Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(11), P. 2341 - 2341
Published: Nov. 16, 2024
Recent
advances
have
highlighted
the
gut
microbiota
as
a
significant
contributor
to
development
and
progression
of
atherosclerosis,
which
is
an
inflammatory
cardiovascular
disease
(CVD)
characterized
by
plaque
buildup
within
arterial
walls.
The
microbiota,
consisting
diverse
collection
microorganisms,
impacts
host's
metabolism,
immune
responses,
lipid
processing,
all
contribute
atherosclerosis.
This
review
explores
complex
mechanisms
through
dysbiosis
promotes
atherogenesis.
We
emphasize
potential
integrating
modulation
with
traditional
care,
offering
holistic
approach
managing
Important
pathways
involve
translocation
microbial
components,
metabolism
metabolites
such
trimethylamine-N-oxide
(TMAO),
production
short-chain
fatty
acids
(SCFAs)
that
influence
vascular
health.
Studies
reveal
distinct
profiles
in
atherosclerosis
patients,
increased
pathogenic
bacteria
(
Microorganisms,
Journal Year:
2025,
Volume and Issue:
13(4), P. 948 - 948
Published: April 20, 2025
Trillions
of
microorganisms
play
a
pivotal
role
in
maintaining
health
and
preventing
disease
humans.
Their
presence
influences
daily
life,
habits,
energy
levels,
pathologies.
The
present
narrative
review
synthesized
recent
studies
microbial
diversity
across
organ
systems.
composition
the
microbiota
regulates
intestinal
barrier,
modulates
immune
response,
metabolism,
produces
essential
compounds
such
as
short-chain
fatty
acids
neurotransmitters.
Dysbiosis
is
associated
with
numerous
pathologies,
including
metabolic,
autoimmune,
neurodegenerative,
cardiovascular
diseases.
key
to
physiological
balance
reducing
risk.
Therapeutic
interventions,
probiotics,
prebiotics,
postbiotics,
microbiome
transplantation,
offer
promising
perspectives
restoring
homeostasis
chronic
npj Science of Food,
Journal Year:
2025,
Volume and Issue:
9(1)
Published: April 22, 2025
Abstract
Recently,
oleogel
and
heat–moisture-treated
(HMT)
modified
starch
have
gained
much
attention
as
a
potential
margarine
replacement
low-digestible
starch,
respectively.
To
date,
most
studies
investigated
HMT
individual
components,
while
information
regarding
their
physiological
properties
food
matrix
form
is
scarce.
Here,
we
demonstrated
that
the
starch-oleogel
exhibited
lowest
plasma
lipid
glucose
levels,
but
high
fecal
excretion
in
mice,
indicating
possibly
lowered
carbohydrate
digestibility.
The
resistant
(RS)
content
was
markedly
decreased
matrix,
suggesting
other
factors,
such
barriers
gel
viscosity,
lowering
food-matrix
Roseburia
,
Adlercreutzia
rc4-4
were
enriched,
Bifidobacterium
Clostridium
reduced
group.
present
study
provides
insights
into
vivo
health
benefits
of
forms.
Clinical Microbiology Reviews,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 22, 2025
SUMMARY
Recent
advances
in
therapeutic
probiotics
have
shown
promising
results
across
various
health
conditions,
reflecting
a
growing
understanding
of
the
human
microbiome’s
role
and
disease.
However,
comprehensive
reviews
integrating
diverse
effects
subjects
been
limited.
By
analyzing
randomized
controlled
trials
(RCTs)
meta-analyses,
this
review
provides
overview
key
developments
probiotic
interventions
targeting
gut,
liver,
skin,
vaginal,
mental,
oral
health.
Emerging
evidence
supports
efficacy
specific
strains
combinations
treating
wide
range
disorders,
from
gastrointestinal
(GI)
liver
diseases
to
dermatological
bacterial
vaginosis,
mental
diseases.
We
discuss
expanding
microbiome-organ
connections
underlying
mechanisms
action.
While
many
clinical
demonstrate
significant
benefits,
we
acknowledge
areas
requiring
further
large-scale
studies
establish
definitive
optimal
treatment
protocols.
The
addresses
challenges
standardizing
research
methodologies
emphasizes
importance
considering
individual
variations
microbiome
composition
host
genetics.
Additionally,
explore
emerging
concepts
such
as
oral-gut-brain
axis
future
directions,
including
high-resolution
profiling,
host-microbe
interaction
studies,
organoid
models,
artificial
intelligence
applications
research.
Overall,
offers
update
on
current
state
multiple
domains
health,
providing
insights
into
directions
potential
for
revolutionize
preventive
medicine.
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(11), P. 2341 - 2341
Published: Nov. 16, 2024
Recent
advances
have
highlighted
the
gut
microbiota
as
a
significant
contributor
to
development
and
progression
of
atherosclerosis,
which
is
an
inflammatory
cardiovascular
disease
(CVD)
characterized
by
plaque
buildup
within
arterial
walls.
The
microbiota,
consisting
diverse
collection
microorganisms,
impacts
host's
metabolism,
immune
responses,
lipid
processing,
all
contribute
atherosclerosis.
This
review
explores
complex
mechanisms
through
dysbiosis
promotes
atherogenesis.
We
emphasize
potential
integrating
modulation
with
traditional
care,
offering
holistic
approach
managing
Important
pathways
involve
translocation
microbial
components,
metabolism
metabolites
such
trimethylamine-N-oxide
(TMAO),
production
short-chain
fatty
acids
(SCFAs)
that
influence
vascular
health.
Studies
reveal
distinct
profiles
in
atherosclerosis
patients,
increased
pathogenic
bacteria
(
