Clinical Nutrition, Journal Year: 2024, Volume and Issue: 45, P. 31 - 35
Published: Dec. 20, 2024
Language: Английский
Nutrients, Journal Year: 2025, Volume and Issue: 17(6), P. 1085 - 1085
Published: March 20, 2025
Background/Objectives: Celiac disease (CD) is one of the most common chronic autoimmune disorders affecting children worldwide. The aim to explore significance quality life (QOL) research in pediatric CD, highlighting importance assessing both physical and psychosocial aspects well-being. Materials Methods: study used a self-administered questionnaire, which consisted questions on sociodemographic clinical characteristics, as well general assessment QOL by using validated PedsQL™ 4.0. Results: Dietary restrictions were associated with social challenges, reported 43% respondents who indicated their child had experienced exclusion or distress during family gatherings, while 48% encountered difficulties school setting. overall score mean 68.9 (SD = 15.00), median 67.4, ranged from 41.3 100.0, reflecting individual variations perceived Age significant factor influencing children’s interactions experiences within educational settings, likely due increased academic demands, pressures, developmental changes. Conclusions: suggests that significantly influences functioning life, its impact emotional, social, domains comparatively lower.
Language: Английский
Citations
0
Immunity Inflammation and Disease, Journal Year: 2024, Volume and Issue: 12(8)
Published: Aug. 1, 2024
In mammals, amino acid metabolism has evolved to control immune responses. Tryptophan (Trp) is the rarest essential found in food and its be a primary regulatory node of Celiac disease (CeD) developed immunological condition caused by gluten intolerance linked chronic small intestine enteropathy genetically predisposed individuals. Dendritic cells (DCs), serving as bridge between innate adaptive immunities, can influence responses CeD through phenotypic alterations.
Language: Английский
Citations
1
Tissue Barriers, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 3, 2024
Background Fatty acids (FAs) play pivotal roles in modulating inflammatory pathways celiac disease (CD). The present study explored the relationship between serum FAs levels and expression of both pro- anti-inflammatory cytokines adult pediatric patients with CD.
Language: Английский
Citations
1
Nutrients, Journal Year: 2024, Volume and Issue: 16(11), P. 1649 - 1649
Published: May 27, 2024
There is increasing evidence indicating that changes in both the composition and functionality of intestinal microbiome are closely associated with development several chronic inflammatory diseases, celiac disease (CeD) being particularly noteworthy. Thanks to advent culture-independent methodologies, ability identify quantify diverse microbial communities residing within human body has been significantly improved. However, context CeD, a notable challenge lies characterizing specific microbiota present on mucosal surfaces intestine, rather than relying solely fecal samples, which may not fully represent relevant populations. Currently, our comprehension functional importance mucosa-associated (MAM) CeD remains an ongoing field research because limited number available studies have reported few sometimes contradictory results. MAM plays crucial role progression potentially acting as trigger modulator immune response mucosa, given its proximity epithelial cells direct interaction. According this background, review aims consolidate existing literature specifically focused CeD. By elucidating complex interplay between host system gut microbiota, we aim pave way for new interventions based novel therapeutic targets diagnostic biomarkers
Language: Английский
Citations
0
Clinical Nutrition, Journal Year: 2024, Volume and Issue: 45, P. 31 - 35
Published: Dec. 20, 2024
Language: Английский
Citations
0