Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: July 27, 2023
Abstract
The
confectionery
industry
is
increasingly
adopting
new
solutions
and
possible
formulations
to
expand
the
ranges
of
chocolate
products
that
support
food
styles
linked
either
cultural
or
health
choices.
chemical-physical
characteristics
chocolates
(dark
milk)
produced
with
traditional
intended
for
vegan
demanding
less
simple
sugars
consumers
(with
a
10%
reduction
in
calorific
value),
were
analysed.
effects
substitution
milk
coconut
copra,
almond
isolated
soy
proteins,
replacement
sucrose
sugars,
stevia
erythritol,
have
been
accounted
by
analysing
texture,
rheology
water
activity,
differential
scanning
calorimetry
(DSC)
fast
field
cycling
(FFC)
nuclear
magnetic
resonance
(NMR)
relaxometry.
plant-based
sample
showed
lower
values
hardness
adhesiveness
texture
analysis,
larger
peak
melting
behaviour
at
DSC.
Moreover,
powder
caused
more
than
halving
yield
stress
similar
decrease
apparent
Casson
viscosity.
crystallisation
cocoa
butter
substituted-sugar
involved
β
V
form,
most
desirable
crystal
form
high-quality
chocolate.
Results
FFC
NMR
relaxometry
allowed
identification
differently
sized
aggregates
whose
chemical
nature
discussed.
data
confirm
those
rheological
DSC
investigations.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(5), P. e26991 - e26991
Published: Feb. 27, 2024
Nonalcoholic
fatty
liver
disease
(NAFLD)
is
a
stress-induced
injury
related
to
heredity,
environmental
exposure
and
the
gut
microbiome
metabolism.
Short-chain
acids
(SCFAs),
metabolites
of
microbiota
(GM),
participate
in
regulation
hepatic
steatosis
inflammation
through
gut-liver
axis,
which
play
an
important
role
alleviation
NAFLD.
However,
little
progress
has
been
made
systematically
elucidating
mechanism
how
SCFAs
improve
NAFLD,
especially
epigenetic
mechanisms
potential
therapeutic
application
as
clinical
treatment
for
Herein,
we
adopted
PubMed
Medline
search
relevant
keywords
such
'SCFAs',
'NAFLD',
'gut
microbiota',
'Epigenetic',
'diet',
'prebiotic
effect'
review
latest
research
on
NAFLD
up
November
2023.
In
this
review,
firstly,
specifically
discussed
production
function
SCFAs,
well
their
crosstalk
coordination
axis.
Secondly,
provided
updated
summary
intensive
discussion
affect
alleviate
from
perspective
genetic
epigenetic.
Thirdly,
paid
attention
pharmacological
physiological
characteristics
proposed
promising
future
direction
adopt
alone
or
combination
with
prebiotics
drugs
prevent
treat
Together,
aimed
elucidate
provide
new
insights
prospects
target
Separations,
Journal Year:
2023,
Volume and Issue:
11(1), P. 2 - 2
Published: Dec. 19, 2023
Monosaccharide
composition
analysis
is
essential
to
the
structural
characterization
and
research
into
biological
activity
of
polysaccharides.
In
this
study,
a
systematic
comparison
was
performed
among
commonly
used
monosaccharide
methods,
including
colorimetric
chromatographic
methods.
These
were
tested
on
16
aldoses,
ketoses,
alditols,
amino
sugars,
uronic
acids.
Furthermore,
effect
hydrolysis
methods
also
investigated.
The
results
showed
that
phenol
sulfuric
acid
method
greatly
affected
by
type
as
reference
substance.
determination
using
carbazole
less
neutral
sugars
than
m-hydroxybiphenyl.
high-performance
thin-layer
chromatography
(HPTLC)
can
simultaneously
analyze
multiple
samples
accurately
determine
acid.
High-performance
liquid
(HPLC)
provide
good
qualitative
quantitative
aldose,
acids,
while
gas
chromatography–mass
spectrometry
(GC-MS)
detect
ketose,
alditols.
Fructose
detected
in
large
amount
inulin
Codonopsis
pilosula
after
one-step
hydrolysis,
it
totally
destroyed
two-step
hydrolysis.
release
galacturonic
significantly
increased
pectin
Lycium
barbarum,
which
indicated
not
enough
for
acidic
study
are
beneficial
selecting
appropriate
order
compositions
natural
Polymers,
Journal Year:
2025,
Volume and Issue:
17(3), P. 412 - 412
Published: Feb. 4, 2025
Inulin
is
a
versatile
biopolymer
that
non-digestible
in
the
upper
alimentary
tract
and
acts
as
bifidogenic
prebiotic
which
selectively
promotes
gut
health
modulates
gut–organ
axes
through
short-chain
fatty
acids
possibly
yet-to-be-known
interactions.
usage
fiber
ingredient
food
has
been
approved
by
FDA
since
June
2018
it
predicted
universal
inulin
market
demand
will
skyrocket
near
future
because
of
its
novel
applications
diseases.
This
comprehensive
review
outlines
known
various
disciplines
ranging
from
medicine
to
industry,
covering
benefits
diseases,
metabolism,
drug
delivery,
therapeutic
pharmacology,
nutrition,
prebiotics
industry.
Furthermore,
this
acknowledges
attention
researchers
knowledge
gaps
regarding
usages
key
modulator
axes.
Frontiers in Pharmacology,
Journal Year:
2025,
Volume and Issue:
16
Published: March 27, 2025
Liver
diseases
are
a
serious
health
problem
worldwide,
especially
with
sustained
increase
in
the
burden
of
it
every
year.
However,
drugs
commonly
used
patients
have
limited
efficacy
and
adverse
reactions
associated
long-term
use.
Therefore,
is
urgent
to
find
effective
safe
alternatives.
Polysaccharides
currently
considered
promising
alternatives
traditional
because
their
extensive
activity
low
toxicity.
This
review
investigated
studies
on
hepatoprotective
polysaccharides
over
past
6
years,
detailing
effects,
potential
mechanisms,
drug
carrier
applications.
These
findings
suggest
that
prominent
preventive
therapeutic
effects
various
liver
such
as
drug-induced
injury,
alcoholic
disease,
hepatitis
B,
non-alcoholic
fatty
fibrosis,
hepatocellular
carcinoma.
Its
mechanism
includes
multiple
aspects
metabolic
regulation,
reduction
oxidative
stress
inflammation,
regulation
gut
microbiota.
Furthermore,
owing
good
physicochemical
properties,
been
applied
delivery
systems
for
chemotherapy
small
molecule
drugs.
further
research
essential
bioavailability,
structure-activity
relationship,
more
clinical
evidence
polysaccharides.
Continued
exploration
will
provide
tremendous
treatment
diseases.
