PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(1), P. e0316927 - e0316927
Published: Jan. 8, 2025
Bacterial
vaginosis
(BV)
is
a
prevalent
cause
of
vaginal
symptoms
in
women
reproductive
age.
With
the
widespread
heavy
metal
pollutants
and
their
harmful
function
on
women’s
immune
hormonal
systems,
it
necessary
to
explore
association
between
exposure
BV.
This
study
investigates
potential
relationship
serum
metals
bacterial
cohort
American
women.
The
present
employed
cross-sectional
analysis
2,493
participating
2001–2004
National
Health
Nutrition
Examination
Survey
(NHANES).
Multivariable
logistic
regression
models
were
utilized
assess
correlation
these
variables.
A
stratified
was
performed
investigate
among
different
population
groups
further,
smooth
curve
fittings
conducted
intuitively
evaluate
correlation.
According
current
results,
significant
identified
high
levels
lead
cadmium
likelihood
developing
vaginosis.
We
found
that
(OR
=
1.35,
95%
CI:
1.06–1.72,
p
0.016)
1.41,
1.01–1.98,
0.047)
increased
risk
by
35%
41%,
respectively,
highest
level
group
comparison
lowest
fully
adjusted
model.
Furthermore,
research
discovered
no
statistically
total
mercury
heightened
susceptibility
0.96,
0.75–1.23,
0.763).
Results
our
indicated
an
inverse
risk,
including
cadmium.
Reducing
could
be
vital
preventing
managing
Toxics,
Journal Year:
2023,
Volume and Issue:
11(12), P. 1000 - 1000
Published: Dec. 7, 2023
Reproductive
disorders
are
considered
a
global
health
problem
influenced
by
physiological,
genetic,
environmental,
and
lifestyle
factors.
The
increased
exposure
to
bisphenols,
chemical
used
in
large
quantities
for
the
production
of
polycarbonate
plastics,
has
raised
concerns
regarding
risks
humans,
particularly
their
endocrine-disrupting
effects
on
female
reproductive
health.
To
provide
basis
future
research
environmental
interference
health,
we
reviewed
relevant
studies
patterns
levels
bisphenols
matrices
humans
(including
susceptible
populations
such
as
pregnant
women
children).
In
addition,
focused
Human & Experimental Toxicology,
Journal Year:
2024,
Volume and Issue:
43
Published: Jan. 1, 2024
An
increasing
number
of
studies
have
investigated
the
effects
Cd
on
human
health.
Cd-induced
dermatotoxicity
is
an
important
field
research,
but
numerous
focused
skin.
Moreover,
most
been
performed
using
HaCaT
cells
not
primary
keratinocytes.
In
this
study,
we
provide
results
describing
cytotoxic
exposure
epidermal
keratinocytes
obtained
from
different
donors.
The
subtoxic
concentration
cadmium
chloride
was
determined
via
MTT
assay,
and
transcriptomic
analysis
exposed
to
(25
µM)
performed.
As
in
cells,
resulted
increased
ROS
levels,
cell
cycle
arrest,
induction
apoptosis.
addition,
report
that
affects
zinc
copper
homeostasis,
induces
metallothionein
expression,
activates
various
signaling
pathways,
including
Nrf2,
NF-kB,
TRAIL,
PI3K.
secretion
cytokines
(IL-1,
IL-6,
IL-10,
PGE2)
upregulates
expression
several
cytokeratins,
such
as
KRT6B,
KRT6C,
KRT16,
KRT17.
a
better
understanding
mechanisms
cadmium-induced
cytotoxicity
its
effect
skin
cells.
ChemSusChem,
Journal Year:
2024,
Volume and Issue:
17(11)
Published: Feb. 1, 2024
Abstract
The
improper
and
inadequate
treatment
of
industrial,
agricultural,
household
wastewater
exerts
substantial
pressure
on
the
existing
ecosystem
poses
a
serious
threat
to
health
both
humans
animals.
To
address
these
issues,
different
types
materials
have
been
employed
eradicate
detrimental
pollutants
from
facilitate
reuse
water
resources.
Nevertheless,
owing
challenges
associated
with
degradation
traditional
post‐use
their
incompatibility
environment,
natural
biopolymers
garnered
considerable
interest.
Silk
protein,
as
biomacromolecule,
exhibits
advantageous
characteristics
including
environmental
friendliness,
low
carbon
emissions,
biodegradability,
sustainability,
biocompatibility.
Considering
recent
research
findings,
this
comprehensive
review
outlines
structure
properties
silk
proteins
offers
detailed
overview
manufacturing
techniques
in
production
silk‐based
(SBMs)
spanning
forms.
Furthermore,
it
conducts
an
in‐depth
analysis
state‐of‐the‐art
SBMs
for
purposes,
encompassing
adsorption,
catalysis,
disinfection,
desalination,
biosensing.
highlights
potential
addressing
provides
valuable
insights
into
prospective
avenues
further
research.
PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(1), P. e0316927 - e0316927
Published: Jan. 8, 2025
Bacterial
vaginosis
(BV)
is
a
prevalent
cause
of
vaginal
symptoms
in
women
reproductive
age.
With
the
widespread
heavy
metal
pollutants
and
their
harmful
function
on
women’s
immune
hormonal
systems,
it
necessary
to
explore
association
between
exposure
BV.
This
study
investigates
potential
relationship
serum
metals
bacterial
cohort
American
women.
The
present
employed
cross-sectional
analysis
2,493
participating
2001–2004
National
Health
Nutrition
Examination
Survey
(NHANES).
Multivariable
logistic
regression
models
were
utilized
assess
correlation
these
variables.
A
stratified
was
performed
investigate
among
different
population
groups
further,
smooth
curve
fittings
conducted
intuitively
evaluate
correlation.
According
current
results,
significant
identified
high
levels
lead
cadmium
likelihood
developing
vaginosis.
We
found
that
(OR
=
1.35,
95%
CI:
1.06–1.72,
p
0.016)
1.41,
1.01–1.98,
0.047)
increased
risk
by
35%
41%,
respectively,
highest
level
group
comparison
lowest
fully
adjusted
model.
Furthermore,
research
discovered
no
statistically
total
mercury
heightened
susceptibility
0.96,
0.75–1.23,
0.763).
Results
our
indicated
an
inverse
risk,
including
cadmium.
Reducing
could
be
vital
preventing
managing
