Research Square (Research Square),
Journal Year:
2022,
Volume and Issue:
unknown
Published: March 23, 2022
Abstract
The
development
of
transition
metal-catalyzed
β
-C−H
bond
activation
via
highly-strained
4-membered
metallacycles
has
been
a
formidable
task.
So
far,
only
scarce
examples
have
reported
to
undergo
metallacycles,
and
all
them
rely
on
precious
metals.
In
contrast,
earth-abundant
inexpensive
3d
still
remains
an
elusive
challenge.
Herein,
we
report
phosphine
oxide-ligated
Ni−Al
bimetallic
catalyst
activate
secondary
benzylic
C(sp
3
)−H
bonds
formamides
nickelacycles,
providing
series
α,β
-unsaturated
γ
-lactams
in
up
97%
yield.
European Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
2022(30)
Published: July 11, 2022
Abstract
The
dual‐catalysis
tactics
where
two
types
of
catalysts
are
connected
in
one
single
reaction
operation
highly
prized
the
novel
bond
constructions
that
difficult
or
unattainable
to
be
achieved
with
current
mono‐catalysis.
In
recent
years,
increased
emphasis
on
sustainable
catalytic
methods
more
economic
and
eco‐friendly
processes
has
shifted
focus
catalysis
earth‐abundant
transition
metals,
such
as
iron,
copper,
so
on.
As
most
inexpensive
environmentally
friendly
metals
earth,
research
development
based
either
iron
copper
flourishing,
iron‐copper
dual‐catalyzed
reactions
appeal
attention.
this
review,
we
mainly
cover
construction
C−C,
C−N,
C−B,
C−P,
C−S
C−Sn
bonds
enabled
by
published
literature
from
2011.
Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
136(39)
Published: July 5, 2024
Abstract
Herein,
we
describe
an
innovative
approach
to
the
asymmetric
electrochemical
α‐alkylation
of
aldehydes
facilitated
by
a
newly
designed
bifunctional
chiral
electrocatalyst.
The
highly
efficient
electrocatalyst
combines
aminocatalyst
with
redox
mediator.
It
plays
dual
role
as
mediator
for
electrooxidation,
while
simultaneously
providing
remarkable
induction
stereoselective
aldehydes.
Additionally,
this
novel
catalyst
exhibits
enhanced
catalytic
activity
and
excellent
control
comparable
conventional
systems.
As
result,
strategy
provides
new
avenue
versatile
electrochemistry.
electrooxidation
diverse
phenols
enables
C−H/C−H
oxidative
in
chemo‐
fashion.
Detailed
mechanistic
studies
experiments
cyclic
voltammetry
analysis
demonstrate
possible
reaction
pathways
origin
enantio‐induction.
European Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 2, 2024
Abstract
Ligands
play
a
key
role
in
asymmetric
transition‐metal
catalysis.
Among
reported
chiral
ligands,
readily
available
and
air‐stable
secondary
phosphine
oxide
ligands
are
unique
have
aroused
wide
interest
Ni−Al
bimetallic
catalysis,
since
they
can
act
as
bifunctional
to
ligate
two
metals
for
stronger
synergism,
greatly
enhancing
reactivity
selectivity.
Hence,
this
mini
review
we
will
focus
on
oxides
their
applications
Journal of Coordination Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 10
Published: Dec. 27, 2024
Bimetallic
catalysis
offers
a
unique
approach
to
diverse
bond
activation
chemistry,
complementing
the
more
widely
used
monometallic
catalysis.
In
this
context,
bimetallic
complexes
of
1,8-naphthyridine
motifs
have
been
synthesized
and
studied
mimic
active
sites
metalloenzymes
understand
their
role
in
C-C
formation
reactions.
Specifically,
dicopper(I)
with
naphthyridine
ligands
are
significant
interest
due
distinctive
binding
mode,
which
hinges
on
interaction
copper
available
molecular
orbitals.
These
naphthyridine-based
promising
as
catalysts
for
activating
terminal
alkynes
arenes,
enabling
several
strategic
functionalizations,
including
copper-catalyzed
azide-alkyne
coupling
This
mini-review
highlights
reactivity
selectivity
dicopper
importance
metal-metal
or
metal-ligand
cooperativity.
Research Square (Research Square),
Journal Year:
2022,
Volume and Issue:
unknown
Published: March 23, 2022
Abstract
The
development
of
transition
metal-catalyzed
β
-C−H
bond
activation
via
highly-strained
4-membered
metallacycles
has
been
a
formidable
task.
So
far,
only
scarce
examples
have
reported
to
undergo
metallacycles,
and
all
them
rely
on
precious
metals.
In
contrast,
earth-abundant
inexpensive
3d
still
remains
an
elusive
challenge.
Herein,
we
report
phosphine
oxide-ligated
Ni−Al
bimetallic
catalyst
activate
secondary
benzylic
C(sp
3
)−H
bonds
formamides
nickelacycles,
providing
series
α,β
-unsaturated
γ
-lactams
in
up
97%
yield.
