Plasmonic nanoparticle sensors: current progress, challenges, and future prospects
Nanoscale Horizons,
Journal Year:
2024,
Volume and Issue:
9(12), P. 2085 - 2166
Published: Jan. 1, 2024
This
comprehensive
review
summarizes
the
past,
present,
and
future
of
plasmonic
NP-based
sensors
in
terms
different
sensing
platforms,
chemical
biological
analytes,
expected
technologies.
Language: Английский
Aptamers and antibodies in optical biosensing
Discover Chemistry.,
Journal Year:
2025,
Volume and Issue:
2(1)
Published: Feb. 24, 2025
Language: Английский
Nano biosensors: Classification, electrochemistry, nanostructures, and optical properties
Results in Engineering,
Journal Year:
2024,
Volume and Issue:
unknown, P. 103428 - 103428
Published: Nov. 1, 2024
Language: Английский
Gold Nanoprobes for Robust Colorimetric Detection of Nucleic Acid Sequences Related to Disease Diagnostics
Nanomaterials,
Journal Year:
2024,
Volume and Issue:
14(22), P. 1833 - 1833
Published: Nov. 16, 2024
Gold
nanoparticles
(AuNPs)
are
highly
attractive
for
applications
in
the
field
of
biosensing,
particularly
colorimetric
nucleic
acid
detection.
Their
unique
optical
properties,
which
sensitive
to
changes
their
environment,
make
them
ideal
candidates
developing
simple,
rapid,
and
cost-effective
assays.
When
functionalized
with
oligonucleotides
(Au-nanoprobes),
they
can
undergo
aggregation
or
dispersion
presence
complementary
sequences,
leading
distinct
color
that
serve
as
a
visual
signal
Aggregation-based
assays
offer
significant
advantages
over
other
homogeneous
assays,
such
fluorescence-based
methods,
namely,
label-free
protocols,
rapid
interactions
solutions,
detection
by
naked
eye
using
low-cost
instruments.
Despite
promising
results,
application
Au-nanoprobe-based
complex
biological
matrices
faces
several
challenges.
The
most
related
colloidal
stability
oligonucleotide
functionalization
Au-nanoprobes
but
also
mode
type
method,
spacer,
oligo-AuNPs
ratio,
pH,
temperature,
ionic
strength
influence
Au-nanoprobe
thus
performance
assay.
This
review
elucidates
characteristics
determined
gold
(AuNPs)-based
detection,
how
sensitivity
specificity
These
assay
fundamental
low-cost,
robust
biomedical
sensors
perform
effectively
fluids.
Language: Английский
Engineered M13-Derived Bacteriophages Capable of Gold Nanoparticle Synthesis and Nanogold Manipulations
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(20), P. 11222 - 11222
Published: Oct. 18, 2024
For
years,
gold
nanoparticles
(AuNPs)
have
been
widely
used
in
medicine
and
industry.
Although
various
experimental
procedures
reported
for
their
preparation
manipulation,
none
of
them
is
optimal
all
purposes.
In
this
work,
we
engineered
the
N-terminus
pIII
minor
coat
protein
bacteriophage
(phage)
M13
to
expose
a
novel
HLYLNTASTHLG
peptide
that
effectively
specifically
binds
gold.
addition
binding
gold,
phage
could
synthesize
spherical
AuNPs
20
nm
other
sizes
depending
on
reaction
conditions,
aggregate
them,
precipitate
from
colloid,
as
revealed
by
transmission
electron
microscopy
(TEM),
atomic
force
(AFM),
scanning
(SEM),
well
ultraviolet–visible
(UV–vis)
Fourier-transform
infrared
(FTIR)
spectroscopic
methods.
We
demonstrated
exposing
foreign
selected
phage-displayed
library
may
serve
sustainable
molecular
factory
both
synthesis
subsequent
overnight
ions
at
room
temperature
neutral
pH
absence
strong
reducing
agents,
such
commonly
NaBH4.
Taken
together,
results
suggest
potential
applicability
new,
vitro-identified
gold-binding
diverse
biomimetic
manipulations.
Language: Английский