Use, knowledge, attitudes and practices of formal and alternative medicine related to Covid-19 in the Ecuadorian population. DOI Creative Commons
César Paz‐y‐Miño, Paola Leone

Bionatura, Journal Year: 2022, Volume and Issue: 7(3), P. 1 - 9

Published: Sept. 15, 2022

The Covid-19 pandemic revealed a complex health problem for people and national systems. Faced with the initial ignorance of behavior SARS-COV-2 virus in populations, turned to relief alternative medicines. In Ecuador, use traditional or western medicine systematic approach conventional are evident realities. Our work aimed assess knowledge, attitudes practices regarding formal treat disease contagion. An open, personal confidential survey was carried out, 158 questions on general data, ethnicity, status, covid-19 tests, self-medication, medicinal plants other chemical products, antibiotics antiparasitics, among data. control patients, six months after finishing survey, they were asked about acceptance vaccine decision be vaccinated not. results 3,000 persons (50% female 50% male) show frequent medicine, even personnel university studies. study's conclusions reflect that choose any therapies have access mix treatments ones unproven toxic. Keywords: attitudes, practices, covid-19,

Language: Английский

Discovery of procyanidin condensed tannins of (−)-epicatechin from Kratom, Mitragyna speciosa, as virucidal agents against SARS-CoV-2 DOI
Sanya Sureram, Nopporn Chutiwitoonchai,

Tam Pooprasert

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 273, P. 133059 - 133059

Published: June 10, 2024

Language: Английский

Citations

10
Revisiting liquorice (Glycyrrhiza glabra L.) as anti-inflammatory, antivirals and immunomodulators: Potential pharmacological applications with mechanistic insight. DOI Creative Commons
Dheeraj Bisht,

Mohmmad Rashid,

Rajeshwar Kamal Kant Arya

et al.

Phytomedicine Plus, Journal Year: 2021, Volume and Issue: 2(1), P. 100206 - 100206

Published: Dec. 18, 2021

Glycyrrhiza glabra L. (G. glabra) commonly known as liquorice is one of the highly exploited and utilized medicinal plant world. Since ancient times considered an auspicious valuable traditional medicine across world for treatment various ailments.Several electronic online scientific databases such Science Direct, PubMed, Scopus, Scifinder, Google Scholar, books reports were assessed collecting information. All collected information was classified into different sections to meet objective paper.The database search yielded 3908 articles from countries. Out them ninety-eight published between 1956 2021 included, corresponding all detailed review on G. research anti-inflammatories, antivirals immunomodulatory through pre-clinical clinical models. From selective area studies its bioactive components it established (including molecular mechanisms) a suitable remedy per current requirement pandemic situation arise respiratory tract infection.Different relevant have been thoroughly reviewed gain insight utility constituents effects with special emphasized prevention COVID-19 infection possible mechanism action at level. Proposed directions future are also outlined encourage researchers find out mechanistic targets useful value added products in investigations.

Language: Английский

Citations

46
Zingiber officinale Roscoe: A comprehensive review of clinical properties DOI

Abdelhamid Bitari,

Imane Oualdi,

Rachid Touzani

et al.

Materials Today Proceedings, Journal Year: 2022, Volume and Issue: 72, P. 3757 - 3767

Published: Sept. 23, 2022

Language: Английский

Citations

17
Comparison between Gardenia jasminoides J. Ellis and Celosia cristata Linn. against Aggregatibacter actinomycetemcomitans: in vitro study ‎ DOI Creative Commons

Regina Widjaja,

Josephine Felicia,

Calvin Kurnia

et al.

Journal Of Advanced Pharmacy Education And Research, Journal Year: 2025, Volume and Issue: 15(1), P. 25 - 28

Published: Jan. 1, 2025

Aggregatibacter actinomycetemcomitans (Aa) is one of the causes periodontitis. Although severe periodontitis can be treated locally with chlorhexidine, prolonged usage medication have negative consequences. Consequently, to take over for other options are required. The purpose this study determine which plants a stronger antibacterial effect on Aa as well if Gardenia jasminoides J. Ellis (GJ) and Celosia cristata Linn. (CC) any at all. G

Language: Английский

Citations

0
Coping with COVID-19 using traditional medicine: perspectives from Joe Morolong, Northern Cape DOI Creative Commons
Masego Mirriam Motsumi, Livhuwani David Nemakonde

Health SA Gesondheid, Journal Year: 2025, Volume and Issue: 30

Published: Jan. 23, 2025

Background: Indigenous Knowledge Systems (IKS) have long been central to African communities, providing critical solutions health and disaster challenges. Traditional medicine, a significant component of IKS, continues play vital role in addressing needs, especially rural areas.Aim: This study sought gain insights on the use traditional medicine address COVID-19 pandemic five villages Joe Morolong Local Municipality, Northern Cape, South Africa.Setting: The was conducted Africa.Methods: By adopting qualitative research design with phenomenological approach, investigated participants’ lived experiences. Focus group discussions were 100 participants, conveniently sampled based availability. Data analysed using thematic analysis, uncovering key themes patterns..Results: Findings revealed that most participants their households relied treat symptoms. identified seven medicinal plants commonly used community detailed preparation administration methods. findings demonstrate essential fostering resilience during pandemic, complementing conventional healthcare services.Conclusion: underscores potential particularly biological hazards such as COVID-19.Contribution: highlights importance integrating practices into risk reduction strategies enhance vulnerable communities.

Language: Английский

Citations

0
Herbal medicine and non-hospital utilisation in Malaysia during the COVID-19 pandemic DOI Creative Commons

Ayushi Chander,

Terence Tan,

Rahela Zaman

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 22(1)

Published: March 17, 2025

Abstract Background COVID-19 is an infectious disease that led to over 3 million deaths globally during the pandemic. Herbal medicine (HM) has become popular pandemic; however, it unclear whether this reliance on HM affected conventional medical practices, including hospital utilisation. Objective The study’s objective was examine usage of from January 2021 December amidst pandemic and its association with non-hospital utilisation among Malaysians. Method A cross-sectional study conducted Malaysian population aged 18 years older. Findings 393 respondents diverse ethno-religious backgrounds (Malays 26.5%, Chinese 34.1%, Indians 34.6%, Indigenous peoples 3.3% others 15%) participated in study, 59% being females (n = 232). Most 286, 72.8%) reported fear visiting hospitals As a result, 51.4% 202) turned as alternative due availability 38, 18.8%) cost-effectiveness 36, 17.8%). consumers 133, 33.8%) preferred certified by Ministry Health (MOH), Malaysia purchased them pharmacy retailers 114, 29%). significant (P < 0.05) between consumption found. Nearly half 186, 47.3%) alleviated severity their symptoms. Logistic regression revealed users were 1.96 times more likely not utilise than non-HM user. Conclusion Overall, based personal knowledge significantly associated Fear one several contributing factors trend.

Language: Английский

Citations

0
Inhibitory effects of phytochemicals of spices on human monoamine oxidase B through molecular docking, molecular dynamics simulation, and DFT study DOI Creative Commons

Ram Lal Swagat Shrestha,

Prabhat Neupane, Sujan Dhital

et al.

Discover Chemistry., Journal Year: 2025, Volume and Issue: 2(1)

Published: March 18, 2025

Language: Английский

Citations

0
Research Progress in Pharmacological Activities and Applications of Cardiotonic Steroids DOI Creative Commons
Junwei Ren, Xinyuan Gao, Xi Guo

et al.

Frontiers in Pharmacology, Journal Year: 2022, Volume and Issue: 13

Published: June 2, 2022

Cardiotonic steroids (CTS) are a group of compounds existing in animals and plants. CTS commonly referred to cardiac glycosides (CGs) which composed sugar residues, unsaturated lactone rings steroid cores. Their traditional mechanism action is inhibit sodium-potassium ATPase strengthen the heart regulate rate, so it currently widely used treatment cardiovascular diseases such as failure tachyarrhythmia. It worth noticing that recent studies have found an avalanche inestimable values applications many fields anti-tumor, anti-virus, neuroprotection, immune regulation through multi-molecular mechanisms. Thus, pharmacological activities extensive prospects, would provide direction for new drug research development. Here, we review potential system other systems. We also suggestions clinical practical strategies CTS, diseases. Four main themes will be discussed, relation impact on 1) tumors, 2) viral infections, 3) nervous 4) immune-inflammation-related

Language: Английский

Citations

16
The Main Protease of SARS-CoV-2 as a Target for Phytochemicals against Coronavirus DOI Creative Commons
Shaza S. Issa, С. В. Сокорнова, Roman R. Zhidkin

et al.

Plants, Journal Year: 2022, Volume and Issue: 11(14), P. 1862 - 1862

Published: July 17, 2022

In late December 2019, the first cases of COVID-19 emerged as an outbreak in Wuhan, China that later spread vastly around world, evolving into a pandemic and one worst global health crises modern history. The causative agent was identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although several vaccines were authorized for emergency use, constantly emerging new viral mutants limited treatment options drastically highlighted need developing efficient this disease. One most important components to target purpose is main protease (Mpro). This enzyme excellent potential drug, it essential replication has no closely related homologues humans, making its inhibitors unlikely be toxic. Our review describes variety approaches could applied search among plant-derived compounds, including virtual silico screening (a data-driven approach), which structure-based or fragment-guided, classical approach high-throughput screening, antiviral activity cell-based assays. We will focus on classes compounds reported Mpro, phenols polyphenols, alkaloids, terpenoids.

Language: Английский

Citations

15
Wide identification of chemical constituents in fermented licorice and explore its efficacy of anti-neurodegeneration by combining quasi-targeted metabolomics and in-depth bioinformatics DOI Creative Commons
Xiaotong Wang, Ying Liu,

Nianxin Kang

et al.

Frontiers in Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: May 18, 2023

Licorice (Gan-Cao in Chinese) is one of the most famous herbal medicines around world. The fermentation probiotics and herbs can change chemical constituents significantly improve efficacy. However, it still unknown whether licorice fermented with would produce beneficial therapeutic effects. This study aimed to comprehensively analyze via quasi-targeted metabolomics, predict potential efficacy products diverse bioinformatic methods, further verify through vitro vivo experiments. As a result, 1,435 compounds were identified totally. Among them, 424 natural medicinal classified potentially important bioactivities, including 11 anthocyanins, 10 chalcones dihydrochalcones, 25 flavanones, 45 flavones flavonols, 117 flavonoids, 34 isoflavonoids, 21 phenols its derivatives, 20 phenylpropanoids polyketides, 96 terpenoids coumarins derivatives. Interestingly, prediction showed that targets some related neurodegeneration, oxidoreductase activity response stress. In tests verified had excellent effects DPPH clearance, anti-oxidation, anti-neurodegeneration, anti-stress. Thus, this provide reference method for research development licorice-related products.

Language: Английский

Citations

6