Pesticides impacts on human health and the environment with their mechanisms of action and possible countermeasures

Heliyon, Journal Year: 2024, Volume and Issue: 10(7), P. e29128 - e29128

Published: April 1, 2024

Pesticides are chemical constituents used to prevent or control pests, including insects, rodents, fungi, weeds, and other unwanted organisms. Despite their advantages in crop production disease management, the use of pesticides poses significant hazards environment public health. Pesticide elements have now perpetually entered our atmosphere subsequently contaminated water, food, soil, leading health threats ranging from acute chronic toxicities. can cause toxicity if a high dose is inhaled, ingested, comes into contact with skin eyes, while prolonged recurrent exposure leads toxicity. produce different types toxicity, for instance, neurotoxicity, mutagenicity, carcinogenicity, teratogenicity, endocrine disruption. The pesticide formulation may depend on specific active ingredient presence synergistic inert compounds that enhance modify its Safety concerns need hour contemporary pesticide-induced hazards. effectiveness implementation current legislature providing ample protection human key concerns. This review explored comprehensive summary regarding updated impacts advanced safety legislation. Implementing regulations, proper training, education help mitigate negative promote safer more sustainable agricultural practices.

Language: Английский

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Environmental occurrence, toxicity concerns, and biodegradation of neonicotinoid insecticides

Environmental Research, Journal Year: 2022, Volume and Issue: 218, P. 114953 - 114953

Published: Nov. 28, 2022

Language: Английский

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Ecological impacts and management strategies of pesticide pollution on aquatic life and human beings

Marine Pollution Bulletin, Journal Year: 2024, Volume and Issue: 206, P. 116613 - 116613

Published: July 24, 2024

Language: Английский

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Fipronil insecticide toxicology: oxidative stress and metabolism

Critical Reviews in Toxicology, Journal Year: 2016, Volume and Issue: 46(10), P. 876 - 899

Published: Sept. 19, 2016

Fipronil (FIP) is widely used across the world as a broad-spectrum phenylpyrazole insecticide and veterinary drug. FIP was to act by targeting γ-aminobutyric acid (GABA) receptor has favorable selective toxicity towards insects rather than mammals. However, because of accidental exposure, incorrect use or widespread leading contamination water soil, there increasing evidence that could cause variety toxic effects on animals humans, such neurotoxic, hepatotoxic, nephrotoxic, reproductive, cytotoxic vertebrate invertebrates. In last decade, oxidative stress been suggested be involved in various toxicities induced FIP. To date, few reviews have addressed relation stress. The focus this article primarily intended summarize progress research associated with possible mechanism for FIP-induced well metabolism. present review reports studies conducted reveal generation reactive oxygen species (ROS) result treatment correlated them types toxicity. Furthermore, metabolism also reviewed, during process, CYP450 enzymes were might occur. roles compounds protecting against based their anti-oxidative summarized further understand role

Language: Английский

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Pollinators and Global Food Security: the Need for Holistic Global Stewardship

Food Ethics, Journal Year: 2016, Volume and Issue: 1(1), P. 75 - 91

Published: May 9, 2016

Language: Английский

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