Substance Use & Misuse,
Journal Year:
2024,
Volume and Issue:
59(6), P. 962 - 970
Published: Jan. 31, 2024
Purpose:
State-level
prevalence
data
are
used
to
investigate
whether
recreational
cannabis
legalization
moderates
the
mediated
pathway
from
perception
of
low
risk
harm,
use,
use
disorder
(CUD)
treatment
admissions,
among
adolescents
(age
12–17)
in
US.
Methods:
Annual
state
measures
risk,
and
CUD
admissions
between
2008
2019
(N
=
542
state-year
observations)
were
collected
National
Survey
on
Drug
Use
Health
(NSDUH)
Treatment
Episode
Dataset
–
Admissions
(TEDS-A).
A
two-way
fixed
effects
(state
year)
moderated
mediation
model
was
test
indirect
effect
via
use.
Results:
positive
perceiving
as
observed
prior
but
not
afterwards.
After
legalization,
association
with
strengthened,
suppressed,
compared
before
legalization.
Discussion:
Recreational
may
alter
social
acceptability
medical
self-administration
cannabis,
potentially
leading
utilization
decline
even
factors
for
increase.
Linking
advancing
awareness
health
risks
associated
adolescent
promoting
engagement
through
mHealth
approaches
primary
care
providers
key
addressing
potential
challenges
brought
about
by
expanding
Frontiers in Psychiatry,
Journal Year:
2023,
Volume and Issue:
14
Published: March 10, 2023
Legalization
of
cannabis
use
for
non-medical
(recreational)
purposes
is
changing
the
global
landscape.
As
attitudes
toward
become
more
positive
and
prevalence
increases
in
complex
ways,
concerns
emerge
about
potential
increased
cannabis-attributable
harms.
Understanding
who,
why,
when
this
likely
increase
harms
thus
an
important
public
health
priority.
Both
sex
gender
contribute
to
variability
use,
effects,
sex/gender
considerations
are
evaluating
impacts
legalization.
The
goal
narrative
review
broadly
discuss
differences
whether
there
legalization,
why
these
might
exist.
One
our
strongest
conclusions
that
men
have
always
been
than
women,
yet
gap
has
narrowed
over
time,
be
partly
due
existing
evidence
suggests
also
legalization
on
such
as
cannabis-involved
motor
vehicle
collisions
hospitalizations,
though
results
variable.
body
literature
reviewed
focused
almost
exclusively
samples
cisgender
research
participants,
future
should
encourage
inclusion
transgender
gender-diverse
participants.
More
consideration
sex-
gender-based
analysis
long-term
a
clear
The Lancet Public Health,
Journal Year:
2025,
Volume and Issue:
10(2), P. e148 - e159
Published: Feb. 1, 2025
SummaryCannabis
consumption
is
legally
prohibited
in
most
countries
the
world.
Several
are
legalising
cannabis
for
adult
consumption.
It
important
to
monitor
public
health
effects
of
these
policy
changes.
In
this
paper,
we
summarise
evidence
date
on
legalisation
non-medical
use
Canada
and
USA.
We
describe
regulatory
models
legalisation,
changes
products
pricing,
illicit
market,
use,
cannabis-related
physical
mental
harms.
discuss
challenges
assessing
outcomes
emphasise
importance
continuous
rigorous
monitoring
adverse
inform
design
policies
regulations.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(5), P. 861 - 861
Published: Feb. 28, 2025
Objectives/Background:
The
Cannabis
genus
contain
a
mixture
of
cannabinoids
and
other
minor
components
which
have
been
studied
so
far.
In
this
narrative
review,
we
highlight
the
main
aspects
polarized
discussion
between
abuse
toxicity
versus
benefits
compounds
found
in
sativa
plant.
Methods:
We
investigated
databases
such
as
PubMed,
Google
Scholar,
Web
Science
World
Anti-doping
Agency
(WADA)
documents
for
scientific
publications
that
can
elucidate
heated
related
to
negative
addiction,
organ
damage
improved
sports
performance
medical
benefits,
particularly
athletes,
some
are
promising
nutrients.
Results:
Scientific
arguments
bring
forward
harmful
effects
cannabinoids,
ethical
legislative
their
usage
doping
substances
sports.
present
synthesis
metabolism
cannabis
along
with
identification
methods
routine
anti-doping
tests.
Numerous
studies
attest
beneficial
effects,
could
therapeutic
advantage
athletes
case
injuries.
These
recommend
nutrients,
well
potential
pharmacological
agents.
Conclusions
Future
Perspectives:
From
perspective
both
illegal
use
investigators
sport,
there
many
interpretations,
presented
discussed
review.
Despite
recent
on
species,
is
very
little
research
active
especially
large
groups
compared
placebo.
may
complete
current
vision
topic
clarify
hypotheses
launched
discussions
Public
health
advocates
warn
that
the
rapid
growth
of
legal
markets
for
electronic
nicotine
delivery
systems
(ENDS)
may
generate
a
"gateway"
to
marijuana
and
harder
drug
consumption,
particularly
among
teenagers.This
study
is
first
explore
effects
ENDS
taxes
on
substance
use.We
find
one-dollar
increase
in
(2019$)
associated
with
1to-2
percentage
point
decline
teen
use
0.8
reduction
adult
use.This
result
consistent
e-cigarettes
being
economic
complements.We
no
evidence
affect
treatment
admissions
or
consumption
illicit
drugs
other
than
such
as
cocaine,
methamphetamine,
opioids
over
this
sample
period.
Drug and Alcohol Review,
Journal Year:
2023,
Volume and Issue:
42(5), P. 1104 - 1113
Published: March 13, 2023
Abstract
Introduction
Although
there
is
momentum
towards
legalising
adult
recreational
cannabis
use
worldwide,
the
extent
of
youth
cannabis‐related
harm
associated
with
legalisation
still
uncertain.
The
current
study
aimed
to
assess
whether
initial
implementation
Canada's
(via
Cannabis
Act
)
on
17
October
2018
might
be
harm,
as
assessed
by
emergency
department
visits
for
disorders/poisoning.
Methods
We
used
Ontario
and
Alberta,
Canada
data
from
1
April
2015
31
December
2019.
identified
all
disorders/poisoning
(ICD‐10
CA:
F12.X,
T40.7)
(
n
=
13,615),
defined
patients
younger
than
minimum
legal
sales
age
(18
years,
Alberta;
19
Ontario).
Seasonal
Autoregressive
Integrated
Moving
Average
(SARIMA)
models
were
employed
impact
weekly
counts
harms.
Results
final
SARIMA
intervention
(step)
parameter
indicated
a
post‐legalisation
increase
14.7
(95%
confidence
interval
[CI]
5.0;
24.3,
p
<
0.01)
disorder/poisoning
presentations
Ontario/Alberta
settings,
equivalent
an
20.0%
CI
6.2%;
33.9%).
There
was
no
evidence
associations
between
comparison
series
alcohol,
opioid
or
appendicitis
episodes.
Discussion/Conclusion
Our
findings
require
replication
extension
but
are
consistent
possibility
that
in
departments.
Substance Abuse Treatment Prevention and Policy,
Journal Year:
2024,
Volume and Issue:
19(1)
Published: June 17, 2024
Abstract
Background
Canada
legalized
recreational
cannabis
in
2018,
and
one
of
the
primary
objectives
Cannabis
Act
was
to
protect
youth
by
reducing
their
access
providing
public
education.
has
highest
prevalence
use
worldwide,
particularly
among
young
adults
under
age
25.
is
linked
with
many
adverse
effects
for
including
psychosis,
anxiety,
depression,
respiratory
distress,
cannabinoid
hyperemesis
syndrome,
impaired
cognitive
performance.
Despite
high
evolution
policies
globally,
significant
knowledge
research
gaps
remain
regarding
adult
use.
The
aim
this
scoping
review
map
extent,
nature,
range
evidence
available
on
since
its
legalization,
order
strengthen
policies,
services,
treatments,
training,
education
strategies.
Methods
Using
a
framework
developed
Arksey
O’Malley,
along
PRISMA-ScR
guidelines,
we
conducted
rigorous
search
five
academic
databases:
MEDLINE,
Embase,
APA
PsycINFO,
CINAHL
Web
Science
Core
Collection.
We
included
empirical
studies
that
collected
data
after
legalization
(October
2018)
focused
or
<
30.
Two
reviewers
independently
screened
articles
two
stages
extracted
relevant
information
from
meeting
inclusion
criteria.
Results
Of
47
our
criteria,
92%
used
quantitative
methods,
6%
were
qualitative,
2%
mixed-methods
approach.
Over
two-thirds
(68%)
secondary
data.
These
categorized
into
six
focus
areas:
(1)
prevalence,
patterns,
trends,
(2)
cannabis-related
injuries
emergency
department
(ED)
visits,
(3)
rates
patterns
during
pandemic,
(4)
perceptions
use,
(5)
prevention
tools,
(6)
offenses.
Key
findings
reviewed
include
an
increase
18-24-year-olds
post-legalization,
mixed
results
18.
ED
visits
intentional
unintentional
have
increased
children
teens.
Perception
show
mix
concern
normalization
Though
limited,
are
promising
raising
awareness.
A
decline
offenses
noted
study.
highlights
several
gaps,
need
more
qualitative
data,
disaggregation
demographic
intervention
research,
comprehensive
physical
mental
health
impacts
adults.
Conclusion
Maintaining
approach
critical,
This
involves
implementing
strategies
minimize
harms,
enhancing
education,
minimizing
commercialization,
cannabis,
promoting
guidelines
lower-risk
harm
reduction
strategies,
increasing
training
healthcare
providers.
