PLoS ONE,
Journal Year:
2023,
Volume and Issue:
18(8), P. e0289080 - e0289080
Published: Aug. 3, 2023
Severe
mental
illnesses
have
huge
impact
on
health-related
quality
of
life.
They
contribute
to
significant
morbidity
in
terms
number
years
life
lost
form
DALYS
(disability
adjusted
years)
and
shorter
expectancy
early
mortality.
There
is
limited
evidence
their
burden
low-
middle-income
countries
like
Pakistan.To
determine
the
patients
suffering
from
severe
illness
(schizophrenia,
depression,
bipolar
affective
disorder)
demographic
factors
associated
with
poor
health
related
these
patients.This
was
descriptive
cross
sectional,
using
retrospective
record
view
data.
Study
done
under
IMPACT
(Improving
Mental
And
Physical
Together)
Program,
which
conducted
a
multi-morbidity
survey
at
institute
psychiatry,
Benazir
Bhutto
hospital,
Rawalpindi,
EQ
5d
5l
(EURO
QOL
5D5L)
questionnaire
having
both
subjective
(EQVAS)
objective
domains.The
study
included
922
SMI
patients,
whom
555
participants
(60.2%)
were
males
367(39.69%)
females.
The
suffered
major
depressive
disorder
(422;45.8%),
followed
by
(392;
42.51%)
schizophrenia
(108;11.7%).
Most
younger
age
group
(80%)
population
being
below
50
old
had
education
level
secondary
(57.4%).
In
analysis
association
between
EQ-VAS
(subjective
scale)
factors,
found
for
marital
status(p<0.001),
gender
(p<
0.001)
0.001).
Women
lower
scores
(M
=
49.43±SD
27.72)
as
compared
58.81±SD
27.1)
individuals
educational
status
also
mean
scores.
Additionally,
who
single,
divorced
or
widowed
EQVAS
When
analyzed
across
SMI,
it
all
but
significantly
depression
domains
quality-of-life
instrument.Health
an
important
outcome
measure
regular
assessment
aspects
should
be
incorporated
management
plans
illnesses.
Frontiers in Public Health,
Journal Year:
2023,
Volume and Issue:
11
Published: Feb. 16, 2023
Background
People
with
mental
illness
(PWMI)
have
declining
health
related
quality
of
life
(HRQoL),
which
is
frequently
equivalent
to
or
greater
than
that
medical
disorders.
Although,
HRQoL
rapidly
being
recognized
as
an
essential
treatment
outcome
indicator
in
modern
psychiatry,
research
on
the
identification
and
significance
factors
impacting
QoL
PWMI
still
its
early
stages.
Objective
The
aim
this
study
was
identify
predictors
among
people
who
underwent
outpatient
follow-up
Sidama
region,
southern
Ethiopia.
Methods
We
conducted
a
multicenter,
cross-sectional
from
April-1,
May-30,
2022.
A
total
412
participants
took
part
study,
using
interviewer-administered
structured
questionnaire.
measured
12-item
Short-Form
Health
Survey-Version
2
(SF-12v2)
scale.
To
describe
different
variables,
descriptive
statistics
were
employed.
find
independent
predictors,
we
used
multivariable
linear
regression
analysis.
P
-value
<0.05
declared
statistically
significant
at
95%
confidence
interval
(CI).
Result
Out
participants,
nearly
two-third
261
(63.3%)
male
half
203
(49.3%)
diagnosed
schizophrenia.
positively
associated
social
support
(β
=
0.321)
single
2.680).
Conversely,
functional
disability
−0.545),
student
−4.645)
jobless
−3.279)
by
occupation,
depression
−2.839)
negatively
impacted
PWMI.
Conclusion
disorders
significantly
support,
marital
status,
diagnosis
level
disability.
Therefore,
care
system
should
develop
promoting
measures
enhance
functioning,
employment.
Nursing in Critical Care,
Journal Year:
2024,
Volume and Issue:
29(4), P. 807 - 823
Published: April 15, 2024
Abstract
Background
Post‐intensive
care
syndrome
(PICS)
is
characterized
by
all
three
adverse
survivorship
dimensions:
physical
function,
cognitive
function
and
mental
health
status.
Aim
This
review
aimed
to
describe
the
quality
of
life
(QoL)
Intensive
Care
Unit
(ICU)
survivors
with
PICS
after
discharge
their
relatives
Family
(PICS‐F)
report
anxiety,
depression
Post‐Traumatic
Stress
Disorders
(PTSD)
in
studies
investigating
PICS.
Study
Design
A
systematic
was
carried
out.
We
searched
PubMed,
Scopus,
Web
Science
Cumulative
Index
Nursing
Allied
Health
Literature.
registered
PROSPERO
database
(CRD42022382123).
Results
included
19
PICS‐F
this
review.
Fourteen
observational
effects
on
depression,
12
anxiety
nine
post‐traumatic
stress
disorder
10
QoL.
Mobility,
personal
care,
usual
activities
pain/discomfort
QoL
were
domains
most
affected
significant
association
demonstrated
between
a
high
level
ICU
survivors'
levels
relatives'
burden.
Strain‐related
symptoms
sleep
disorders
problems
encountered
PICS‐F.
Conclusion
widespread
experiences
among
relatives,
respectively.
The
results
showed
Relevance
Clinical
Practice
strongly
impact
rehabilitation
process
are
measured
terms
costs,
financial
potentially
preventable
readmission.
BMC Public Health,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: Feb. 4, 2025
Chronic
diseases
are
known
to
detrimentally
impact
an
individual's
quality
of
life
(QOL)
and
well-being.
Therefore,
this
study
aims
evaluate
the
QOL
overall
well-being
among
both
healthy
individuals
those
with
diverse
primary
diagnoses.
This
is
a
cross-sectional
data
collection
took
place
from
May
2022
2023.
Information
regarding
participants
was
gathered
healthcare
workers
without
any
comorbidities.
Data
for
non-healthy
were
collected
diagnosed
various
conditions
across
four
specialist
clinics:
nephrology,
oncology,
psychiatry,
cardiology.
All
completed
Significant
Quality
Life
Measures
(SigQOLM),
comprehensive
assessment
tool
consisting
69
items
that
18
domains
The
included
total
452
participants,
284
(62.8%)
classified
as
healthy.
Among
41
(9.1%)
had
end-stage
renal
(ESRD),
48
(10.6%)
cancer,
40
(8.8%)
depressive
disorder,
remaining
heart
disease
(8.6%).
Statistical
analysis
revealed
significant
differences
(p
<
0.001)
between
in
SigQOLM
scores
all
SigQOLM.
Generally,
also
experienced
excellent
However,
disparities
evident
patients
These
findings
provide
valuable
insights
medical
practitioners
policy
makers
by
enabling
them
tailor
interventions
enhance
their
patients.
Sustainability,
Journal Year:
2024,
Volume and Issue:
16(2), P. 644 - 644
Published: Jan. 11, 2024
This
research
paper
explores
the
intricate
interplay
between
mental
health
(MH),
quality
of
life
(QOL),
religiosity,
and
social
connectedness
among
students
with
disabilities.
In
context
a
growing
awareness
multifaceted
nature
well-being,
this
study
aims
to
unravel
moderating
effects
religiosity
on
relationship
overall
experienced
by
Utilizing
Partial
Least
Squares
Structural
Equation
Modeling
(PLS-SEM),
investigates
direct
within
proposed
conceptual
framework.
The
results
indicate
that
all
disorder
dimensions
(stress,
depression,
anxiety)
negatively
significantly
affect
disabilities;
moreover,
negative
impact
stress
QOL
is
dampened
moderation
effect
connectedness.
Similarly,
anxiety
religiosity.
However,
findings
fails
dampen
depression
(and
(β
=
−0.12))
QOL.
reveal
unable
These
findings’
implications
extend
theoretical
practical
domains,
informing
interventions
support
systems
aimed
at
enhancing
people
Brain Sciences,
Journal Year:
2023,
Volume and Issue:
13(11), P. 1577 - 1577
Published: Nov. 10, 2023
Pharmacological
antipsychotic
drug
interventions
represent
the
cornerstone
of
management
patients
with
schizophrenia
and
other
psychotic
spectrum
disorders.
The
choice
“best”
treatment
should
be
made
on
basis
several
clinical
domains.
However,
despite
available
treatments,
quality
life
reported
by
taking
antipsychotics
is
still
very
poor,
this
outcome
rarely
taken
into
account
in
trials
assessing
efficacy
effectiveness
treatments.
Therefore,
we
performed
a
systematic
review
order
to
assess
impact
patients’
life.
In
particular,
aimed
identify
any
differences
improvement
according
(a)
type
formulation
drugs
(i.e.,
oral
vs.
depot
long-acting
injectable);
(b)
(first
second
third
generation);
(c)
characteristics.
One
hundred
eleven
papers
were
included
review.
main
findings
as
follows:
(1)
usually
considered
secondary
drugs;
(2)
second-generation
have
more
positive
effect
life;
(3)
injectable
are
associated
stable
good
safety
tolerability
profile.
Our
confirms
that
represents
central
element
for
selecting
appropriate
people
schizophrenia.
availability
new
treatments
better
profile,
proven
cognitive
social
functioning,
blood
concentration
might
strategy
improving
European Journal of Human Genetics,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 10, 2024
The
notion
of
a
"serious"
genetic
condition
is
commonly
used
in
clinical
contexts,
laws,
and
policies
to
define
delineate
both
the
permissibility
and,
access
to,
reproductive
genomic
technologies.
Yet,
lacks
conceptual
operational
clarity,
which
can
lead
its
inconsistent
appraisal
application.
A
common
understanding
relevant
considerations
lacking.
This
article
addresses
this
gap.
We
begin
by
outlining
existing
distinctions
around
that
will
factor
into
need
be
navigated,
context
prenatal
testing
use
These
include
tensions
between
care
population
health;
impact
categorizing
as
"serious";
role
perception
quality
life.
then
propose
set
four
core
dimensions
procedural
elements
serve
tool
prompt
mapping
features
seriousness
any
given
context.
Ultimately,
consideration
these
may
improvements
consistency
decision-making
where
pivotal
component
at
policy
practice
level.
Scientific Reports,
Journal Year:
2022,
Volume and Issue:
12(1)
Published: May 12, 2022
In
psychiatry,
recent
years
have
seen
a
change
of
focus
from
clinician-
to
patient-centered
perspective
that
emphasizes
quality
life
as
treatment
target.
As
complex
construct,
is
composed
multiple
dimensions
interact
with
one-another
(e.g.
physical
and
psychological
well-being,
relationships,
autonomy,
self-esteem).
Here,
we
used
data
the
REHABase
cohort,
which
includes
N
=
2180
patients
15
psychosocial
rehabilitation
centers
in
France,
explore
networks
quality-of-life
among
six
psychiatric
disorders:
schizophrenia,
neurodevelopmental,
bipolar,
depressive,
anxiety,
personality
disorders.
Stronger
connections
(edges)
involved
Self-Esteem
dimension,
such
Self-Esteem-Physical
Well-Being,
Self-Esteem-Autonomy,
Self-Esteem-Psychological
Self-Esteem-Resilience.
Self-esteem
was
also
consistently
retrieved
most
central
node
(the
dimension
within
each
network).
Between-group
tests
did
not
reveal
any
differences
regarding
network
structure,
overall
connectivity,
edge-weights,
nodes'
centrality.
Despite
presenting
different
symptom
profiles,
various
disorders
may
demonstrate
similar
inter-relationships
dimensions.
particular,
self-esteem
crucial
inter-connecting
role
patients'
life.
Our
findings
could
support
programmes
specifically
target
improve
cost-effective
way.
Nutrition Reviews,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 17, 2024
Abstract
Context
Childhood
and
adolescence
are
periods
of
critical
importance
in
the
development
mental
health
disorders.
The
Mediterranean
diet
(MD)
has
been
linked
to
multiple
positive
outcomes,
including
reduced
incidence
disorders
fewer
psychiatric
symptoms.
Objective
This
study
aimed
investigate
association
between
adherence
an
MD
outcomes
children
adolescents.
Methods
A
systematic
literature
review
was
conducted
original
research
that
explored
relationship
symptoms
or
MD.
search
on
PubMed,
Scopus,
Web
Science,
MEDES,
Dialnet,
Latindex
from
inception
November
2022,
Newcastle-Ottawa
Scale
used
evaluate
quality
studies.
Results
total
13
studies
(6
cross-sectional,
4
case-control,
2
randomized
clinical
trials,
1
longitudinal
cohort)
out
450
met
inclusion
criteria.
3058
adolescents
with
a
mean
age
range
8.6
16.2
years
were
included.
Among
reviewed
studies,
5
(71.42%)
those
looking
at
attention-deficit/hyperactivity
disorder,
(80%)
examining
depression,
(50%)
assessing
anxiety
found
significant
protective
association.
Seven
articles
(53.84%)
be
high
6
(46.15%)
moderate
quality.
Conclusion
Adherence
could
factor
for
child
adolescent
populations.
suggests
promoting
help
prevent
onset
symptoms,
reduce
symptom
severity,
improve
prognosis
young
patients.
Systematic
Review
Registration
PROSPERO
registration
no.
CRD42021276316.
Journal of Patient-Reported Outcomes,
Journal Year:
2025,
Volume and Issue:
9(1)
Published: Jan. 9, 2025
Abstract
Background
Patient-reported
outcomes
measures
(PROMs)
are
standardized
self-administered
tools
that
assess
the
patient’s
opinion
on
level
of
health,
quality
life,
and
disability
among
other
aspects.
The
objective
this
study
was
to
gather
information
physical
mental
health
in
patients
with
major
illness
using
PROMs.
Methods
This
an
observational,
naturalistic,
prospective
carried
out
adult
stabilized
outpatients
attended
at
nine
Adult
Mental
Health
Centers
Barcelona,
Spain.
All
participants
had
a
confirmed
diagnosis
depression
disorder
or
schizophrenia
(DSM-5)
were
currently
drug
treatment.
Participants
(
n
=
508)
self-completed
baseline
questionnaire
for
clinical
data
PROMs
scales
(PHQ-19,
SF-12,
WHODAS
2.0)
9
months
thereafter
482).
Results
Mean
(SD)
age
50.9
(13.2)
years,
83%
lived
their
families.
Although
93.9%
recognized
having
illness,
15.7%
did
not
know
diagnosis.
When
asked
if
they
considered
during
last
year
treatment
offered
some
type
improvement,
83.9%
answered
affirmatively.
Patients
reported
degree
adherence
high
(77%)
most
them
(80%)
believed
medication
beneficial
effect.
Depressed
showed
both
follow
up
significantly
more
depressive
symptoms
than
group
schizophrenia.
In
group,
statistically
significant
improvement
noted
follow-up.
We
find
differences
within
between
groups
life
(SF-12
scores)
obtained
after
follow-up
Both
follow-up,
higher
(WHODAS
those
Conclusions
can
be
used
real-world
conditions
severity
disease,
present
results
relevant
clinicians.
Advances in Clinical and Experimental Medicine,
Journal Year:
2025,
Volume and Issue:
34(7), P. 0 - 0
Published: Jan. 24, 2025
Background.Psychosocial
interventions
encompass
psychotherapy
and
psychological
education
that
explicitly
target
psychosocial
adaptation.These
have
been
shown
to
a
substantial
positive
effect
on
reducing
anxiety
depression,
as
well
improving
overall
quality
of
life
(QoL).Nevertheless,
there
is
still
no
consensus
concerning
the
therapeutic
effectiveness
these
interventions.Objectives.An
umbrella
review
systematic
reviews
meta-analyses
was
conducted
determine
efficacy
in
QoL
wellbeing
patients
with
cancer
mental
illness.
Materials
methods.A
comprehensive
literature
search
across
multiple
databases,
namely
PubMed,
Embase,
Scopus,
Cochrane
Library.Assessing
Methodological
Quality
Systematic
Reviews
2
(AMSTAR-2)
used
evaluate
research
methodological
rigor.Results.The
12
papers
analyzed
this
explored
therapy
for
psychiatric
patients.The
included
covered
total
8,198
studies.The
AMSTAR-2
rated
8
studies
high-quality
4
intermediate.A
369
examined
cancer,
166
schizophrenia
165
psychoses.Psychological
improved
psychosis
by
1.87,
1.48
1.61,
respectively.Psychiatric
anxiety,
sleep
issues
lower
QoL.This
study
showed
both
groups
patients.Conclusions.Psychological
appears
improve
illness
patients'
wellbeing.Most
evidence
from
high-and
middle-income
nations.Therefore,
further
covers
larger
geographical
area
rigorous
complete
needed
gain
useful
insights
field.