Comparison of Serum Zn, Cu, Mg, Mn, Cr, and Fe Levels in Iraqi COVID-19 Patients and their Association with Infection Severity

Indian Journal of Clinical Biochemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 6, 2024

Language: Английский

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Assessment of Supplementation with Different Biomolecules in the Prevention and Treatment of COVID-19

Nutrients, Journal Year: 2024, Volume and Issue: 16(18), P. 3070 - 3070

Published: Sept. 11, 2024

Consequences of the disease produced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have led to an urgent search for preventive and therapeutic strategies. Besides drug treatments, proposals been made supplementation with biomolecules possessing immunomodulatory antioxidant properties. The objective this study was review published evidence on clinical usefulness vitamin D, vitamins (vitamin A, E, C), melatonin, lactoferrin natural products found in food (curcumin, luteolin, ginger, allicin, magnesium zinc) as supplements SARS-CoV-2 infection. In general, conventional treatments these has improve symptoms severity (COVID-19), some indications a effect. conclusion, compounds may assist preventing and/or improving COVID-19. Nevertheless, only limited is available, findings inconsistent. Further investigations are needed verify potential supplements.

Language: Английский

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Suboptimal Consumption of Relevant Immune System Micronutrients Is Associated with a Worse Impact of COVID-19 in Spanish Populations

Nutrients, Journal Year: 2022, Volume and Issue: 14(11), P. 2254 - 2254

Published: May 27, 2022

Coronavirus disease 2019 (COVID-19) has caused a global health crisis and the factors behind its differential impact on COVID-19 among populations are still being known. Geographical differences in nutrient profile could be relevant factor, especially considering that scientific evidence supports 10 micronutrients essential for proper immune system function. This study aims to evaluate these micronutrient intakes territories of Spain analyze their relationship with epidemiological indicators from first two waves COVID-19, when neither specific vaccines nor drugs had yet come into play. Results showed vitamin D, A, B9, zinc were particularly insufficient Spain. The joint intake four was lower regions highest incidence mortality, particular importance, D. A pattern food consumption associated observed. In conclusion, results show relevance optimal foods rich nutrients system. Therefore, this assessment serve launch dietary recommendations strengthen Spanish better face potential new variants and/or further infectious diseases.

Language: Английский

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The concentrations of essential/toxic elements in serum of COVID-19 patients are not directly related to the severity of the disease

Journal of Trace Elements in Medicine and Biology, Journal Year: 2023, Volume and Issue: 78, P. 127160 - 127160

Published: March 27, 2023

In recent months, the current COVID-19 pandemic has generated thousands of studies directly or indirectly related with this disease and/or coronavirus SARS-CoV-2 causing infection. On August 22, 2022, database PUBMED included 287,639 publications containing term COVID-19. However, in spite importance trace elements human health, including immune system, data on levels metals/metalloids patients is very limited.The concentrations As, Cd, Cr, Cu, Hg, Fe, Mg, Mn, Pb, Se, V and Zn were determined by inductively coupled plasma-mass spectrometry (ICP-MS) 126 serum samples individuals infected SARS-CoV-2, as well 88 non-infected individuals. Participants divided into four groups: i) positive (COVID-19 +) an asymptomatic infection course; ii) suffering mild COVID-19; iii) severe COVID-19, iv) negative (COVID-19-) (control group). The occurrence analyzed was evaluated along biochemical profile, blood cell counts, lipids, proteins crucial enzymes.Serum V, Pb higher than those control group. Although no significant differences observed between different groups patients, showed a tendency to be showing symptoms being asymptomatic. Arsenic Hg rarely detected, regardless if subjects not. results did not show rest according severity (asymptomatic, severe).In here obtained, we highlight need reduce exposure minimize potential adverse health outcomes after other hand, although protective role essential found, Mg Cu

Language: Английский

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Selenium serum levels in patients with SARS-CoV-2 infection: a systematic review and meta-analysis

Journal of Nutritional Science, Journal Year: 2023, Volume and Issue: 12

Published: Jan. 1, 2023

The nutritional status is a determinant of the immune response that promotes cellular homeostasis. In particular, adequate selenium levels lead to better antioxidant and response. aim this work assess whether blood levels, at time SARS-CoV-2 infection, have an impact on development severity COVID-19. A systematic review meta-analysis comparative descriptive studies using MeSH terms, COVID-19 was performed. We searched bibliographic databases up 17 July 2022 in PubMed ScienceDirect. Studies reported data were considered. total 629 articles examined by abstract title, which 595 abstracts read, 38 included 11 meta-analysis. Meta-analysis conducted mean difference (MD) with 95 % confidence interval (CI), heterogeneity tested I2 random factors MD between mortality, morbidity healthy subjects P-value 0⋅05. Selenium higher people compared those patients disease (six studies, effects MD: test for overall effect Z = 3⋅28 (P 0⋅001), 97 CI 28⋅36 (11⋅41-45⋅31), P < 0⋅00001), but without when degree mild, moderate or severe cases. conclusion, active infection had lower than population. More are needed evaluate its clinical through randomised trials.

Language: Английский

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