Research Square (Research Square),
Journal Year:
2022,
Volume and Issue:
unknown
Published: Dec. 7, 2022
Abstract
Heterocyclic
aromatic
amines
(HAA)
are
mutagenic
compounds;
however,
their
long-term
effects
on
humans
remain
poorly
studied.
This
study
investigated
the
association
between
HAA
concentration
and
mortality
in
adults.
Data
from
National
Health
Nutrition
Examination
Survey
2013-2014
were
linked
to
data
2019
analyzed
using
Cox
regression
analysis
determine
of
different
with
all-cause,
cardiovascular
disease
(CVD),
cancer
mortality.
Age,
sex,
education
level,
race,
poverty
income
ratio,
body
mass
index,
smoking
status,
drinking
serum
cotinine
included
as
covariates
three
models.
1,713
adults
a
median
age
47
years
(49.5%
men).
During
follow-up
at
71
months,
100
deaths
occurred.
Owing
detection
limits,
only
four
had
discernible
rates
our
analysis.
Among
them,
norharman
was
significantly
associated
all-cause
CVD
The
hazard
ratio
(HR)
1.50
(95%
confidence
interval:
1.10–2.04)
for
when
analyzing
natural
log-transformed
continuous
variable
3.33
2.24–4.95)
Associations
remained
consistent
concentrations
binary
variables
(split
by
median).
Urinary
harman
seemed
show
negative
No
definitive
evidence
found
an
other
is
Frontiers in Public Health,
Journal Year:
2024,
Volume and Issue:
12
Published: March 6, 2024
Available
literature
has
found
an
association
between
firefighting
and
pathologic
pathways
leading
to
cardiorespiratory
diseases,
which
have
been
linked
with
exposure
polycyclic
aromatic
hydrocarbons
(PAHs).
PAHs
are
highlighted
as
priority
pollutants
by
the
European
Human
Biomonitoring
Initiative
in
occupational
non-occupational
contexts.
Lipids in Health and Disease,
Journal Year:
2024,
Volume and Issue:
23(1)
Published: May 27, 2024
Abstract
Background
The
relationships
between
urinary
polycyclic
aromatic
hydrocarbon
(PAH)
metabolites
and
hyperlipidemia
have
not
been
thoroughly
studied.
primary
goal
of
this
research
focused
on
investigating
the
linkage
PAH
metabolite
concentrations
in
urine
prevalence
within
US
adults.
Methods
A
cross-sectional
analysis
was
conducted
using
data
from
2007–2016
National
Health
Nutrition
Examination
Survey
(NHANES).
Logistic
regression
models
were
used
to
assess
correlations
levels
risk
hyperlipidemia,
while
restricted
cubic
spline
examine
dose‒response
relationships.
Subgroup
interaction
analyses
performed
further
elucidate
these
associations.
Weighted
quantile
sum
(WQS)
analyzed
cumulative
impact
various
risk.
Results
This
study
included
7,030
participants.
Notably,
individuals
highest
quintile
exhibited
a
significantly
elevated
even
after
comprehensive
adjustments
(odds
ratio
[OR]:
1.33,
95%
confidence
interval
[CI]:
1.01–1.75).
Moreover,
1-hydroxyphenanthrene
2-hydroxynaphthalene
fourth
2-hydroxyfluorene
third,
fourth,
fifth
quintiles
demonstrated
positive
with
hyperlipidemia.
These
associations
persisted
across
subgroup
analyses.
Additionally,
correlation
mixture
(positive
model:
OR
=
1.04,
CI:
1.00-1.09)
observed
WQS
model,
showed
most
substantial
contribution.
Conclusion
identified
significant
demographic,
being
predominant
influencer.
findings
underscore
need
mitigate
exposure
as
preventive
measure
for
Sustainable Chemistry for the Environment,
Journal Year:
2024,
Volume and Issue:
7, P. 100146 - 100146
Published: Aug. 23, 2024
Polyaromatic
hydrocarbons
(PAHs)
pose
a
global
threat
in
both
developed
and
developing
countries
due
to
their
adverse
effects
on
various
ecosystems.
The
low
molecular
weight
(LMW)
PAHs,
widely
used
everyday
life,
are
potential
contaminants.
Being
highly
volatile,
they
often
uptaken
by
plants
enter
the
food
chain,
necessitating
an
effective
biodegradation
system.
Over
last
decade,
research
has
advanced
significantly
bacterial
of
PAHs
composed
more
than
three
rings.
This
review
focuses
levels
PAH
soils
worldwide
highlights
diverse
communities
found
these
capable
degrading
LMW-PAHs.
It
also
elucidates
mechanisms
LMW-PAH
degradation
bacteria.
Various
studies
indicate
that
while
individual
bacteria
contribute
degradation,
consortia
promise
better
efficiency.
underscores
need
for
further
bioremediation
using
networks
development
methods
targeting
wide
range
In
conclusion,
optimizing
enhancing
environmental
conditions
could
improve
LMW-PAHs,
reducing
ecological
health
impacts.
Environmental Science and Pollution Research,
Journal Year:
2024,
Volume and Issue:
31(42), P. 54339 - 54362
Published: Aug. 29, 2024
Abstract
This
work
presents
an
integrated
overview
of
polycyclic
aromatic
hydrocarbons’
(PAHs)
ubiquity
comprising
environmental
contamination
in
the
air,
aquatic
ecosystems,
and
soils;
characterizes
biota;
identifies
main
biomonitors
human
exposure
to
PAHs
associated
health
risks.
Urban
centers
industrial
areas
present
increased
concentrations
air
(1344.4–12,300
versus
0.03–0.60
ng/m
3
industrial/urban
rural
zones)
soils
(0.14–1.77
×
10
6
2.00–9.04
1.59–5.87
ng/g
urban,
forest,
soils),
respectively.
Increased
were
found
coastal
zones
superficial
waters
as
well
sediments
(7.00
4
–1.00
9
ng/g).
Benzo(a)pyrene,
a
carcinogenic
PAH,
was
all
media.
Mosses,
lichens,
tree
leaves,
bivalves,
cephalopods,
terrestrials’
snails,
honeybees
are
good
biota
contamination.
More
studies
needed
improve
characterization
PAHs’
levels,
distribution,
bioaccumulation
media
assess
risks
for
health.
Actions
strategies
mitigate
prevent
environment
trophic
chains
toward
WHO’s
One-Health
Perspective
promote
ecosystems
life
urgently
needed.
