Insights into Cadmium Uptake and Changes in Morphophysiological and Biochemical Characteristics of Eclipta alba L., Plants Exposed to Elevated Cadmium in Soil DOI
Akanksha Dwivedi, Prince Kumar Singh, Umesh Kumar

et al.

Journal of soil science and plant nutrition, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 20, 2025

Language: Английский

Heavy metals in biological samples of cancer patients: a systematic literature review DOI Creative Commons
Donatella Coradduzza, Antonella Congiargiu, Emanuela Azara

et al.

BioMetals, Journal Year: 2024, Volume and Issue: 37(4), P. 803 - 817

Published: Feb. 12, 2024

Abstract The majority of the so-called heavy metals are suspected to be involved in a number pathologies and play role human carcinogenesis. Some them (i.e. arsenic (As), cadmium (Cd), chromium (Cr), lead (Pb), mercury (Hg) nickel (Ni)) have been defined as carcinogens, increasing susceptibility tumor development progression humans. Moreover, Ni, Cr, Cd, Hg, Pb together with zinc (Zn) iron (Fe), may capable stimulating breast cancer reducing patient’s sensitivity treatment through alterations DNA methylation. In patients gastric cancers, levels various augmented hypothesized amplify expression epidermal growth factor receptor type 2 gene. Cd increase risk lung negative impact on overall survival patients. To investigate relation between biological samples risk, occurrence individuals, comprehensive review work was performed, focus breast, lung, prostate cancers. An extensive search strategy devised ensure relevant literature could identified, PECO framework being adopted facilitate this identify key terms. As evidenced review, there is substantial data support hypothesis that influence progression. Unluckily papers dealing determination directly from tissues still rather limited, so we decided expand scope also analyses carried out other samples, urine, plasma, hair, nail, etc. studies reviewed showed several limitations current knowledge gaps present require further investigation improve our comprehension different tumorigenesis. Graphical abstract

Language: Английский

Citations

25

Microwave‐Sintered Nano‐SiC Reinforced 8SiC/Ti‐3Cu Composite: Fabrication, Wear Resistance, Antibacterial Function, and Biocompatibility DOI
Xin Li, Ying‐Chao Zhao, Dengfeng Yin

et al.

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 5, 2025

Abstract The significance of biomedical applications Ti alloys is best emphasized by their widespread utilization as implantable materials, such internal supports and bone replacements. are sensitive to fretting wear, which leads the early failure implants. Improved wear resistance implants essential ensure a prolonged implant life. Based on structure‐function‐integrated concept, this work unprecedentedly designs fabricates an antibacterial 8SiC/Ti‐3Cu composite with improved using microwave sintering from pure Ti, Cu, nano‐SiC powders. For comparison, SiC‐free Ti‐3Cu manufactured under same conditions sintering. addition 8 vol.% SiC significantly reduces porosity pore size composites. shows Vickers hardness 353 HV, compressive strength 803 MPa, elastic modulus 28.7 GPa, increased (wear rate decreased 70% compared Ti‐3Cu). In addition, exhibits excellent electrochemical corrosion resistance, biocompatibility in relation MC3T3‐E1 cells, bacteriostatic over 99% against E. coli . combination wear‐resistant nano‐reinforced 2 Cu renders it highly promising material.

Language: Английский

Citations

2

An Updated Review: Opuntia ficus indica (OFI) Chemistry and Its Diverse Applications DOI Creative Commons
Rizwan Shoukat, Marta Cappai, Giorgio Pia

et al.

Applied Sciences, Journal Year: 2023, Volume and Issue: 13(13), P. 7724 - 7724

Published: June 29, 2023

The beneficial nutrients and biologically active ingredients extracted from plants have received great attention in the prevention treatment of several diseases, including hypercholesterolemic, cancer, diabetes, cardiovascular disorders, hypoglycemic, hypolipidemic, edema, joint pain, weight control, eye vision problems, neuroprotective effects, asthma. Highly predominantly exist fruit cladodes, known as phytochemicals (rich contents minerals, betalains, carbohydrates, vitamins, antioxidants, polyphenols, taurine), which are renowned for their properties relation to human health. Polyphenols widely present demonstrated pharmacological ability through antimicrobial, anti-inflammatory, anti-bacterial, antioxidant capacity, multi-role act Opuntia ficus indica makes it suitable current future usage cosmetics moisturizing, skin improvement, wound care, healthful food essential amino acids, macro micro elements body growth, building materials an eco-friendly sustainable material, a bio-composite, insulator. However, more comprehensive understanding extensive research on diverse array phytochemical cactus pear needed. This review therefore aims gather discuss existing literature chemical composition potential applications extracts, well highlight promising directions this valuable plant.

Language: Английский

Citations

24

Pioneering Role of Nanopore Single-Molecule Sensing in Environmental and Food Surveillance DOI Creative Commons

W. W. Tian,

Xu Wang, Yan Zhang

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(1), P. 41 - 41

Published: Jan. 13, 2025

In recent years, environmental and food safety have garnered substantial focus due to their intimate connection with human health. Numerous biosensors been developed for identifying deleterious compounds; however, these reveal certain limitations. Nanopore sensors, featuring nano-scaled pore size, demonstrated outstanding performance in terms of rapidity, sensitivity, selectivity as a single-molecule technique surveillance. this review, we present comprehensive overview nanopore applications two fields. To elucidate the pioneering roles nanopores, analytes are categorized into three distinct groups, including metal ions, synthetic contaminants, biotoxins. Moreover, variety strategies involved, such coalescence ligand probes, implementation chemical reactions, functionalization etc. These scientific studies showcase versatility diversity technique, paving way further developments technology safety.

Language: Английский

Citations

1

Selenium nanoparticles enhance metabolic and nutritional profile in Phaseolus vulgaris: comparative metabolomic and pathway analysis with selenium selenate DOI Creative Commons
Asmaa Abdelsalam,

Fatma Abd El Lateef Gharib,

Arezue Boroujerdi

et al.

BMC Plant Biology, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 28, 2025

Abstract Selenium is a beneficial element in agriculture, particularly for its potential to improve plant growth and stress tolerance at suitable concentrations. In this study, Phaseolus vulgaris was foliar-sprayed with selenium selenate (Se) or nanoparticles (SeNP) different concentrations during the vegetative stage; afterward, seed yield analyzed metabolomics using 1 H, J -resolved HSQC NMR data, databases. A total of 47 metabolites were identified sugars being major chemical class. control sample, most abundant sugar stachyose (14.6 ± 0.8 mM). Among alkaloids, concentration trigonelline highest (0.6 0.08 Chemometric cluster analyses distinctly differentiated from Se SeNP-treated samples. Treatments SeNP resulted elevated sugars, carboxylic acids, sulfur-containing amino acids compared treated Conversely, betaine levels higher The presence significantly decreased several aliphatic e.g. alanine. addition 50 µM upregulated syringate by 2-fold 1.75-fold, respectively, relative control. Pathway analysis indicated altered pathways due arginine biosynthesis nitrogen metabolism. influenced glyoxylate dicarboxylate metabolism as well glycine-serine threonine This study proved that are more efficient than enhancing metabolic profile which will have implications agricultural practices, focusing on sustainability nutritional enhancement crops.

Language: Английский

Citations

1

In-vitro antioxidant, antidiabetic, anticholinergic activity of iron/copper nanoparticles synthesized using Strobilanthes cordifolia leaf extract DOI Creative Commons
Dharmalingam Kirubakaran,

Kuppusamy Selvam,

Palanisamy Prakash

et al.

OpenNano, Journal Year: 2023, Volume and Issue: 14, P. 100188 - 100188

Published: Sept. 13, 2023

The Strobilanthes cordifolia plant, a member of the Acanthaceae family, has been extensively studied due to its wide range biological properties. This particular research focused on green synthesis FeNPs/CuNPs and evaluated effectiveness experiment through various characterization techniques, including UV, FTIR, XRD, SEM with EDAX. UV analysis provided valuable insights, showing that synthesized nanoparticles had highest absorption values at 462nm for FeNPs 438nm CuNPs. FTIR confirmed presence different functional groups, while XRD measurements validated their crystalline nature. data revealed diverse shapes nanoparticles, rods spherical shapes. Additionally, EDAX Fe Cu elements in biosynthesized nanoparticles. antibacterial activity CuNPs against Staphylococcus aureus Escherichia coli showed significant inhibition. Moreover, demonstrated strong antioxidant activity, as evidenced by effective inhibition DPPH ABTS assays. Their potential anti-diabetic agents was also explored, assessments inhibitory effects α-Amylase α-Glucosidase enzymes. displayed anti-cholinergic enzymes such AChE BChE. Furthermore, comprehensive toxicological studies higher level mosquito larvicidal Aedes aegypti, Anopheles stephensi, Culex quinquefasciatus. Among these, exhibited larval mortality rate 95% Cx. Quinquefasciatus, 93%. In conclusion, this study possess favorable characteristics biomedical applications.

Language: Английский

Citations

22

The Link between Trace Metal Elements and Glucose Metabolism: Evidence from Zinc, Copper, Iron, and Manganese-Mediated Metabolic Regulation DOI Creative Commons
Zhendong Sun,

Yuzhuo Shao,

Kunhao Yan

et al.

Metabolites, Journal Year: 2023, Volume and Issue: 13(10), P. 1048 - 1048

Published: Oct. 2, 2023

Trace metal elements are of vital importance for fundamental biological processes. They function in various metabolic pathways after the long evolution living organisms. Glucose is considered to be one main sources energy that supports activities, and its metabolism tightly regulated by trace such as iron, zinc, copper, manganese. However, there still a lack understanding regulation glucose elements. In particular, underlying mechanism action remains elucidated. this review, we summarize current concepts progress linking metabolism, particularly manganese, iron.

Language: Английский

Citations

21

The Function of Zinc in Animal, Plant, and Human Nutrition DOI Creative Commons

Hamidullah Ozturk,

Parwiz Niazi, Mujibullah Mansoor

et al.

Journal for Research in Applied Sciences and Biotechnology, Journal Year: 2023, Volume and Issue: 2(2), P. 35 - 43

Published: April 8, 2023

Zinc is a crucial micronutrient found in food that essential for the development of all living organisms, it plays vital role gene expression and various physical processes, its deficiency can lead to disease onset reduce crop yield, restrict plant development, lower quality produced goods, zinc also used fertilizers handling metals protect them from oxidation. Additionally, important enhancing human immune system, result hair loss, memory skin disorders, muscular weakness.

Language: Английский

Citations

17

An overview of preconcentration techniques combined with inductively coupled plasma mass spectrometry for trace element determination in biological studies DOI
María N. Oviedo,

Cecilia E. Luján,

Aldana A. Lemos

et al.

Analytical and Bioanalytical Chemistry, Journal Year: 2024, Volume and Issue: 416(11), P. 2641 - 2656

Published: Jan. 20, 2024

Language: Английский

Citations

8

In Vitro Cytotoxicity of Zinc(II) Complexes: Synthesis, Characterization, and Biological Potential DOI

Shazia Nasir Malik,

Areeba Altaf,

Talib H. Mawat

et al.

Chemistry Africa, Journal Year: 2024, Volume and Issue: 7(7), P. 3605 - 3618

Published: June 26, 2024

Language: Английский

Citations

7