Practical issues in geriatrics, Journal Year: 2024, Volume and Issue: unknown, P. 287 - 308
Published: Jan. 1, 2024
Language: Английский
Practical issues in geriatrics, Journal Year: 2024, Volume and Issue: unknown, P. 287 - 308
Published: Jan. 1, 2024
Language: Английский
Ageing Research Reviews, Journal Year: 2024, Volume and Issue: unknown, P. 102521 - 102521
Published: Sept. 1, 2024
Language: Английский
Citations
11Aging and Disease, Journal Year: 2024, Volume and Issue: unknown, P. 0 - 0
Published: Jan. 1, 2024
The study explores the intricate relationship between aging and development of noncommunicable diseases [NCDs], focusing on whether these are inevitable consequences or primarily driven by lifestyle factors. By examining epidemiological data, particularly from hunter-gatherer societies, highlights that many NCDs prevalent in modern populations rare suggesting a significant influence choices. It delves into mechanisms through which poor diet, smoking, other factors contribute to systemic physiological imbalances, characterized oxidative stress, insulin resistance hyperinsulinemia, dysregulation sympathetic nervous system, renin-angiotensin-aldosterone immune system. interplay this pattern individual such as genetic susceptibility, biological variability, epigenetic changes microbiome is proposed play crucial role range age-related NCDs. Modified biomolecules oxysterols advanced glycation end products also their development. Specific benign prostatic hyperplasia, Parkinson's disease, glaucoma osteoarthritis analyzed illustrate mechanisms. concludes while contributes risk NCDs, role, offering potential avenues for prevention intervention healthier living practices. One possible approach could be try restore balance, e.g. dietary measures [e.g. Mediterranean Okinawan diet Paleolithic diet] conjunction with [a combination of] pharmacological interventions changes.
Language: Английский
Citations
7The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 954, P. 176255 - 176255
Published: Sept. 12, 2024
Language: Английский
Citations
6Pathophysiology, Journal Year: 2024, Volume and Issue: 31(1), P. 1 - 17
Published: Jan. 5, 2024
Background: There is a considerable overlap between the clinical presentation of post-COVID-19 condition (PCC) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Many their common symptoms can be linked to dysregulation autonomic nervous system (dysautonomia). This study aimed objectively assess function in general group patients with PCC ME/CFS whose disease was not related COVID-19. We hypothesize that similarity chronic extends objective abnormalities. Methods: Synchronous recordings an electrocardiogram continuous dynamics blood pressure digital artery using Penaz method were obtained spiroarteriocardiorhythmography 34 diagnosed ME/CFS, whom onset associated COVID-19, 29 meeting definition 32 healthy controls. Heart rate variability (HRV) systolic diastolic (BPV) assessed at rest tests fixed respiratory rates. Indicators baroreflex regulation (baroreflex effectiveness index sensitivity) additionally determined rest. Results: The total power low-frequency high-frequency RR interval as well sensitivity significantly lower both compared Several diagnostic prediction models for developed based on HRV parameters. During slow breathing, parameters returned normal but patients. correlation analysis revealed close relationship HRV, BPV fatigue, HADS depressive/anxiety Conclusions: A similar pattern failure signs pathological acceleration age-dependent dysautonomia identified clinical, therapeutic implications these findings are discussed, light previously described relationships inflammation, vascular pathology, atherosclerotic cardiovascular dysfunction.
Language: Английский
Citations
5Mechanisms of Ageing and Development, Journal Year: 2024, Volume and Issue: 218, P. 111915 - 111915
Published: Feb. 13, 2024
Language: Английский
Citations
5Food Bioscience, Journal Year: 2024, Volume and Issue: 61, P. 104531 - 104531
Published: June 16, 2024
Language: Английский
Citations
4Tissue and Cell, Journal Year: 2025, Volume and Issue: 94, P. 102798 - 102798
Published: Feb. 13, 2025
Language: Английский
Citations
0Anesthesiology and Perioperative Science, Journal Year: 2025, Volume and Issue: 3(1)
Published: March 3, 2025
Language: Английский
Citations
0GeroScience, Journal Year: 2025, Volume and Issue: unknown
Published: March 12, 2025
Language: Английский
Citations
0DO - Deutsche Zeitschrift für Osteopathie, Journal Year: 2025, Volume and Issue: 23(02), P. 4 - 10
Published: March 1, 2025
Citations
0