World of Medicine and Biology, Journal Year: 2022, Volume and Issue: 18(81), P. 218 - 218
Published: Jan. 1, 2022
Language: Английский
International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(5), P. 4840 - 4840
Published: March 2, 2023
Impaired levels of selenium (Se), zinc (Zn), copper (Cu), iron (Fe), manganese (Mn) and iodine (I) in the organism may adversely affect thyroid endocrine system. These trace elements play a role fight against oxidative stress as components enzymes. Oxidative–antioxidant imbalance is considered possible factor many pathological conditions, including various diseases. In available literature, there are few scientific studies showing direct correlation effect supplementation on slowing down or preventing occurrence diseases combination with improvement antioxidant profile, through action these antioxidants. Among studies, it has been shown that an increase lipid peroxidation decrease overall defense status occur during such cancer, Hashimoto’s thyroiditis dysthyroidism. which were supplemented, following observed: level malondialdehyde after Zn hypothyroidism reduction Se simultaneous total activity enzymes course autoimmune thyroiditis. This systematic review aimed to present current state knowledge about relationship between terms oxidoreductive homeostasis.
Language: Английский
Citations
29
Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14
Published: Aug. 30, 2023
Thyroid hormones and essential elements iodine (I), selenium (Se), iron (Fe), copper (Cu), zinc (Zn), calcium (Ca), magnesium (Mg), etc. play an important role in the work of many organs systems body, including immune system thyroid gland, a violation their supply can be cause pathological changes them. In pathology, interaction between (TG), minerals is disturbed. The review literature examines immunomodulatory TG, minerals, properties, participation pathogenesis autoimmune diseases (AITD). study relationship excess or deficiency AITD described. basis development - Hashimoto’s thyroiditis (HT), Graves’ disease (GD), ophthalmopathy (GO) loss tolerance to antigens peroxidase (TPO), thyroglobulin (Tg) thyroid-stimulating hormone receptor (TSH-R). Immune-mediated mechanisms production autoantibodies lymphocytic infiltration are involved AITD. Insufficiency regulatory T cells (Treg) B (Breg), imbalance Th17-lymphocytes Treg-lymphocytes, abnormal pro-inflammatory cytokines has significant influence on progression With AITD, balance oxidants antioxidants disturbed oxidative stress (OS) occurs. lack modern effective pharmacological therapy prompted us consider influence, possibilities immunocorrection pathogenetic factors using micro/macronutrients. order develop more treatment strategy, as well approaches prevention, critical analysis ways immunotherapeutic use dietary supplements I, Se, Zn, Mg other was carried out.
Language: Английский
Citations
24
Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)
Published: Feb. 20, 2024
Abstract Radioactive iodine isotopes especially 131 I are used for diagnosis and treatment of different types cancer diseases. Due to the leak radioactive into patient’s urine in turn, wastewater would be contaminated, so it is worth preparing a novel adsorption green material remove from efficiently. The removal 127 contaminants aqueous solution problem interest. Therefore, this work presents new study removing stable − solutions by using nano adsorbent (Nano ZnO/MWCNTs) which synthesized arc discharge method. It an economic method treating contaminated water undesired dissolved isotopes. optimal conditions maximum (5 mg/100 ml) as optimum dose with shacking (200 rpm) contact time (60 min), at (25 °C) acidic medium (pH = 5). After process, filtrated residual iodide ( ) measured UV wavelength absorbance 225 nm. capacity (15.25 mg/g); therefore prepared suitable polluted low concentrations. mechanism on surface multilayer physical according Freundlich isotherm model obeys Pseudo-first order kinetic model. According Temkin exothermic. efficiency Nano ZnO/MWCNTs has reached 97.23%, 89.75%, 64.78% case initial concentrations; 0.1843 ppm, 0.5014 ppm 1.0331 respectively. For radio radioactivity (20 µCi), was (10 min) 5) °C). filtration process done syringe filter pore size (450 nm) after 2 days equilibrate. (34.16%) first cycle percentage (65.86%). (94.76%) five cycles (5.24%). This last less than (42.15%) produces due natural decay during 10 days.
Language: Английский
Citations
5
Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 97, P. 102311 - 102311
Published: April 17, 2024
Language: Английский
Citations
5
Health Science Reports, Journal Year: 2025, Volume and Issue: 8(1)
Published: Jan. 1, 2025
ABSTRACT Background and Aims Globally thyroid disorders (TDs) are common health issues including in the Southeast Asian region. The purpose of this study was to ascertain prevalence Bangladeshi population, with a particular focus on frequency, etiology, comorbidity various diseases. Methods A cross‐sectional research design conducted southeastern part Bangladesh. Information regarding prior diagnosis current management TDs obtained through questionnaire. Results Of 300 respondents, 209 were female, 91 male. Females found be more predominant across all categories ( χ 2 = 17.738, p < 0.05). Furthermore, older age group (31–45 years) demonstrated higher frequency problems (OR: 1.320). Specifically, hyperthyroidism identified as most disorder, followed by hypothyroidism, euthyroidism. Hyperthyroidism less males (18.69%) compared females (43.06%), while hypothyroidism prevalent (46.15%) (27.75%). Multiple logistic regression analysis demonstrates that participants family history have significantly chance 2.991, CI: 1.480–6.044, 0.05) having than those without such history. Interestingly, studied population also exhibited rates comorbidities gastritis, diabetes, cardiovascular Conclusion According study's findings, it is advised concentrate educating Bangladeshis about problems, particularly female population. Moreover, healthcare professionals should check elderly patient's conditions consider possibility dysfunction can coexist other conditions.
Language: Английский
Citations
0
Journal of Lifestyle and SDGs Review, Journal Year: 2025, Volume and Issue: 5(1), P. e03802 - e03802
Published: Jan. 8, 2025
Objective: The study aims to determine the effect of different treatments on radical scavenging activity (RSA) and total phenolic compounds (TPC) rejected red yellow-fleshed peels rinds that were left field rot in Antique, Philippines. Method: Yellow-fleshed Sweet Gold (YFSG), red-fleshed 16 (RF16) Buffalo (RFBF) pre-treated with steam blanching (SB) calamansi (CAL) juice extract, untreated as control (UR). Half samples treated 8% NaCl. SB CAL oven-dried at 400C, while NaCl UR 400C 600C. Dried powdered for DPPH RSA TPC analysis. ONE-WAY analysis variance (ANOVA) Fisher’s least significant difference post-hoc was used analyze results. Results Discussion: best treatment increase YFSG came from CAL, RF16 600C, RFBF 400C. High values obtained There also seems be no correlation between high its most cultivars. Research Implications: This research serves foundational knowledge target specific activities per cultivar. It has a potential application replace synthetic food preservatives additives. Originality/Value: is first Philippines characterize watermelon cultivars convert it preservative additive. ensures continual measures reduce agricultural losses wastes, conversion value-added product.
Language: Английский
Citations
0
Frontiers in Veterinary Science, Journal Year: 2025, Volume and Issue: 12
Published: Feb. 26, 2025
Thyroid disease is an important condition to understand in elasmobranchs, with goiters being predominant. To identify dysfunction, measuring serum thyroid hormone levels a standard of practice for diagnosing most species. Although these have been reported elasmobranch literature, the testing methodology varied and values are not clinically useful aquarium In group aquarium-housed had persistently low or detectable otherwise healthy animals as well disease. The concern reliability results diagnose disease, prompted shift iodine proxy determine health. This study assesses compared stage elasmobranchs without dietary supplementation, efficacy using guide clinical decisions. Serum were lower than readable range curve both sharks rays; thus usually extrapolated. Including additional standards down limit sensitivity improved detection, however increasing sample volume tested was determined be factor obtaining measurable low-value samples. three groups southern stingrays (Hypanus americanus). Other species maintained aquaria used biological comparisons. Non-goiter, diseased reliably elevated (over baseline) hormones iodine; goiter cases, useful. Additionally, it found that cobalt also some states correlated positively levels. Current available may provide unless adjusted, severe. marker investigate Further, while identifiable hormones, straightforward substantial enough alone diagnosis.
Language: Английский
Citations
0
Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 282, P. 116754 - 116754
Published: July 23, 2024
Language: Английский
Citations
3
International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(8), P. 3708 - 3708
Published: April 14, 2025
Several strategies, including UV detection with a diode array detector (DAD), laser-induced fluorescence (LIF), derivatization reactions, the use of micelles in separation buffer, as well online preconcentration techniques based on pressure-assisted electrokinetic injection (PAEKI), and offline using solid-phase extraction (SPE) columns containing quaternary amine groups chloride counterion, were investigated for simultaneous signal amplification free thyroid hormones (THs) biological samples. Moreover, sensitive method quantification THs selected samples micellar capillary chromatography LIF (MEKC-LIF) was developed. The present (L-tyrosine, T2, T3, rT3, T4, DIT) successfully separated less than 10 min. analytes following procedure fluorescein isothiocyanate isomer I (FITC). A background electrolyte (BGE) composed 20 mM sodium tetraborate (Na2B4O7) dodecyl sulphate (SDS) employed. Key validation parameters such linearity, precision, limits (LOD), (LOQ) determined. PAEKI electrophoretic determination demonstrates significant potential monitoring these real urine due to its high sensitivity efficiency.
Language: Английский
Citations
0
Cancers, Journal Year: 2024, Volume and Issue: 16(9), P. 1646 - 1646
Published: April 25, 2024
Melatonin, primarily synthesized in the pineal gland, plays a crucial role regulating circadian rhythms and possesses significant antioxidative properties. By neutralizing free radicals reducing oxidative stress, melatonin emerges as promising agent for prevention therapy of many different disorders, including cancer. This paper reviews relationship between thyroid gland melatonin, presenting experimental evidence on protective effects this indoleamine against damage to macromolecules tissue caused by documented carcinogens (as classified International Agency Research Cancer, IARC) or potential carcinogens. Furthermore, possible influence cancer humans overall well-being patients are discussed. The article highlights melatonin’s essential maintaining health its contribution management strategies with other diseases.
Language: Английский
Citations
2