Selenomethionine modulates the JAK2 / STAT3 / A20 pathway through oxidative stress to alleviate LPS-induced pyroptosis and inflammation in chicken hearts

Biochimica et Biophysica Acta (BBA) - General Subjects, Journal Year: 2024, Volume and Issue: 1868(4), P. 130564 - 130564

Published: Jan. 23, 2024

Language: Английский

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Resveratrol improves emamectin benzoate-induced pyroptosis and inflammation of Ctenopharyngodon idellus hepatic cells by alleviating oxidative stress/endoplasmic reticulum stress

Fish & Shellfish Immunology, Journal Year: 2023, Volume and Issue: 142, P. 109148 - 109148

Published: Oct. 6, 2023

Language: Английский

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HgCl2 exposure mediates pyroptosis of HD11 cells and promotes M1 polarization and the release of inflammatory factors through ROS/Nrf2/NLRP3

Ecotoxicology and Environmental Safety, Journal Year: 2023, Volume and Issue: 269, P. 115779 - 115779

Published: Dec. 6, 2023

Mercury (Hg) is a serious metal environmental pollutant. HgCl

Language: Английский

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Carvacrol Reduces Mercuric Chloride-Induced Testicular Toxicity by Regulating Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Histopathological Changes

Biological Trace Element Research, Journal Year: 2023, Volume and Issue: 202(10), P. 4605 - 4617

Published: Dec. 22, 2023

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Exploring Epigenetic and Genetic Modulation in Animal Responses to Thermal Stress

Molecular Biotechnology, Journal Year: 2024, Volume and Issue: 67(3), P. 942 - 956

Published: March 25, 2024

Language: Английский

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Protective Effects of Syringic Acid Against Oxidative Damage, Apoptosis, Autophagy, Inflammation, Testicular Histopathologic Disorders, and Impaired Sperm Quality in the Testicular Tissue of Rats Induced by Mercuric Chloride

Environmental Toxicology, Journal Year: 2024, Volume and Issue: 39(10), P. 4803 - 4814

Published: Aug. 3, 2024

Mercury (Hg) is one of the most toxic heavy metals that damage testicular tissue. chloride (HgCl

Language: Английский

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Baicalein inhibits apoptosis and autophagy induced by chlorpyrifos exposure to kidney of Cyprinus carpio through activation of PI3K/AKT pathway

Pesticide Biochemistry and Physiology, Journal Year: 2023, Volume and Issue: 196, P. 105624 - 105624

Published: Sept. 16, 2023

Language: Английский

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Coexposure to fluoride and sulfur dioxide aggravates enamel mineralization disorders in mice by disrupting calcium homeostasis-mediated endoplasmic reticulum stress

Food and Chemical Toxicology, Journal Year: 2025, Volume and Issue: unknown, P. 115317 - 115317

Published: Feb. 1, 2025

Language: Английский

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Exploring Stressors: Impact on Cellular Organelles and Implications for Cellular Functions

Stresses, Journal Year: 2025, Volume and Issue: 5(2), P. 26 - 26

Published: April 4, 2025

Cellular stressors have been demonstrated to exert a substantial influence on the functionality of organelles, thereby impacting cellular homeostasis and contributing development disease pathogenesis. This review aims examine impact diverse stressors, including environmental, chemical, biological, physical factors, critical organelles such as cell membrane, mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, membrane-less organelles. The intricate molecular mechanisms underlying stress responses, encompassing oxidative stress, protein misfolding, metabolic reprogramming, capacity elicit adaptive responses or culminate in pathological conditions. interplay between these organelle dysfunction has implicated myriad diseases, neurodegenerative disorders, cancer, immune-related pathologies. A comprehensive understanding by which respond can offer valuable insights into therapeutic strategies aimed at mitigating damage.

Language: Английский

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miR-15b-5p promotes HgCl2-induced chicken embryo kidney cells ferroptosis by targeting β-TrCP-mediated ATF4 ubiquitin degradation

Toxicology, Journal Year: 2024, Volume and Issue: 503, P. 153742 - 153742

Published: Feb. 6, 2024

Language: Английский

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