Perspectives of gene editing for cattle farming in tropical and subtropical regions

Animal Reproduction, Journal Year: 2022, Volume and Issue: 19(4)

Published: Jan. 1, 2022

Cattle productivity in tropical and subtropical regions can be severely affected by the environment. Reproductive performance, milk meat production are compromised heat stress imposed elevated temperature humidity. The resulting low contributes to reduce farmer's income increase methane emissions per unit of animal protein produced pressure on land usage. introduction highly productive European cattle breeds as well crossbreeding with local have been adopted strategies but positive effects limited adaptation animals hot climates reduction heterosis effect following generations. Gene editing tools allow precise modifications genome an ally industry regions. Alleles associated or tolerance shifted between without need crossbreeding. Alongside assisted reproductive biotechnologies selection, gene accelerate genetic gain indigenous such zebu cattle. This review focuses some potential applications for farming regions, bringing aspects related stress, yield, bull reproduction emissions.

Language: Английский

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Folic Acid and Taurine Alleviate the Impairment of Redox Status, Immunity, Rumen Microbial Composition and Fermentation of Lambs under Heat Stress

Animals, Journal Year: 2024, Volume and Issue: 14(7), P. 998 - 998

Published: March 25, 2024

The aim of this study was to investigate if the supplementation folic acid and taurine can relieve adverse effects different levels heat stress (HS) on growth performance, physiological indices, antioxidative capacity, immunity, rumen fermentation microbiota. A total 24 Dorper × Hu crossbred lambs (27.51 ± 0.96 kg) were divided into four groups: control group (C, 25 °C), moderate HS (MHS, 35 severe (SHS, 40 treatment group, under (RHS, °C, 4 mg/kg BW/d coated taurine, respectively). Results showed that, compared with Group C, significantly decreased ADG (p < 0.05), in RHS markedly higher than MHS SHS 0.05). had significant detrimental indices immune status 4th day such as RR ST, increased 0.05) level induced increase MDA, TNF-α, IL-β, decrease T-AOC, SOD, GPx, IL-10, IL-13, IgA, IgG, IgM However, there a improvement these after HS. Moreover, Quinella Succinivibrio, an evident genera Rikenellaceae_RC9_gut_group Asteroleplasma LEfSe analysis that Butyrivibrio, Eubacterium_ventriosum_group, f_Bifidobacteriaceae enriched MHS, groups, respectively. Correlated indicated genus positively associated while it negatively involved IgM, SOD 0.05); Anaeroplasma propionate valerate, Succinivibrio TNF-α In conclusion, may alleviate antioxidant immunomodulation, by inducing changes microbiome improve animal performance.

Language: Английский

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Effects of Transport Duration and Pre-Transport Fasting on Blood Biochemistry in Dorper × Mongolian Sheep

Animals, Journal Year: 2024, Volume and Issue: 14(10), P. 1482 - 1482

Published: May 16, 2024

Transport is a high-risk time for sheep, especially if the distances are long and sheep fasted beforehand. Two experiments were conducted to compare transport durations of 1 hour (1 h) 3 hours (3 effects feeding before using Dorper × Mongolian which typical region may be tolerant high temperatures in Inner summer. Thirty 4-month-old male randomly divided into two treatment groups, with 15 sheep/treatment each experiment, evaluate on blood biochemical indicators, stress hormone levels, rectal temperatures, antioxidant status lambs In Experiment 1, levels triglycerides free fatty acids after h significantly lower than (p < 0.05). The thyroxine malondialdehyde greater Creatine kinase tended = 0.051). 2, urea superoxide dismutase group pre-transport was those fed serum cortisol level higher compared 0.04). Total capacity that 0.0001). We conclude reduction nutritional transported longer without feed suggests transporting hot conditions northern China fasting period should restricted. However, decrease induced by following worthy further study.

Language: Английский

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Heat stress has divergent effects on the milk microbiota of Holstein and Brown Swiss cows.

Journal of Dairy Science, Journal Year: 2024, Volume and Issue: unknown

Published: June 1, 2024

Heat stress (HS) is one of the pivotal causes economic losses in dairy industries and affects welfare performance, but its effect on milk microbiota remains elusive. It also unclear if how different breeds may cope with HS sustaining productive performance. The objectives this study were to compare a) performance 2 breeds, namely Holstein Brown Swiss, subjected b) effects thermal comfort conditions HS. was carried out 36 cows, 18 per breed. induced by switching off cooling system during a natural heat wave for 4 d. Besides Temperature Humidity Index (THI), animal confirmed measuring respiratory frequency rectal temperature twice daily at a.m. 3 p.m. differently impacted breeds. Rectal temperatures higher while no changes found Swiss. Milk yield recording sampling performed morning milking d 1 (at 4.00 a.m.) afternoon 5.00 p.m.). Productive parameters different: yield, fat-corrected milk, energy-corrected protein casein content, renneting decreased remained unaffected modified differently. During HS, Swiss richer (α diversity) than one. Comparing time points before within showed that less affected Holstein's. Under same condition, did not discriminate between Holstein. Consistently α β diversity, number operational taxonomic units (OTUs) genus level changed their abundance (74 OTUs) (only 20 OTUs). most significant Acinetobacter, Chryseobacterium, Cutibacterium, Enterococcus, Lactococcus, Prevotella-9, Serratia, Streptococcus. In conclusion, present report confirms extends previous studies demonstrating cows regulate body better relative tolerance compared uncultured microbiota, which more evident

Language: Английский

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The effects and mechanisms of heat stress on mammalian oocyte and embryo development

Journal of Thermal Biology, Journal Year: 2024, Volume and Issue: 124, P. 103927 - 103927

Published: Aug. 1, 2024

Language: Английский

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