PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(1), P. e0316927 - e0316927
Published: Jan. 8, 2025
Bacterial
vaginosis
(BV)
is
a
prevalent
cause
of
vaginal
symptoms
in
women
reproductive
age.
With
the
widespread
heavy
metal
pollutants
and
their
harmful
function
on
women’s
immune
hormonal
systems,
it
necessary
to
explore
association
between
exposure
BV.
This
study
investigates
potential
relationship
serum
metals
bacterial
cohort
American
women.
The
present
employed
cross-sectional
analysis
2,493
participating
2001–2004
National
Health
Nutrition
Examination
Survey
(NHANES).
Multivariable
logistic
regression
models
were
utilized
assess
correlation
these
variables.
A
stratified
was
performed
investigate
among
different
population
groups
further,
smooth
curve
fittings
conducted
intuitively
evaluate
correlation.
According
current
results,
significant
identified
high
levels
lead
cadmium
likelihood
developing
vaginosis.
We
found
that
(OR
=
1.35,
95%
CI:
1.06–1.72,
p
0.016)
1.41,
1.01–1.98,
0.047)
increased
risk
by
35%
41%,
respectively,
highest
level
group
comparison
lowest
fully
adjusted
model.
Furthermore,
research
discovered
no
statistically
total
mercury
heightened
susceptibility
0.96,
0.75–1.23,
0.763).
Results
our
indicated
an
inverse
risk,
including
cadmium.
Reducing
could
be
vital
preventing
managing
Frontiers in Pharmacology,
Journal Year:
2024,
Volume and Issue:
15
Published: March 19, 2024
Heavy
metals,
common
environmental
pollutants
with
widespread
distribution
hazards
and
several
health
problems
linked
to
them
are
distinguished
from
other
toxic
compounds
by
their
bioaccumulation
in
living
organisms.
They
pollute
the
food
chain
threaten
of
animals.
Biologically,
heavy
metals
exhibit
both
beneficial
harmful
effects.
Certain
essential
such
as
Co,
Mn,
Se,
Zn,
Mg
play
crucial
roles
vital
physiological
processes
trace
amounts,
while
others
like
As,
Pb,
Hg,
Cd,
Cu
widely
recognized
for
properties.
Regardless
functions,
an
excess
intake
all
beyond
tolerance
limit
can
lead
toxicity.
Animals
face
exposure
through
contaminated
feed
water,
primarily
a
result
anthropogenic
pollution.
After
ingestion
persist
body
extended
duration
nature
dictates
whether
they
induce
acute
or
chronic,
clinical
subclinical,
subtle
toxicities.
The
effects
disruption
cellular
homeostasis
generation
free
radicals
that
develop
oxidative
stress.
In
cases
metal
poisoning,
characteristic
symptoms
may
arise,
potentially
culminating
death
animals
corresponding
necropsy
findings.
Chronic
toxicities
manifest
decline
overall
condition
scoring
decrease
production
potential
Elevated
levels
consumable
animal
products
raise
public
concerns.
Timely
diagnosis,
targeted
antidotes,
management
strategies
significantly
mitigate
impact
on
livestock
health,
productivity,
reproductive
performance.
Frontiers in Veterinary Science,
Journal Year:
2023,
Volume and Issue:
10
Published: March 29, 2023
Toxicity
with
heavy
metals
has
proven
to
be
a
significant
hazard
several
health
problems
linked
it.
Heavy
bioaccumulate
in
living
organisms,
pollute
the
food
chain,
and
possibly
threaten
of
animals.
Many
industries,
fertilizers,
traffic,
automobile,
paint,
groundwater,
animal
feed
are
sources
contamination
metals.
Few
metals,
such
as
aluminum
(Al),
may
eliminated
by
elimination
processes,
but
other
like
lead
(Pb),
arsenic
(As),
cadmium
(Ca)
accumulate
body
leading
chronic
toxicity
Even
if
these
have
no
biological
purpose,
their
toxic
effects
still
present
some
form
that
is
damaging
its
appropriate
functioning.
Cadmium
(Cd)
Pb
negative
impacts
on
number
physiological
biochemical
processes
when
exposed
sub-lethal
doses.
The
nephrotoxic
Pb,
As,
Cd
well
known,
high
amounts
naturally
occurring
environmental
occupational
populations
exposures
an
adverse
relationship
between
kidney
damage
metal
exposure.
Metal
determined
absorbed
dosage,
route
exposure,
duration
whether
acute
or
chronic.
This
can
numerous
disorders
also
result
excessive
due
oxidative
stress
generated
free
radical
production.
concentration
decreased
through
various
procedures
including
bioremediation,
pyrolysis,
phytoremediation,
rhizofiltration,
biochar,
thermal
process.
review
discusses
few
mechanisms,
cattle
special
emphasis
kidneys.
Frontiers in Public Health,
Journal Year:
2023,
Volume and Issue:
11
Published: Feb. 14, 2023
Background
Infertility
has
been
confirmed
as
a
significant
medical
and
social
problem.
Heavy
metal
exposure
refers
to
risk
factor
for
infertility,
which
is
capable
of
damaging
the
reproductive
system
males
females.
However,
heavy
female
infertility
have
rarely
investigated.
The
aim
this
study
was
analyze
association
between
infertility.
Methods
A
cross-sectional
using
data
from
three
cycles
National
Health
Nutrition
Examination
Survey
(NHANES,
2013–2018)
performed.
Female
evaluated
by
positive
responses
question
rhq074
in
questionnaire.
Cadmium
(Cd),
lead
(Pb),
mercury
(Hg),
arsenic
(As)
levels
blood
or
urine
were
examined
inductively
coupled
plasma
mass
spectrometry.
correlation
analyzed
through
weighted
logistic
regression.
Results
total
838
American
women
aged
20–44
years
covered
study.
Among
all
participants,
112
(13.37%)
subjected
Urinary
Cd
urinary
As
significantly
higher
infertile
than
control
(
P
<
0.05,
0.05).
showed
with
prevalence
rose
increase
trend
=
0.045).
associated
some
regression
(Crude,
Q2:
OR
3.99,
95%
CI
1.82,
8.74,
Q3:
2.90,
1.42,
5.92.
Model
1,
3.68,
1.64,
8.27,
2.33,
1.13,
4.48.
2,
4.11,
1.63,
10.07,
2.44,
1.07,
5.53.
3,
3.77,
1.52,
9.35).
Moreover,
Pb
(OR
2.16),
1.68,
1.11,
2.55),
1.02,
1.00,
1.03)
positively
correlated
35–44
years.
1.67,
1.16,
2.40,
2.49)
1.54,
2.38)
BMI
≥25
Conclusions
increased
levels.
To
extent,
Blood/urine
related
advanced
age
overweight/obese
women.
results
need
be
further
validated
future
prospective
studies.
Plants,
Journal Year:
2023,
Volume and Issue:
12(3), P. 429 - 429
Published: Jan. 17, 2023
Environmental
contamination
with
a
myriad
of
potentially
toxic
elements
(PTEs)
is
triggered
by
various
natural
and
anthropogenic
activities.
However,
the
industrial
revolution
has
increased
intensity
these
hazardous
their
concentration
in
environment,
which,
turn,
could
provoke
potential
ecological
risks.
Additionally,
most
PTEs
pose
considerable
nuisance
to
human
beings
affect
soil,
aquatic
organisms,
even
nematodes
microbes.
This
comprehensive
review
aims
to:
(i)
introduce
elements;
(ii)
overview
major
sources
environmental
compartments;
(iii)
briefly
highlight
impacts
on
humans,
plants,
life,
health
soil;
(iv)
appraise
methods
for
tackling
PTE-caused
pollution;
(v)
discuss
concept
applications
eco-technological/green
approaches
(comprising
phytoextraction,
rhizofiltration,
phytostabilization,
phytovolatilization,
phytorestoration);
(vi)
role
microbes
phytoremediation
under
PTE
stress;
(vii)
enlighten
genetic
engineering
advancing
varied
PTEs.
Overall,
appropriate
strategies
must
be
developed
order
stop
gene
flow
into
wild
species,
biosafety
issues
properly
addressed.
consistent
efforts
should
undertaken
tackle
(e.g.,
risk
estimation,
understanding,
acceptance
feasibility)
guarantee
successful
implementation
programs,
raise
awareness
this
green
technology
among
laymen,
strengthen
networking
scientists,
stakeholders,
industrialists,
governments
non-government
organizations.
This
chapter
delves
into
the
combined
molecular
toxicity
mechanisms
of
heavy
metal
mixtures,
focusing
on
their
pervasive
presence
due
to
industrial
activities
and
impact
human
health.
The
authors
highlight
significance
bioaccumulation
metals
through
ingestion
inhalation,
which
can
lead
various
health
implications.
highlights
multifaceted
effects
mixtures
cardiovascular
system,
contributing
diseases
like
atherosclerosis
hypertension
oxidative
stress
vascular
inflammation.
It
details
interactions
these
with
proteins,
particularly
inhibition
ATPases
promotion
damage,
leading
dysfunction.
briefly
touches
upon
link
between
cadmium
exposure
prostate
cancer,
emphasizing
need
for
further
investigation
underlying
this
association.
Additionally,
it
mentions
potential
zinc
sulfate
olfactory
neuron
subtypes
in
adult
fish,
suggesting
that
disrupt
sensory
systems
aquatic
organisms.
Moreover,
explores
neurotoxicity
metals,
discussing
nervous
system
neurodevelopmental
disorders.
also
examines
male
female
reproductive
systems,
evidence
disruptions
hormone
levels,
sperm
quality,
fertility.
call
enhanced
monitoring
levels
general
population
better
understand
its
They
emphasize
research
by
contribute
health,
inform
clinical
treatments
public
interventions.
By
highlighting
bioaccumulation,
stress,
time-dependent
responses,
study
sheds
light
urgent
intervention
strategies
mitigate
adverse
environment.