Archiv der Pharmazie,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 9, 2024
Abstract
As
the
main
active
compound
of
Glycyrrhiza
glabra
L.,
glabridin
(GLD)
has
been
shown
to
have
multiple
bioactivities,
whereas
clinical
application
GLD
is
restricted
by
its
low
water
solubility.
In
this
study,
was
encapsulated
into
a
sulfobutylether‐β‐cyclodextrin
(SBE‐β‐CD)‐based
inclusion
complex
(SBE‐β‐CD/GLD)
freeze‐drying
method.
The
materials
characterization,
antibacterial
activity,
stimulated
cellular
behavior
and
in
vivo
full‐thickness
diabetic
wound
healing
ability
hydrogels
were
assessed
analyzed.
successful
encapsulation
confirmed
ultraviolet
(UV)
visible
spectroscopy,
Fourier
transform
infrared
(FT‐IR),
X‐ray
diffractometer
(XRD),
scanning
electron
microscope
(SEM),
nuclear
magnetic
resonance
(NMR).
SBE‐β‐CD
as
an
excipient
significantly
enhances
solubility
GLD,
SBE‐β‐CD/GLD
showed
excellent
biocompatibility
on
human
vascular
endothelial
cells
(HUVECs)
erythrocytes.
exerted
pronounced
activity
Staphylococcus
aureus
Escherichia
coli
vitro.
markedly
enhanced
antioxidant
compared
with
free
GLD.
potently
accelerates
skin
defects
inhibiting
inflammation.
outcomes
suggest
that
could
be
used
promising
drug
delivery
system
for
Tzu Chi Medical Journal,
Journal Year:
2024,
Volume and Issue:
36(1), P. 1 - 22
Published: Jan. 1, 2024
Traditional
Chinese
medicine
(TCM)
has
gained
considerable
attention
over
the
past
few
years
for
its
multicomponent,
multitarget,
and
multi-pathway
approach
to
treating
different
diseases.
Studies
have
shown
that
TCMs
as
adjuvant
therapy
along
with
conventional
treatment
may
benefit
in
safely
various
disorders.
However,
investigations
on
finding
effective
herbal
combinations
are
ongoing.
A
novel
TCM
formula,
“Jing
Si
Herbal
Tea
(JSHT),”
been
reported
recently
their
health-promoting
effects
improving
overall
body
mental
health.
JSHT
is
a
combination
of
eight
herbs
recognized
pharmacopoeia
anti-viral,
anti-aging,
anti-cancer
properties
well
protective
against
cardiovascular,
metabolic,
neural,
digestive,
genitourinary
Thus,
better
understand
beneficial
ingredients
health,
this
review
intends
summarize
preclinical
clinical
studies
human
health
diseases,
possible
therapeutic
related
mode
actions
future
prospects
application
complementary
therapies.
Гербариум.,
Journal Year:
2025,
Volume and Issue:
2(1), P. 40 - 53
Published: Feb. 4, 2025
Introduction.
The
aim
of
the
review
is
to
summaries
information
on
medicinal
plants
used
in
prevention
respiratory
diseases.
Text.
According
Rosstat
data,
diseases
occupy
leading
positions
Russian
Federation
from
year
year.
For
treatment
acute
plant
medicines
are
used,
including
Glycyrrhiza
glabra
L.,
Mentha
spicata
Eucalyptus
globulus
Labill.,
Citrus
sinensis
(L.)
Pers.,
Cinnamomum
camphora
J.
Presl.
Conclusion.
given
extracts
have
a
long
experience
application
traditional
and
scientific
medicine,
contain
complex
biologically
active
substances
such
as
essential
oils,
saponins,
polyphenols
polysaccharides
with
antibacterial,
anti-inflammatory,
analgesic
other
effects
that
will
allow
therapy
tonsillopharyngitis,
relieve
symptoms
disease.
Life,
Journal Year:
2023,
Volume and Issue:
13(4), P. 874 - 874
Published: March 24, 2023
Inflammation
is
a
natural
protective
response
of
the
human
body
to
variety
hostile
agents
and
noxious
stimuli.
Standard
anti-inflammatory
therapy
includes
drugs
whose
usage
associated
with
number
side
effects.
Since
ancient
times,
compounds
have
been
used
for
treatment
inflammation.
Traditionally,
use
medicinal
plants
considered
safe,
inexpensive,
widely
acceptable.
In
Serbia,
traditional
medicine,
based
on
strong
belief
in
power
herbs,
widespread
form
treatment.
This
supported
by
fact
that
Serbia
classified
as
one
158
world
centers
biodiversity,
which
confirms
this
country
treasure
herbs.
Some
most
herbs
inflammations
various
causes
Serbian
tradition
are
yarrow,
common
agrimony,
couch
grass,
onion,
garlic,
marshmallow,
birch,
calendula,
liquorice,
walnut,
St.
John’s
wort,
chamomile,
peppermint,
white
willow,
sage,
many
others.
The
biological
activity
effect
selected
attributed
different
groups
secondary
biomolecules
such
flavonoids,
phenolic
acids,
sterols,
terpenoids,
sesquiterpenes,
tannins.
paper
provides
an
overview
reference
available
studies
examined
effect.
Plants
medicine
could
be
powerful
source
development
new
remedies.
Therefore
intensive
research
bioactive
potential
each
region
should
focus
scientists
around
world.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(18), P. 3866 - 3866
Published: Sept. 5, 2023
Background:
Renowned
since
ancient
times
for
its
medical
properties,
liquorice
is
nowadays
mainly
used
flavoring
candies
or
soft
drinks.
Continuous
intake
of
large
amounts
a
widely
known
cause
pseudo-hyperaldosteronism
leading
to
hypertension
and
hypokalemia.
These
manifestations
are
usually
mild,
although
in
some
cases
may
generate
life-threatening
complications,
i.e.,
arrhythmias,
muscle
paralysis,
rhabdomyolysis,
coma.
In
addition,
has
an
important
estrogenic-like
activity.
Methods:
We
summarized
the
current
knowledge
about
reviewed
104
case
reports
both
English
Italian
languages
from
inception
June
2023
concerning
complications
due
excess
intake.
Results:
contrast
most
published
data,
female
sex
old
age
do
not
appear
be
risk
factors.
However,
electrolyte
imbalance
(mainly
hypokalemia)
prevalent
features.
The
detection
glycyrrhetinic
acid
blood
very
uncommon,
diagnosis
essentially
based
on
accurate
history
taking.
Conclusions:
Although
there
significant
mortality
rate,
toxicity
often
requires
hospitalization
therefore
represents
health
concern.
Major
pharmaceutical
drug
regulatory
authorities
should
solicit
public
awareness
potentially
dangerous
effects
caused
by
excessive
use
liquorice.
Journal of Agricultural and Food Chemistry,
Journal Year:
2023,
Volume and Issue:
71(50), P. 20372 - 20385
Published: Dec. 6, 2023
Characterization
and
spatial
distribution
studies
of
the
metabolome
in
plants
are
crucial
for
revealing
physiology
developing
functional
foods.
Using
rhizome
Glycyrrhiza
uralensis
as
a
case,
we
integrated
desorption
electrospray
ionization-mass
spectrometry
imaging
(DESI-MSI)
high-resolution
liquid
chromatography/mass
approaches
aimed
at
characterizing
locating
both
small
molecules
macromolecular
polysaccharides.
Under
optimal
conditions,
21
flavonoids
12
triterpenoids
were
detected
characterized
different
tissues
another
19
components
exclusively
by
DESI-MSI.
Combined
with
hydrophilic
interaction
chromatography/ion
mobility-quadrupole
time-of-flight
mass
spectrometry,
eight
degrees
polymerization
oligosaccharides
(after
situ
acid
hydrolysis)
from
G.
uralensis.
Majority
these
metabolites
located
cortex,
phloem,
medulla,
which
lays
foundation
understanding
The
useful
information
can
benefit
sustainable
utilization
further
development
resource.
Chemical and Biological Technologies in Agriculture,
Journal Year:
2025,
Volume and Issue:
12(1)
Published: Jan. 14, 2025
This
study
aimed
to
investigate
the
effects
of
fermentation
on
physicochemical
properties
and
in
vitro
antioxidant
activities
Glycyrrhiza
leaf,
compare
structures
unfermented
(GLP)
fermented
(FGLP)
polysaccharides,
assess
their
growth-promoting
using
zebrafish
embryos.
The
results
showed
that
polysaccharide
content,
extract
yield,
reduced
sugar
content
leaf
increased
significantly
after
36
h
fermentation.
In
parallel,
assays
demonstrated
for
exhibited
strong
DPPH,
hydroxyl
radical
scavenging,
reducing
power.
Scanning
electron
microscope
infrared
spectroscopy
analyses
revealed
differences
surface
morphology
with
both
polysaccharides
being
acidic
containing
pyranose
rings
α-glycosidic
bonds.
molecular
weight
FGLP
was
lower
than
GLP,
molar
ratios
guluronic
acid,
amino
glucose,
glucuronic
xylose,
arabinose
were
increased.
model,
promoted
growth
development
embryos,
most
pronounced
effect
at
a
concentration
20
µg/mL
superior
protective
against
lipid
peroxidation
cell
death
induced
by
2,2′-azobis
(2-methylpropionamidine)
dihydrochloride.
findings
could
enhance
utilization
capacity.
These
opened
avenues
further
research
into
bioavailability
vivo
offered
valuable
insights
its
potential
as
natural
innovative
antioxidant.
Highlights
Journal of Natural Remedies,
Journal Year:
2025,
Volume and Issue:
unknown, P. 257 - 277
Published: Feb. 28, 2025
Mastitis,
characterized
by
mammary
gland
inflammation
due
to
microorganisms,
significantly
reduces
dairy
animal
productivity
up
70%.
Clinical
mastitis
prevalence
stands
at
11%,
with
sub-clinical
cases
a
staggering
77%,
highlighting
its
substantial
impact
on
milk
yield.
Given
the
escalating
concern
of
antibiotic
resistance,
exploring
alternative
therapies
for
treatment,
particularly
herbal
remedies
from
Ayurveda
and
Ethno-veterinary
practices,
is
imperative.
Literature
herbs
used
in
bovine
within
South
Asian
countries
was
meticulously
gathered
diverse
sources,
including
books
electronic
databases
like
Web
Science,
PubMed,
ScienceDirect,
Google
Scholar
domestic
literature.
A
comprehensive
review
identified
83
documented
anti-inflammatory
properties,
assessing
their
potential
treating
animals.
Constituents
such
as
flavonoids,
polyphenols,
terpenoids,
alkaloids,
vitamins,
minerals
were
scrutinised
effects.
Additionally,
formulations
mentioned
ancient
Indian
veterinary
Sanskrit
manuscript
‘Ashvavaidyakam’
have
been
revealed
verify
ability
mitigate
associated
future.
This
synthesizes
traditional
wisdom
contemporary
scientific
evidence
advocate
further
research
dialogue.
It
underscores
develop
effective
sustainable
control
strategies
practices.
Plant-based
are
highlighted
reduce
production
losses
costs,
thereby
proving
therapeutic
significance
farmers.
The
integration
knowledge
modern
findings
presents
promising
avenues
addressing
Embracing
offers
not
only
economic
benefits
but
also
contributes
sustainability
farming
practices
Asia.
Further
this
area
crucial
harness
full
management.
Major
Findings:
total
properties
treatment.
Active
constituents
terpenoids
alkaloids
exhibit
significant
potential.
Herbal
Ashvavaidyakam
offer
leads
management
