Impact of severe mental illnesses on health-related quality of life among patients attending the Institute of Psychiatry, Rawalpindi from 2019 to 2021: A cross-sectional study DOI Creative Commons
Zarnain Umar,

Zona Tahir,

Asad Tamizuddin Nizami

et al.

PLoS ONE, Journal Year: 2023, Volume and Issue: 18(8), P. e0289080 - e0289080

Published: Aug. 3, 2023

Severe mental illnesses have huge impact on health-related quality of life. They contribute to significant morbidity in terms number years life lost form DALYS (disability adjusted years) and shorter expectancy early mortality. There is limited evidence their burden low- middle-income countries like Pakistan.To determine the patients suffering from severe illness (schizophrenia, depression, bipolar affective disorder) demographic factors associated with poor health related these patients.This was descriptive cross sectional, using retrospective record view data. Study done under IMPACT (Improving Mental And Physical Together) Program, which conducted a multi-morbidity survey at institute psychiatry, Benazir Bhutto hospital, Rawalpindi, EQ 5d 5l (EURO QOL 5D5L) questionnaire having both subjective (EQVAS) objective domains.The study included 922 SMI patients, whom 555 participants (60.2%) were males 367(39.69%) females. The suffered major depressive disorder (422;45.8%), followed by (392; 42.51%) schizophrenia (108;11.7%). Most younger age group (80%) population being below 50 old had education level secondary (57.4%). In analysis association between EQ-VAS (subjective scale) factors, found for marital status(p<0.001), gender (p< 0.001) 0.001). Women lower scores (M = 49.43±SD 27.72) as compared 58.81±SD 27.1) individuals educational status also mean scores. Additionally, who single, divorced or widowed EQVAS When analyzed across SMI, it all but significantly depression domains quality-of-life instrument.Health an important outcome measure regular assessment aspects should be incorporated management plans illnesses.

Language: Английский

Health related quality of life among people with mental illness: The role of socio-clinical characteristics and level of functional disability DOI Creative Commons
Semira Defar,

Yacob Abraham,

Yared Reta

et al.

Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 11

Published: Feb. 16, 2023

Background People with mental illness (PWMI) have declining health related quality of life (HRQoL), which is frequently equivalent to or greater than that medical disorders. Although, HRQoL rapidly being recognized as an essential treatment outcome indicator in modern psychiatry, research on the identification and significance factors impacting QoL PWMI still its early stages. Objective The aim this study was identify predictors among people who underwent outpatient follow-up Sidama region, southern Ethiopia. Methods We conducted a multicenter, cross-sectional from April-1, May-30, 2022. A total 412 participants took part study, using interviewer-administered structured questionnaire. measured 12-item Short-Form Health Survey-Version 2 (SF-12v2) scale. To describe different variables, descriptive statistics were employed. find independent predictors, we used multivariable linear regression analysis. P -value &lt;0.05 declared statistically significant at 95% confidence interval (CI). Result Out participants, nearly two-third 261 (63.3%) male half 203 (49.3%) diagnosed schizophrenia. positively associated social support (β = 0.321) single 2.680). Conversely, functional disability −0.545), student −4.645) jobless −3.279) by occupation, depression −2.839) negatively impacted PWMI. Conclusion disorders significantly support, marital status, diagnosis level disability. Therefore, care system should develop promoting measures enhance functioning, employment.

Language: Английский

Citations

37

Quality of life in ICU survivors and their relatives with post‐intensive care syndrome: A systematic review DOI
Francesco Gravante, Francesca Trotta,

Salvatore Latina

et al.

Nursing in Critical Care, Journal Year: 2024, Volume and Issue: 29(4), P. 807 - 823

Published: April 15, 2024

Abstract Background Post‐intensive care syndrome (PICS) is characterized by all three adverse survivorship dimensions: physical function, cognitive function and mental health status. Aim This review aimed to describe the quality of life (QoL) Intensive Care Unit (ICU) survivors with PICS after discharge their relatives Family (PICS‐F) report anxiety, depression Post‐Traumatic Stress Disorders (PTSD) in studies investigating PICS. Study Design A systematic was carried out. We searched PubMed, Scopus, Web Science Cumulative Index Nursing Allied Health Literature. registered PROSPERO database (CRD42022382123). Results included 19 PICS‐F this review. Fourteen observational effects on depression, 12 anxiety nine post‐traumatic stress disorder 10 QoL. Mobility, personal care, usual activities pain/discomfort QoL were domains most affected significant association demonstrated between a high level ICU survivors' levels relatives' burden. Strain‐related symptoms sleep disorders problems encountered PICS‐F. Conclusion widespread experiences among relatives, respectively. The results showed Relevance Clinical Practice strongly impact rehabilitation process are measured terms costs, financial potentially preventable readmission.

Language: Английский

Citations

14

Quality of life and overall well-being between healthy individuals and patients with varied clinical diagnoses DOI Creative Commons
Mohamad Adam Bujang, Wei Hong Lai, Xun Ting Tiong

et al.

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 4, 2025

Chronic diseases are known to detrimentally impact an individual's quality of life (QOL) and well-being. Therefore, this study aims evaluate the QOL overall well-being among both healthy individuals those with diverse primary diagnoses. This is a cross-sectional data collection took place from May 2022 2023. Information regarding participants was gathered healthcare workers without any comorbidities. Data for non-healthy were collected diagnosed various conditions across four specialist clinics: nephrology, oncology, psychiatry, cardiology. All completed Significant Quality Life Measures (SigQOLM), comprehensive assessment tool consisting 69 items that 18 domains The included total 452 participants, 284 (62.8%) classified as healthy. Among 41 (9.1%) had end-stage renal (ESRD), 48 (10.6%) cancer, 40 (8.8%) depressive disorder, remaining heart disease (8.6%). Statistical analysis revealed significant differences (p < 0.001) between in SigQOLM scores all SigQOLM. Generally, also experienced excellent However, disparities evident patients These findings provide valuable insights medical practitioners policy makers by enabling them tailor interventions enhance their patients.

Language: Английский

Citations

1

Mental Health and Quality of Life among University Students with Disabilities: The Moderating Role of Religiosity and Social Connectedness DOI Open Access

Ebrahim A. Al-Shaer,

Meqbel Aliedan,

Mohamed A. Zayed

et al.

Sustainability, Journal Year: 2024, Volume and Issue: 16(2), P. 644 - 644

Published: Jan. 11, 2024

This research paper explores the intricate interplay between mental health (MH), quality of life (QOL), religiosity, and social connectedness among students with disabilities. In context a growing awareness multifaceted nature well-being, this study aims to unravel moderating effects religiosity on relationship overall experienced by Utilizing Partial Least Squares Structural Equation Modeling (PLS-SEM), investigates direct within proposed conceptual framework. The results indicate that all disorder dimensions (stress, depression, anxiety) negatively significantly affect disabilities; moreover, negative impact stress QOL is dampened moderation effect connectedness. Similarly, anxiety religiosity. However, findings fails dampen depression (and (β = −0.12)) QOL. reveal unable These findings’ implications extend theoretical practical domains, informing interventions support systems aimed at enhancing people

Language: Английский

Citations

7

A Systematic Review on the Effectiveness of Antipsychotic Drugs on the Quality of Life of Patients with Schizophrenia DOI Creative Commons
Gaia Sampogna, Matteo Di Vincenzo,

Luigi Giuliani

et al.

Brain Sciences, Journal Year: 2023, Volume and Issue: 13(11), P. 1577 - 1577

Published: Nov. 10, 2023

Pharmacological antipsychotic drug interventions represent the cornerstone of management patients with schizophrenia and other psychotic spectrum disorders. The choice “best” treatment should be made on basis several clinical domains. However, despite available treatments, quality life reported by taking antipsychotics is still very poor, this outcome rarely taken into account in trials assessing efficacy effectiveness treatments. Therefore, we performed a systematic review order to assess impact patients’ life. In particular, aimed identify any differences improvement according (a) type formulation drugs (i.e., oral vs. depot long-acting injectable); (b) (first second third generation); (c) characteristics. One hundred eleven papers were included review. main findings as follows: (1) usually considered secondary drugs; (2) second-generation have more positive effect life; (3) injectable are associated stable good safety tolerability profile. Our confirms that represents central element for selecting appropriate people schizophrenia. availability new treatments better profile, proven cognitive social functioning, blood concentration might strategy improving

Language: Английский

Citations

16

Unpacking the notion of “serious” genetic conditions: towards implementation in reproductive decision-making? DOI Creative Commons

Erika Kleiderman,

Felicity Boardman, Ainsley J. Newson

et al.

European Journal of Human Genetics, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 10, 2024

The notion of a "serious" genetic condition is commonly used in clinical contexts, laws, and policies to define delineate both the permissibility and, access to, reproductive genomic technologies. Yet, lacks conceptual operational clarity, which can lead its inconsistent appraisal application. A common understanding relevant considerations lacking. This article addresses this gap. We begin by outlining existing distinctions around that will factor into need be navigated, context prenatal testing use These include tensions between care population health; impact categorizing as "serious"; role perception quality life. then propose set four core dimensions procedural elements serve tool prompt mapping features seriousness any given context. Ultimately, consideration these may improvements consistency decision-making where pivotal component at policy practice level.

Language: Английский

Citations

5

The central role of self-esteem in the quality of life of patients with mental disorders DOI Creative Commons
Guillaume Barbalat, Julien Plasse,

Emmanuel Gauthier

et al.

Scientific Reports, Journal Year: 2022, Volume and Issue: 12(1)

Published: May 12, 2022

In psychiatry, recent years have seen a change of focus from clinician- to patient-centered perspective that emphasizes quality life as treatment target. As complex construct, is composed multiple dimensions interact with one-another (e.g. physical and psychological well-being, relationships, autonomy, self-esteem). Here, we used data the REHABase cohort, which includes N = 2180 patients 15 psychosocial rehabilitation centers in France, explore networks quality-of-life among six psychiatric disorders: schizophrenia, neurodevelopmental, bipolar, depressive, anxiety, personality disorders. Stronger connections (edges) involved Self-Esteem dimension, such Self-Esteem-Physical Well-Being, Self-Esteem-Autonomy, Self-Esteem-Psychological Self-Esteem-Resilience. Self-esteem was also consistently retrieved most central node (the dimension within each network). Between-group tests did not reveal any differences regarding network structure, overall connectivity, edge-weights, nodes' centrality. Despite presenting different symptom profiles, various disorders may demonstrate similar inter-relationships dimensions. particular, self-esteem crucial inter-connecting role patients' life. Our findings could support programmes specifically target improve cost-effective way.

Language: Английский

Citations

19

Mediterranean Diet and Mental Health in Children and Adolescents: A Systematic Review DOI
Patricia Camprodon-Boadas,

Aitana Gil-Dominguez,

Elena de la Serna

et al.

Nutrition Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: May 17, 2024

Abstract Context Childhood and adolescence are periods of critical importance in the development mental health disorders. The Mediterranean diet (MD) has been linked to multiple positive outcomes, including reduced incidence disorders fewer psychiatric symptoms. Objective This study aimed investigate association between adherence an MD outcomes children adolescents. Methods A systematic literature review was conducted original research that explored relationship symptoms or MD. search on PubMed, Scopus, Web Science, MEDES, Dialnet, Latindex from inception November 2022, Newcastle-Ottawa Scale used evaluate quality studies. Results total 13 studies (6 cross-sectional, 4 case-control, 2 randomized clinical trials, 1 longitudinal cohort) out 450 met inclusion criteria. 3058 adolescents with a mean age range 8.6 16.2 years were included. Among reviewed studies, 5 (71.42%) those looking at attention-deficit/hyperactivity disorder, (80%) examining depression, (50%) assessing anxiety found significant protective association. Seven articles (53.84%) be high 6 (46.15%) moderate quality. Conclusion Adherence could factor for child adolescent populations. suggests promoting help prevent onset symptoms, reduce symptom severity, improve prognosis young patients. Systematic Review Registration PROSPERO registration no. CRD42021276316.

Language: Английский

Citations

4

Patient-reported outcome measures to assess mental and physical health status, functionality, and quality of life in patients with major depression or schizophrenia DOI Creative Commons
Luís San, Belén Arranz,

C. Romans

et al.

Journal of Patient-Reported Outcomes, Journal Year: 2025, Volume and Issue: 9(1)

Published: Jan. 9, 2025

Abstract Background Patient-reported outcomes measures (PROMs) are standardized self-administered tools that assess the patient’s opinion on level of health, quality life, and disability among other aspects. The objective this study was to gather information physical mental health in patients with major illness using PROMs. Methods This an observational, naturalistic, prospective carried out adult stabilized outpatients attended at nine Adult Mental Health Centers Barcelona, Spain. All participants had a confirmed diagnosis depression disorder or schizophrenia (DSM-5) were currently drug treatment. Participants ( n = 508) self-completed baseline questionnaire for clinical data PROMs scales (PHQ-19, SF-12, WHODAS 2.0) 9 months thereafter 482). Results Mean (SD) age 50.9 (13.2) years, 83% lived their families. Although 93.9% recognized having illness, 15.7% did not know diagnosis. When asked if they considered during last year treatment offered some type improvement, 83.9% answered affirmatively. Patients reported degree adherence high (77%) most them (80%) believed medication beneficial effect. Depressed showed both follow up significantly more depressive symptoms than group schizophrenia. In group, statistically significant improvement noted follow-up. We find differences within between groups life (SF-12 scores) obtained after follow-up Both follow-up, higher (WHODAS those Conclusions can be used real-world conditions severity disease, present results relevant clinicians.

Language: Английский

Citations

0

Assessing the efficacy of psychological interventions in enhancing the quality of life of patients diagnosed with cancer and psychiatric disorders: An umbrella analysis DOI Creative Commons
Hong Guo, Yang Yang

Advances in Clinical and Experimental Medicine, Journal Year: 2025, Volume and Issue: 34(7), P. 0 - 0

Published: Jan. 24, 2025

Background.Psychosocial interventions encompass psychotherapy and psychological education that explicitly target psychosocial adaptation.These have been shown to a substantial positive effect on reducing anxiety depression, as well improving overall quality of life (QoL).Nevertheless, there is still no consensus concerning the therapeutic effectiveness these interventions.Objectives.An umbrella review systematic reviews meta-analyses was conducted determine efficacy in QoL wellbeing patients with cancer mental illness. Materials methods.A comprehensive literature search across multiple databases, namely PubMed, Embase, Scopus, Cochrane Library.Assessing Methodological Quality Systematic Reviews 2 (AMSTAR-2) used evaluate research methodological rigor.Results.The 12 papers analyzed this explored therapy for psychiatric patients.The included covered total 8,198 studies.The AMSTAR-2 rated 8 studies high-quality 4 intermediate.A 369 examined cancer, 166 schizophrenia 165 psychoses.Psychological improved psychosis by 1.87, 1.48 1.61, respectively.Psychiatric anxiety, sleep issues lower QoL.This study showed both groups patients.Conclusions.Psychological appears improve illness patients' wellbeing.Most evidence from high-and middle-income nations.Therefore, further covers larger geographical area rigorous complete needed gain useful insights field.

Language: Английский

Citations

0