Supportive Care in Cancer, Journal Year: 2024, Volume and Issue: 33(1)
Published: Dec. 20, 2024
Language: Английский
Supportive Care in Cancer, Journal Year: 2025, Volume and Issue: 33(2)
Published: Feb. 1, 2025
Abstract Purpose A significant number of cancer survivors experience cancer-related cognitive impairment (CRCI), which can impact their ability to think, reason, make decisions, and perform daily actions. In recent years, non-pharmacological interventions for CRCI have gained attention. These include exercise, behavioural therapy, training/remediation, dietary, mind–body, multi-modal/complex interventions. This umbrella review provides a critical overview inform guidelines current practice, identify the most promising interventions, uncover gaps in research literature. Methods systematic reviews was pre-registered on Open Science Framework PROSPERO. Six databases were searched. Systematic (SR) assessing any improve cognition (any type) included. The followed gold-standard recommendations. results narratively synthesised, descriptive statistics effect size ranges calculated. Results Sixty-four ( n = 64) SRs synthesised into four domains. Cognitive training/rehabilitation had strongest evidence efficacy. Physical activity/exercise showed efficacy; however, variability findings considerable. Mind–body psychological/behavioural therapy limited, but there short-term effectiveness. Multi-modal/complex potential improving poorly defined. Conclusions Overall, demonstrated efficacy cancer. There limited intervention characteristics within domains consistently related Three key recommendations are provided future research: (1) adopt harmonisation reporting guidelines; (2) develop definitional research; (3) assess participant associated with positive versus null/negative findings.
Language: Английский
Citations
3
Digital Health, Journal Year: 2025, Volume and Issue: 11
Published: Jan. 1, 2025
Objective Metastatic breast cancer (MBC) is associated with burdensome side effects, including cognitive changes that require ongoing monitoring. Cognitive ecological momentary assessments (EMAs) allow for assessment of individual functioning in natural environments and can be administered via smartphones. Accordingly, we sought to establish the feasibility, reliability, validity a commercially available EMA platform. Methods Using prospective design, clinical psychosocial (cognitive batteries; patient reported outcomes) were collected at baseline, followed by 28-day daily protocol included self-ratings symptoms mobile tests (memory, executive functioning, working memory, processing speed). Satisfaction feedback questions follow-up data collection. Feasibility analyzed using mixed descriptive methods. Test-retest reliability was examined intraclass correlation coefficients (ICCs) each EMA, Pearson's used evaluate convergent between EMAs baseline variables. Results Fifty-one women MBC ( n = 51) completed this study. High satisfaction (median 90%), low burden 19%), high adherence rates (mean 94%), 100% retention rate observed. ICCs function, speed robust (>0.90) ICC memory acceptable (>0.66). Other correlational findings indicated strong all EMAs. Conclusion monitoring 28 days feasible MBC, specific (mobile tests; function self-ratings) demonstrating validity.
Language: Английский
Citations
2
Supportive Care in Cancer, Journal Year: 2025, Volume and Issue: 33(2)
Published: Jan. 24, 2025
Abstract Purpose Cancer-related cognitive impairment (CRCI) can have a profound impact on the lives of cancer survivors. A multitude subjective and objective assessment tools exist to assess presence severity CRCI. However, no purpose-built tool exists unmet needs survivors directly relating This paper details development initial validation Multinational Association Supportive Care in Cancer - Unmet Needs Assessment Cancer-Related Cognitive Impairment Impact (the MASCC COG-IMPACT). Methods multistep mixed-methods measurement approach was taken with strong emphasis co-design. Qualitative interviews were conducted ( n = 32) oncology health professionals 19), followed by modified Delphi survey 29). 22) over two rounds then finalise penultimate version for Four-hundred ninety-one 491) completed COG-IMPACT other established measures inform structural, reliability, validity, acceptability, appropriateness, feasibility analyses. Results The final is 55-item eight subscale including indices: “difficulties” “unmet needs”. found structural convergent discriminant internal consistency, test–retest reliability. also be highly acceptable, appropriate, feasible. Conclusion may facilitate optimal care referral line survivor’s CRCI-related difficulties needs. used explore factors contributors Overall, reliable valid both clinical research settings. supporting materials accessed webpage or via Open Science Framework https://osf.io/5zc3a/ ).
Language: Английский
Citations
2
Journal of Cancer Survivorship, Journal Year: 2025, Volume and Issue: unknown
Published: March 11, 2025
Abstract Purpose Cancer-related cognitive impairment (CRCI) causes a wide range of unmet needs for cancer survivors. It is unknown which clinical, demographic, cognitive, and psychological factors underpin account these various needs. This study aimed to ( ) identify associated with CRCI-related needs, b establish the most pertinent that Methods Four hundred fifty-six n = 456) survivors responded demographic clinical questions, as well measures (MASCC COG-IMPACT), perceived (PROMIS-COG), distress (DASS-21). Descriptive statistics, bivariate correlations, feed-forward multiple regression analyses were completed. Results Cognitive severity r 0.39 0.59; p < 0.01), 0.36 0.58; time since diagnosis − 0.11 0.20; 0.05 0.02) significantly across all domains. Age 0.10 0.22; 0.001 0.03), stage at initial 0.13; 0.04), progressed 0.18; sex 0.12; 0.01; females experiencing greater than males), one or more domains need. accounting R 2 0.245, F (3, 487) 48.96, 0.474, 114.81, 0.001), explaining 24.5% 47.4% variance. Conclusion key in Other variables, while did not provide additional predictive utility. Implications Cancer Survivors The results may inform choice supportive care targets, future strategies, improve people cancer-related impairment.
Language: Английский
Citations
0
Clinical Breast Cancer, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0
Supportive Care in Cancer, Journal Year: 2024, Volume and Issue: 33(1)
Published: Dec. 20, 2024
Language: Английский
Citations
0