Interface Focus, Journal Year: 2024, Volume and Issue: 14(6)

Published: Dec. 6, 2024

Intracranial pressure (ICP) monitoring is crucial in the management of traumatic brain injury (TBI) and other neurological conditions. Elevated ICP or too low intracranial compliance (ICC) can compromise perfusion. Simultaneous ICC needed to optimize patient-specific perfusion pathological Surrogate changes be extracted by analysis pulse wave morphology. Non-invasive, fully passive sensor are needed. This study introduces Archimedes, a novel, passive, non-invasive monitor that utilizes mechanical pulsatile movement eyeball assess waveforms. Preliminary findings indicate high correlation r = [0.919; 0.96] between invasive morphologies, demonstrating device’s potential for accurate waveform monitoring. Additionally, discern changes, providing valuable insights TBI normal tension glaucoma patients according shape measured wave. The k-nearest neighbours algorithm used preliminary studies yielded promising diagnostic performance, with an accuracy 0.89, sensitivity 0.82, specificity 1.0 area under curve 0.91. Ethical approvals ongoing have been secured. Initial results Archimedes real-time safe, cost-effective alternative conventional techniques.

Language: Английский