Biomolecules,
Journal Year:
2023,
Volume and Issue:
14(1), P. 59 - 59
Published: Dec. 31, 2023
Acute
pancreatitis
(AP)
is
a
common
acute
abdomen
disease
characterized
by
the
pathological
activation
of
digestive
enzymes
and
self-digestion
pancreatic
acinar
cells.
Secondary
infection
sepsis
are
independent
prognosticators
for
AP
progression
increased
mortality.
Accumulating
anatomical
epidemiological
evidence
suggests
that
dysbiosis
gut
microbiota
affects
etiology
severity
through
intestinal
barrier
disruption,
local
or
systemic
inflammatory
response,
bacterial
translocation,
regulatory
role
microbial
metabolites
in
patients
animal
models.
Recent
studies
discussing
interactions
between
pancreas
have
opened
new
scopes
AP,
therapeutic
interventions
target
bacteria
community
received
substantial
attention.
This
review
concentrates
on
alterations
its
roles
modulating
gut–pancreas
axis
AP.
The
potential
therapies
targeting
microbes
as
well
major
challenges
applying
those
explored.
We
expect
to
understand
diagnosis
treatment.
Foods,
Journal Year:
2023,
Volume and Issue:
12(5), P. 1095 - 1095
Published: March 4, 2023
Citrus
trees
are
among
the
most
abundant
fruit
in
world,
with
an
annual
production
of
around
124
million
tonnes.
Lemons
and
limes
significant
contributors,
producing
nearly
16
tonnes
per
year.
The
processing
consumption
citrus
fruits
generates
a
amount
waste,
including
peels,
pulp,
seeds,
pomace,
which
represents
about
50%
fresh
fruit.
limon
(C.
limon)
by-products
composed
amounts
bioactive
compounds,
such
as
phenolic
carotenoids,
vitamins,
essential
oils,
fibres,
give
them
nutritional
value
health
benefits
antimicrobial
antioxidant
properties.
These
by-products,
typically
discarded
waste
environment,
can
be
explored
to
produce
new
functional
ingredients,
desirable
approach
from
circular
economy
perspective.
present
review
systematically
summarizes
potential
high-biological-value
components
extracted
achieve
zero-waste
goal,
focusing
on
recovery
three
main
fractions:
dietary
C.
their
applications
food
preservation.
Critical Reviews in Food Science and Nutrition,
Journal Year:
2023,
Volume and Issue:
unknown, P. 1 - 15
Published: Dec. 14, 2023
The
gastrointestinal
immune
system
is
crucial
for
overall
health,
safeguarding
the
human
body
against
harmful
substances
and
pathogens.
One
key
player
in
this
defense
dietary
fiber
pectin,
which
supports
gut's
barrier
fosters
beneficial
gut
bacteria.
Pectin's
composition,
including
degree
of
methylation
(DM),
RG-I,
neutral
sugar
content,
influences
its
health
benefits.
This
review
assesses
how
pectin
composition
impacts
what
advantages
specific
chemistries
has
metabolic,
cardiovascular,
health.
We
delve
into
recent
findings
regarding
pectin's
interactions
with
system,
receptors
like
TLRs
galectin
3.
Pectin
shown
to
fortify
mucosal
epithelial
layers,
but
effects
are
structure
dependent.
Additionally,
we
explore
potential
strategies
enhancing
function.
Understanding
distinct
affect
vital
developing
preventive
therapeutic
solutions
conditions
related
microbiota
imbalances
issues.
Ultimately,
offers
insights
boost
barrier's
effectiveness,
fostering
better
by
using
pectins
diet.
Foods,
Journal Year:
2023,
Volume and Issue:
12(13), P. 2494 - 2494
Published: June 27, 2023
The
growing
interest
in
a
healthy
lifestyle
has
contributed
to
disseminating
perspectives
on
more
sustainable
natural
resource
management.
This
review
describes
promising
aspects
of
using
cacti
the
food
industry,
addressing
sustainable,
nutritional,
and
functional
plant’s
production.
Our
study
provides
an
overview
potential
for
industry
encourage
cultivation
underutilized
cactus
species
their
commercial
exploitation.
production
advantages
over
other
agricultural
practices
by
mitigating
damage
ecosystems
encouraging
migration
agriculture.
application
ingredients
development
been
broad,
whether
producing
breads,
jellies,
gums,
dyes,
probiotics,
postbiotic
paraprobiotic
foods.
However,
field
probiotic
foods,
future
research
should
focus
technologies
applied
processing
researching
interactions
between
probiotics
raw
materials
determine
functionality
bioactivity
products.
Journal of Agricultural and Food Chemistry,
Journal Year:
2023,
Volume and Issue:
71(4), P. 2160 - 2172
Published: Jan. 17, 2023
In
this
study,
the
fermentation
characteristics
of
high
rhamnogalacturonan
I
pectic
polysaccharides
(RGI)
and
free-radical
degraded
RGI
(DRGI)
were
evaluated
by
a
human
fecal
batch-fermentation
model,
their
structural
properties
also
investigated.
As
result,
Mw
decreased
from
246.8
to
11.6
kDa,
branches
broken
dramatically.
Fermentation
showed
that
faster
produced
more
acetate
propionate
than
DRGI.
Both
them
reduced
Firmicutes/Bacteroidetes
ratio
promoted
development
Bacteroides,
Bifidobacterium,
Lactobacillus,
bringing
benefits
gut
ecosystem.
However,
composition
metabolic
pathways
microbiota
in
DRGI
different.
Most
dominant
bacteria
(such
as
[Eubacterium]_eligens_group)
participated
carbohydrate
utilization,
leading
better
performance
glucolipid
metabolism
energy
metabolism.
This
work
elucidated
large
molecular
weight
matters
modulatory
effect
RGI-type
vitro.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: April 8, 2024
Abstract
The
human
gut
microbiome
establishes
and
matures
during
infancy,
dysregulation
at
this
stage
may
lead
to
pathologies
later
in
life.
We
conducted
a
multi-omics
study
comprising
three
generations
of
family
members
investigate
the
early
development
microbiota.
Fecal
samples
from
200
individuals,
including
infants
(0-12
months
old;
55%
females,
45%
males)
their
respective
mothers
grandmothers,
were
analyzed
using
two
independent
metabolomics
platforms
metagenomics.
For
metabolomics,
gas
chromatography
capillary
electrophoresis
coupled
mass
spectrometry
applied.
metagenomics,
both
16S
rRNA
gene
shotgun
sequencing
performed.
Here
we
show
that
greatly
vary
elders
fecal
microbiota
populations,
function,
metabolome.
Infants
have
less
diverse
than
adults
present
differences
several
metabolite
classes,
such
as
short-
branched-chain
fatty
acids,
which
are
associated
with
shifts
bacterial
populations.
These
findings
provide
innovative
biochemical
insights
into
shaping
within
same
generational
line
could
be
beneficial
improving
childhood
health
outcomes.
Carbohydrate Polymers,
Journal Year:
2024,
Volume and Issue:
334, P. 122007 - 122007
Published: March 5, 2024
Pectins
are
dietary
fibers
that
attributed
with
several
beneficial
immunomodulatory
effects.
Depending
on
the
degree
of
esterification
(DE),
pectins
can
be
classified
as
high
methoxyl
pectin
(HMP)
or
low
(LMP).
The
aim
this
study
was
to
investigate
effects
methyl-esterification
intestinal
microbiota
and
its
properties
in
naive
mice.
Supplementation
diet
LMP
HMP
induced
changes
composition
mice
toward
Bacteroides,
which
mainly
promoted
by
HMP.
Metabolome
analysis
stool
samples
from
pectin-fed
showed
a
different
effect
two
types
levels
short-chain
fatty
acids
bile
acids,
consistent
highly
efficient
vivo
fermentation
LMP.
Analysis
serum
antibody
significant
increase
IgG
IgA
both
pectins,
while
FACS
revealed
decrease
infiltrating
inflammatory
cells
lamina
propria
Our
structural
investigated
determine
fermentability,
microbial
composition,
metabolite
production,
modulation
immune
responses.
Consumption
preferentially
altered
gut
suppressed
pro-inflammatory
responses,
suggesting
role
diseases.
