European Journal of Nutrition & Food Safety,
Journal Year:
2024,
Volume and Issue:
16(5), P. 11 - 31
Published: April 22, 2024
Plastics
released
into
the
environment
can
be
degraded
by
physical
erosion,
biodegradation,
photocatalytic
activity,
and
oxidation,
resulting
in
smaller
plastics
particles.
Microplastics
(MPs)
are
plastic
particles
relatively
than
5
mm
size.
Furthermore,
microplastics
with
particle
sizes
less
1000
or
100
nm
known
as
nano-plastics
(NPs).
The
presence
effect
of
MPs
NPs
human
body
has
not
been
adequately
studies,
thus
we
aim
to
explain
origins
adept,
carefully
explore
pathways
which
enter
system
highlight
impact
on
health.
Major
examples
include
Polyethylene
(PE),
polypropylene
(PP),
polyvinyl
chloride
(PVC),
polyamide
(PA),
polystyrene
(PS),
polyethylene
terephthalate
(PET),
Acrylonitrile-Butadiene-Styrene
(ABS),
polymethyl
methacrylate
(PMMA).
were
found
have
two
sources
(primary
secondary).
primary
materials
purposely
produced
suit
household
industrial
uses,
such
exfoliants
for
skin
care
products,
construction,
packaging
materials.
Secondary
originated
from
decomposition/degradation
large
products
over
time.
plants
(fruits
vegetables),
animals
(fish,
crab,
shrimp,
oysters,
mussels),
water
(taps,
sachet,
bottled
water),
salt,
sugar,
honey.
Plastics'
ecosystem
is
getting
increasingly
severe,
it
imperative
that
proper
attention
paid
this
issue.
vast
number
available
influence
lives
populace
each
geographic
area.
In
review
article,
identified
three
routes
through
gain
entrance
body:
oral
ingestion,
cutaneous
(skin
contact),
inhalation.
investigated
summarized
impacts
most
impacted
organs
included
lungs,
blood,
kidney,
brain,
ovary,
testes,
intestines.
review,
offered
a
viable
solution
includes
use
biodegradable
polymers,
increased
usage
eco-friendly
biotechnology
engineering
solutions,
implementation
regulatory
measures.
future,
intend
investigate
bioaccumulation
MPs/NPs
Human Reproduction,
Journal Year:
2024,
Volume and Issue:
39(5), P. 936 - 954
Published: March 4, 2024
Abstract
STUDY
QUESTION
Is
there
a
cumulative
toxicity
of
disposables
used
in
IVF
procedures?
SUMMARY
ANSWER
A
may
be
detected
when
consumables
are
cumulatively,
while
no
is
the
same
and
tested
individually.
WHAT
IS
KNOWN
ALREADY
Many
components
items
laboratories
impair
human
embryonic
development.
Consequently,
it
necessary
to
screen
all
reagents
materials
which
could
contact
with
gametes
embryos.
Toxicity
tests,
such
as
mouse
embryo
assay
sperm
motility
(HSMA),
by
manufacturers
quality
control
tools
demonstrate
safety
their
products.
This
evaluation
currently
individually
performed
for
each
single
consumable.
However,
during
an
cycle,
several
devices
sequentially,
potentially
creating
exposure
chemical
contaminants,
not
consumables.
DESIGN,
SIZE,
DURATION
The
objective
this
observational
study
conducted
from
March
2021
October
2022
was
evaluate
HSMA
methodology
if
sequentially
used.
Fourteen
categories
routine
procedures
were
studied,
included
oocyte
collection
(cups,
condoms,
aspiration
needles),
manipulation
(flasks,
tubes,
tips,
pipettes,
transfer
catheters,
syringes,
gloves),
culture
(dishes),
storage
(straws).
PARTICIPANTS/MATERIALS,
SETTING,
METHODS
After
obtaining
patient
consent,
surplus
semen
assessed
having
normal
parameters
according
World
Health
Organization
2010
criteria
perform
HSMAs.
First,
consumable
Then,
associations
three,
four,
five
consumables,
previously
validated
non-toxic
individually,
analyzed.
HSMAs
three
times
ensure
reproducibility,
defined
threshold
index
(SMI)
below
0.85
at
least
two
tests.
MAIN
RESULTS
AND
THE
ROLE
OF
CHANCE
Thirty-six
references
first
across
53
lots.
Forty-nine
(92%)
demonstrated
compliance.
four
(8%)
revealed
toxicity:
one
lot
1
ml
lots
cups,
25
cm2
flasks.
These
excluded
procedures.
total
48
combinations
assessed,
involving
41
32
that
tested.
Among
evaluated
combinations,
17
out
(35%)
exhibited
SMI
tests
(n
=
8)
or
9).
Notably,
(18%)
three-consumable
associations,
16
(31%)
four-consumable
nine
15
(60%)
five-consumable
found
compliant.
did
originate
consumable,
because
only
pre-validated
but
had
origin.
risk
increased
number
association
(Cochran–Mantel–Haenszel
statistic,
P
0.013).
LIMITATIONS,
REASONS
FOR
CAUTION
high
proportion
non-compliant
can
attributed
directly
extreme
rigorous
extraction
conditions
employed
deviate
encountered
clinical
use.
Also,
(e.g.
duration,
concentrations,
protein
supplementation
medium)
influence
sensitivity
WIDER
IMPLICATIONS
FINDINGS
highlights
significance
performing
testing
on
before
introducing
them
into
practice.
Disposables
should
detect
immediate
toxicities
also
combination.
Our
results
advocate
rationalizing
procedure
re-evaluating
use
glass
FUNDING/COMPETING
INTEREST(S)
received
fundings
GCS
Ramsay
Santé
pour
l’Enseignement
et
la
Recherche
(Paris,
France)
Centre
de
Biologie
Médicale
BIOGROUP
(Le
Chesnay-Rocquencourt,
France).
authors
declare
they
have
conflict
interest
perceived
prejudicing
impartiality
reported
research.
TRIAL
REGISTRATION
NUMBER
N/A.
Sarhad Journal of Agriculture,
Journal Year:
2024,
Volume and Issue:
39(s1)
Published: Jan. 1, 2024
Microplastic
(MPs)
pollution
is
an
increasing
global
problem,
creating
deep
concerns
regarding
its
potential
impact
on
human
health.Numerous
experiments
have
been
conducted
living
organisms
to
investigate
the
dispersion
patterns
of
MPs.Furthermore,
extent
distribution
and
research
MPs
about
mice
still
needs
be
improved.This
study
aimed
determine
PET
(polyethylene
terephthalate)
mice's
weight,
feces,
appetite.Four
feed
experiments,
P0
(pellet
BR1),
P1
(potato
from
Pujon
Farm),
P2
mixed
300
µg
PET),
P3
600
were
investigated
in
this
research.PET
at
a
dose
had
worst
compared
others.There
changes
eating
performance,
body
feces
treatment
due
contained
them.Another
consequence
anticipated:
A
reduction
microbial
diversity
intestines
mice,
resulting
fall
both
weight
mice.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 11, 2024
Abstract
Nanoplastics
(NPs)
and
Microplastics
(MPs)
have
become
a
global
concern
in
recent
years.
However,
the
effects
of
NPs
MPs
on
female
reproductive
system
not
been
elucidated,
yet.
In
this
study,
we
aimed
to
establish
proper
vitro
exposure
protocol
investigate
possible
cytotoxic
human
endometrial
cells,
using
different
plastic
size
concentrations.
It
was
noted
that
smaller
plastics,
specifically
100
nm
1
µm
MPs,
exhibited
higher
propensity
for
cellular
uptake
compared
larger
counterparts
such
as
5
MPs.
These
particles
demonstrated
ability
induce
notable
morphological
changes
provoke
cell
death
at
concentrations
exceeding
µg/mL
over
24-hour
period.
Furthermore,
confirmed
accumulations
these
nucleus
cytoplasm
cells
confocal
microscopy
real-time
imaging
device.
A
significantly
rate
internalization
observed,
manifesting
discernible
correlation
between
plastics
degree
penetration
into
both
cytoplasm.
conclusion,
is
first
study
demonstrate
exposures
results
dynamic
within
stromal
leading
specific
Our
findings
imply
potential
adverse
impacts
fertility
health,
underscoring
need
further
research
elucidate
exact
underlying
molecular
mechanisms.
European Journal of Nutrition & Food Safety,
Journal Year:
2024,
Volume and Issue:
16(5), P. 11 - 31
Published: April 22, 2024
Plastics
released
into
the
environment
can
be
degraded
by
physical
erosion,
biodegradation,
photocatalytic
activity,
and
oxidation,
resulting
in
smaller
plastics
particles.
Microplastics
(MPs)
are
plastic
particles
relatively
than
5
mm
size.
Furthermore,
microplastics
with
particle
sizes
less
1000
or
100
nm
known
as
nano-plastics
(NPs).
The
presence
effect
of
MPs
NPs
human
body
has
not
been
adequately
studies,
thus
we
aim
to
explain
origins
adept,
carefully
explore
pathways
which
enter
system
highlight
impact
on
health.
Major
examples
include
Polyethylene
(PE),
polypropylene
(PP),
polyvinyl
chloride
(PVC),
polyamide
(PA),
polystyrene
(PS),
polyethylene
terephthalate
(PET),
Acrylonitrile-Butadiene-Styrene
(ABS),
polymethyl
methacrylate
(PMMA).
were
found
have
two
sources
(primary
secondary).
primary
materials
purposely
produced
suit
household
industrial
uses,
such
exfoliants
for
skin
care
products,
construction,
packaging
materials.
Secondary
originated
from
decomposition/degradation
large
products
over
time.
plants
(fruits
vegetables),
animals
(fish,
crab,
shrimp,
oysters,
mussels),
water
(taps,
sachet,
bottled
water),
salt,
sugar,
honey.
Plastics'
ecosystem
is
getting
increasingly
severe,
it
imperative
that
proper
attention
paid
this
issue.
vast
number
available
influence
lives
populace
each
geographic
area.
In
review
article,
identified
three
routes
through
gain
entrance
body:
oral
ingestion,
cutaneous
(skin
contact),
inhalation.
investigated
summarized
impacts
most
impacted
organs
included
lungs,
blood,
kidney,
brain,
ovary,
testes,
intestines.
review,
offered
a
viable
solution
includes
use
biodegradable
polymers,
increased
usage
eco-friendly
biotechnology
engineering
solutions,
implementation
regulatory
measures.
future,
intend
investigate
bioaccumulation
MPs/NPs
