A Review on Seaweeds and Seaweed-Derived Polysaccharides: Nutrition, Chemistry, Bioactivities, and Applications

Food Reviews International, Journal Year: 2023, Volume and Issue: 40(5), P. 1312 - 1347

Published: May 18, 2023

In recent studies, marine macroalgae (seaweeds) have been highlighted as excellent sources of acquiring many bioactive polymers and metabolites with vast chemical biological values, which has attracted increasing research interests in seaweeds. Among a diversity seaweed-derived constituents, polysaccharides affirmed to possess an extensive array bioactivities, such antioxidant, antimicrobial, anticarcinogenic, immune-enhancing anti-inflammatory activities. Due the exhibition these seaweed promised great application potential food, feed, pharmaceutical, nutraceutical, cosmeceutical industries. As discovered, bioactivities were mainly contributed by complex polymeric structural features compositions highly associated extraction methods. This study comprehensively reviewed current prospective applications seaweeds their from nutritional perspectives, further shedding light on insight into structure-bioactivity relationship polysaccharides.

Language: Английский

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Nutritional, bioactive compounds content, and antioxidant activity of brown seaweeds from the Red Sea

Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 10

Published: July 26, 2023

Brown seaweeds are excellent sources of bioactive molecules with a wide range pharmacological effects, whose content can vary depending on several factors, including the origin and environment in which algae grow.This study aimed to estimate 19 compounds regarding primary secondary metabolites eight brown macroalgal species from clean Egyptian Red Sea coast. A proximate analysis, pigment, phenolic compounds, vitamin contents were determined. In addition, energy antioxidant activity estimated explore potential application as functional foods encourage species' commercialization.Based chemical composition, Polycladia myrica was most valuable species, comparatively high protein 22.54%, lipid 5.21%, fucoxanthin 3.12 μg/g, β-carotene 0.55 mg/100 g, carbohydrate 45.2%. This also acts great source C, flavonoids, tannins, phenol total capacity.The selected indicated that its phenol, pigment powerful based structure-activity relationships. result verified by strong correlation statistical analysis at 95% confidence level. From worldwide perspective obtained results, these may be reinforced an essential line future foods.

Language: Английский

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Innovative Processing and Industrial Applications of Seaweed

Phycology, Journal Year: 2025, Volume and Issue: 5(1), P. 10 - 10

Published: March 3, 2025

Seaweed is a resilient macrophytic plant thriving in intertidal zones. These are rapidly gaining attention due to their autotrophic nourishment, rapid growth, and minimal land requirement for cultivation. used various food non-food sectors, thus possessing immense potential as valuable bioresource with high commercial value. However, utilizing seaweed comes challenges at processing levels, particularly cost-effective downstream processing. Hence, this review highlights the advancement biomass together its application food, nutraceuticals, pharmaceuticals, cosmetics, sectors. Additionally, advancements cultivation applications of agriculture biostimulant, biofuel production, packaging material also reviewed. Finally, addresses need technology intensification, public awareness, financial investment enhance commercialization integration seaweed-based products into bioeconomy. The contribute climate change mitigation circular economy underscored, calling further research development optimize multifaceted applications.

Language: Английский

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Marine Algal Polyphenols as Skin Protective Agents: Current Status and Future Prospectives

Marine Drugs, Journal Year: 2023, Volume and Issue: 21(5), P. 285 - 285

Published: April 30, 2023

The skin is the outermost anatomical barrier, which plays a vital role in maintenance of internal homeostasis and protection against physical, chemical, biological detractors. Direct contact with various stimuli leads to several physiological changes that are ultimately important for growth cosmetic industry. Due consequences using synthetic compounds skincare cosmeceutical-related industries, pharmaceutical scientific communities have recently shifted their focus natural ingredients. nutrient-rich value algae, some most interesting organisms marine ecosystems, has attracted attention. Secondary metabolites isolated from seaweeds potential candidates wide range economic applications, including food, pharmaceuticals, cosmetics. An increasing number studies focused on polyphenol owing promising activities oxidation, inflammation, allergies, cancers, melanogenesis, aging, wrinkles. This review summarizes evidence beneficial properties future perspectives macroalgae-derived polyphenolic advancing

Language: Английский

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Polyphenols in selected marine algae and aromatic herbs with antimicrobial properties: A comparative study

The Egyptian Journal of Aquatic Research, Journal Year: 2024, Volume and Issue: 50(1), P. 71 - 77

Published: Jan. 6, 2024

The increasing resistance of bacteria toward commercial antibiotics recommends offering various natural products as potent alternatives. In this study, polyphenols including flavonoids and phenolic compounds were detected in the sampled seaweeds: Corallina officinalis, Ulva lactuca, Pterocladia capillacea, abundant Egyptian marine environment, aromatic herbs: Ocimum basilicum, Mentha longifolia, Salvia market. Phenolics different concentrations seaweed herbs, where highest values recorded for cinnamic acid (0.0213 mg/g), followed by ellagic concentration (0.0152 mg/g) S. officinalis. addition, estimated 87.8258 Kaempferol O. basilicum. antibacterial activity algal herbal extracts was evaluated. As revealed, Staphylococcus aureus ATCC 25923 most affected strain all extracts. considerable against (i.e., 16 mm P. capillacea extract) Pseudomonas aeruginosa 9027 44 C. officinalis extract). also exhibited high (34–38 mm). These showed activities (34–40 crude extract then fractioned preparative TLC plates afforded three materials: 1, 2, 3, Rf = 0.44, 0.29, 0.11, respectively. spots scraped collected from 12 sheets to detect their same pathogens compared Ciprofloxacin antibiotic. However, spot 1 inhibition.

Language: Английский

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Purification and fractionation of phycobiliproteins from Arthrospira platensis and Corallina officinalis with evaluating their biological activities

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Aug. 31, 2023

Phycobiliproteins (PBPs) are a class of water-soluble pigments with variety biological functions that present in red macroalgae and cyanobacterial species. The crude forms phycocyanin (C-PC) from the blue green alga Arthrospira platensis allophycocyanin (APC) macroalga Corallina officinalis were extracted purified by ammonium sulphate precipitation, anion exchange chromatography, size exclusion chromatography methods, respectively. obtained C-PC APC A. C. 0.31 mg/mL 0.08 mg/mL, respectively, molecular masses "17.0 KDa 19.0 KDa" "15.0 17.0 corresponding to α β subunits, FT-IR was used characterize order look into their structures. Highly extracts (A620/A280 > 4.0) subtractions' PC3 PC4 tested for activities. plus fractions exhibited potent anti-oxidant different ratios using three techniques. PC1 showed high anti-inflammatory (75.99 74.55%) anti-arthritic (78.89 76.92%) activities platensis, respectively compared standard drugs (72.02 71.5%). methanolic water both species greater antibacterial efficacy against Gram +ve than -ve marine bacteria. Our study shed light on potential medical uses as natural substances foods drugs. Further investigations required explore diverse chemical natures distinct PBPs cyanobacteria algae because amino acid sequences vary among algal

Language: Английский

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Assessment of antioxidant and digestive enzyme inhibition by phyco-molecules isolated from marine brown alga Sargassum wightii

Food and Humanity, Journal Year: 2024, Volume and Issue: 2, P. 100226 - 100226

Published: Jan. 4, 2024

Language: Английский

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Trans-Chalcone (1–3-diphenyl-2-propen-1-one) as a Therapeutic Candidate in Joint Inflammation via Reduction of TNF-α, IL-1β, IL-6, and IL-17 in Rodents: An In Vivo Study by RT-PCR and ELISA analysis

ACS Omega, Journal Year: 2024, Volume and Issue: 9(20), P. 22123 - 22135

Published: May 12, 2024

Autoimmune disorders include vast and distinct illnesses are characterized by an immune system-mediated attack on the body's own tissues. Because of their ability to impact any portion body, clinical symptoms incredibly varied. The variations in normally linked with release activation vasoactive, chemotactic substances cytokines. Cytokines perform a multitude vital biological tasks, such as response control, inflammation, proliferation, tissue repair. reversal inflammatory cytokines leukocyte infiltration into inflamed natural compounds provides effective remedy for autoimmune diseases. Here, oral administration trans-chalcone (TC) 28 days was tested gradually increasing doses (30, 60, 120 mg/kg) complete Freund's adjuvant (CFA)-provoked joint stiffness rats. Paw edema, arthritic index, stiffness, thermal flexion pain, C-reactive protein, rheumatoid factor (RF) levels were determined check drug effectiveness chronic model. Molecular docking studies revealed strong binding affinity mediators TNF-α, IL-17, COX-2, iNOS; further, they quantified at mRNA level RT-PCR ELISA analysis. Oral TC significantly ameliorated paw thymus spleen indices, RF, mobility, stance treated animals. This therapeutic reduction expression proinflammatory IL-1β, IL-6, IL-17. findings reported research confirmed ameliorating pain prominently lowering

Language: Английский

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Chemical Composition, Antimicrobial Activity, and Molecular Docking of the Main Phytoconstituents from Three Rarely Investigated Marine Macroalgae

Natural Product Communications, Journal Year: 2024, Volume and Issue: 19(6)

Published: June 1, 2024

Objective: This study aimed to investigate the phytochemical and mineral compositions, antimicrobial activities, molecular docking of 3 abundant understudied seaweeds ( Cystoseira trinodis, Padina boryana, Turbinaria triquetra). Methods: Extraction was performed using absolute ethanol, chemical compositions were determined standard methods Association Official Analytical Chemists. Total phenolics flavonoids assessed Folin-Ciocalteu aluminum chloride methods, respectively. Chemical composition screened gas chromatography-mass spectrometry (GC-MS), activity evaluated a disc diffusion assay. In addition, analysis main compounds performed. Results: The samples had high ash, carbohydrate, fiber contents. results showed amount Na, K, Mg, Ca, Fe, with highest values for Ca. Trace elements such as Cu, Mn, Zn found in low amounts studied species. content total ranged from 15.54 ± 0.1 39.5 0.2 mg gallic acid equivalent/g. For flavonoid, it 3.4 0.3 1.5 rutin/g. GC-MS revealed 9 major compounds, mainly fatty acids, which have been reported activity. indicated higher impact extracts against bacteria Bacillus subtilis, Staphylococcus aureus, Escherichia coli Proteus vulgaris) than fungi Candida albicans Aspergillus fumigatus), stronger dose-dependent effect gram-positive B. subtilis S. aureus) gram-negative E. P. vulgaris). Molecular identified 1,2-benzenedicarboxylic mono(2-ethylhexyl) ester binding compound penicillin-binding protein 6, suggesting its potential Conclusion: These findings suggest that these seaweed species could serve promising sources functional foods properties, applications nutraceutical pharmaceutical fields.

Language: Английский

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Effects of Ultrasound-Assisted Treatment on Physicochemical Properties and Biological Activities of Polysaccharides from Sargassum

Foods, Journal Year: 2024, Volume and Issue: 13(23), P. 3941 - 3941

Published: Dec. 6, 2024

The aim of this study was to investigate the effect ultrasonic treatment on physicochemical properties and bioactivities polysaccharides from

Language: Английский

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