transform drug development treatment revealing provides complete summary suggests future field professionals. review’s major goal further medical
Language: Английский
Citations
14
Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(10)
Published: Oct. 1, 2024
ABSTRACT Nanogels represent a significant innovation in the fields of nanotechnology and biomedical engineering, combining properties hydrogels nanoparticles to create versatile platforms for drug delivery, tissue bioimaging, other applications. These nanoscale hydrogels, typically ranging from 10 1000 nm, possess unique characteristics such as high water content, biocompatibility, ability encapsulate both hydrophilic hydrophobic molecules. The review explores synthesis, structural configurations, stimuli‐responsive nature nanogels, highlighting their adaptability targeted including across challenging barriers like blood–brain barrier. Furthermore, paper delves into applications particularly delivery systems, demonstrating potential revolutionize these fields. Despite promising preclinical results, challenges remain translating technologies clinical practice, issues related stability, scalability, regulatory approval. concludes by discussing future perspectives, emphasizing need further research optimize ultimately aiming enhance efficacy safety settings.
Language: Английский
Citations
12
Fibers and Polymers, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 4, 2024
Language: Английский
Citations
8
International Dental Journal, Journal Year: 2024, Volume and Issue: 74(3), P. 500 - 509
Published: April 1, 2024
To study the relationships of serum 25-hydroxyvitamin D [25(OH)D] with dental caries and periodontitis in a general Norwegian adult population. We analysed subsample 1605 participants from Trøndelag Health Study (HUNT) Norway that had 25(OH)D) levels measured HUNT3 (2006-08) oral health assessed HUNT4 Oral (2017-19). Negative binomial Poisson regression models were used to estimate ratios means (RMs; for count outcomes) prevalence (PRs; dichotomous outcomes). Serum 25(OH)D was inversely associated number decayed teeth dose-response gradient (<30.0 nmol/L: RM 1.41, 95% CI 1.07-1.85; 30.0-49.9 1.14, 0.98-1.32 ≥75.0 0.84, 0.67-1.04, as compared 50.0-74.9 nmol/L group, P trend <.001). Each 25 decrease level 15% (RM 1.15, 1.05-1.26) increase mean teeth. <30.0 35% higher severe (PR 1.35, 1.00-1.83). No association observed between natural The present suggested an inverse teeth, <30 this
Language: Английский
Citations
6
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 277, P. 134504 - 134504
Published: Aug. 6, 2024
Language: Английский
Citations
6
Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 169, P. 113037 - 113037
Published: Aug. 30, 2024
Language: Английский
Citations
5
Pathogens, Journal Year: 2023, Volume and Issue: 12(9), P. 1180 - 1180
Published: Sept. 20, 2023
The active form of vitamin D is the hormonally 1,25(OH)2D3 (Vit D) vitamin, which plays an important role in bone biology and host immunity. receptor (VDR) a nuclear ligand-dependent transcription factor expressed by many cells. Ligation VDR VitD regulates wide plethora genes physiologic functions through formation complex Vit D-VDR signaling cascade. influence immune response to microbial infection has been interest researchers. This particularly oral health diseases, as mucosa exposed microbiota, with certain species capable causing disruption homeostasis. In this review, we focus on modulatory roles degenerative disease, periodontitis.
Language: Английский
Citations
10
Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 169, P. 113072 - 113072
Published: Aug. 31, 2024
Language: Английский
Citations
4