Environmental Health and Preventive Medicine,
Journal Year:
2023,
Volume and Issue:
28(0), P. 34 - 34
Published: Jan. 1, 2023
Due
to
the
continuous
spread
of
epidemic,
some
colleges
and
universities
have
implemented
a
campus
lockdown
management
policy
in
China.
In
context
lockdown,
this
study
aimed
explore
whether
anxiety
mediated
association
between
interpersonal
sensitivity
depression,
investigate
psychological
capital
moderated
indirect
or
direct
effect
mediation
model.A
total
12945
undergrad
students
were
recruited
China
from
April
10
19,
2022.
These
participants
asked
complete
online
questionnaires
measuring
sensitivity,
anxiety,
capital,
depression.
A
model
was
examined
by
using
PROCESS
macro
for
SPSS
25.0,
which
mediating
variable,
moderating
variable.Interpersonal
positively
associated
with
depression
among
Chinese
college
(r
=
0.47,
P
<
0.001).
Anxiety
partially
(indirect
2.31,
95%CI
[2.18,
2.44],
accounting
70%
effect).
Moreover,
interaction
on
(β
-0.04,
t
-17.36,
0.001)
0.002,
1.99,
0.05)
statistically
significant.The
current
explained
role
moderation
relation
The
findings
suggested
that
strict
monitoring
promoting
may
decrease
risk
during
lockdown.
Aging,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Feb. 2, 2024
Depression
is
a
neurological
disorder
that
profoundly
affects
human
physical
and
mental
health,
resulting
in
various
changes
the
central
nervous
system.
Despite
several
prominent
hypotheses,
such
as
monoaminergic
theory,
hypothalamic-pituitary-adrenal
(HPA)
axis
neuroinflammation,
neuroplasticity,
current
understanding
of
depression's
pathogenesis
remains
incomplete.
Importantly,
depression
gender-dimorphic
disorder,
with
women
exhibiting
higher
incidence
rates
than
men.
Given
estrogen's
pivotal
role
menstrual
cycle,
it
reasonable
to
postulate
its
fluctuating
levels
could
contribute
depression.
Estrogen
acts
by
binding
diversity
receptors,
which
are
widely
distributed
An
abundance
research
has
established
estrogen
receptors
play
crucial
depression,
spanning
treatment.
In
this
comprehensive
review,
we
provide
an
in-depth
analysis
fundamental
focus
on
neuroendocrinology,
neuroplasticity.
Furthermore,
discuss
potential
mechanisms
underlying
therapeutic
effects
treatment
may
pave
way
for
new
antidepressant
drug
development
alternative
options.
Brain Research Bulletin,
Journal Year:
2025,
Volume and Issue:
221, P. 111191 - 111191
Published: Jan. 7, 2025
Major
depressive
disorder
(MDD)
is
a
common
mental
with
chronic
tendencies
that
seriously
affect
regular
work,
life,
and
study.
However,
its
exact
pathogenesis
remains
unclear.
Patients
MDD
experience
systemic
localized
impairments
in
glucose
metabolism
throughout
the
disease
course,
disrupting
various
processes
such
as
uptake,
glycoprotein
transport,
glycolysis,
tricarboxylic
acid
cycle
(TCA),
oxidative
phosphorylation
(OXPHOS).
These
may
result
from
mechanisms
including
insulin
resistance,
hyperglycemia-induced
damage,
stress,
astrocyte
abnormalities,
mitochondrial
dysfunction,
leading
to
insufficient
energy
supply,
altered
synaptic
plasticity,
neuronal
cell
death,
functional
structural
damage
reward
networks.
mechanical
changes
contribute
of
severely
interfere
prognosis.
Herein,
we
summarized
impairment
pathophysiological
patients
MDD.
In
addition,
briefly
discussed
potential
pharmacological
interventions
for
alleviate
MDD,
glucagon-like
peptide-1
receptor
agonists,
metformin,
topical
insulin,
liraglutide,
pioglitazone,
encourage
development
new
therapeutics.
Journal of American College Health,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 12
Published: Jan. 16, 2024
Objective:
The
COVID-19
pandemic
has
led
to
greater
depression
and
anxiety
among
college
students.
Social
support
may
alleviate
this
risk.
We
examined
how
social
from
family,
friends,
romantic
partners
influence
internalizing
psychopathology
outcomes
associated
with
COVID-19-related
stressful
events.
Participants:
Participants
were
first-years
(N
=
425,
34.8%
Hispanic/Latinx,
74.9%
female)
enrolled
in
a
United
States
public
university.
Methods:
completed
an
online
survey
Fall
of
2020.
Linear
regression
models
associations
between
stressors,
support,
depressive
symptoms,
differences
White
Hispanic/Latinx
Results:
Reported
stressors
elevated
symptoms
higher
Family
friend
negatively
both
outcomes.
Partner
was
more
predictive
students
whereas
for
students'
anxiety.
Conclusions:
These
findings
demonstrate
the
importance
connectedness
during
pandemic.
Addictive Behaviors,
Journal Year:
2024,
Volume and Issue:
155, P. 108037 - 108037
Published: April 10, 2024
Since
the
COVID-19
outbreak,
people's
habits
changed
radically.
In
fact,
to
limit
spread
of
SARS-CoV-2,
governments
implemented
restrictive
measures
that
influenced
lives
individuals.
The
aim
this
systematic
review
is
analyze
impact
on
gambling
by
examining
three
different
outcomes:
frequency,
expenditure,
and
transition
among
possible
types
gambling.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Feb. 11, 2024
Abstract
The
COVID-19
pandemic
brought
about
a
major
public
health
concern
worldwide.
It
forced
many
countries
to
enforce
lockdowns,
leading
the
closure
of
higher
learning
institutions.
abrupt
shift
in
lifestyle
students
had
profound
impact
on
their
mental
health.
This
study
aims
determine
prevalence
and
factors
associated
with
conditions
among
university
Tanzania
during
pandemic.
A
sample
425
from
six
medical
universities
colleges
completed
an
online
survey
was
included
analysis.
questionnaire
consisted
validated
Depression,
Anxiety
Stress
Scale—21
Items
(DASS-21)
questions
(Cronbach’s
alpha
=
0.92)
assessing
presence
symptoms:
depression,
anxiety,
stress.
Multivariable
logistic
regression
models
were
fitted
explain
conditions.
P
-value
<
0.05
considered
statistically
significant
all
inferential
analyses.
median
age
(interquartile
range)
participants
24
(22–26).
28.94%,
54.12%,
15.06%
for
stress,
respectively,
while
having
any
condition
58.59%.
In
adjusted
model,
being
fourth
fifth
years
living
spouse
significantly
increased
odds
depression:
AOR
5.99
(1.31–27.47),
5.52
(1.18–25.81),
1.84
(1.08–3.15),
respectively.
Moreover,
studying
private
likelihood
anxiety:
2.35
(1.72–2.76),
2.32
(1.20–4.50),
stress
only
universities;
2.90
(1.60–5.27).
revealed
alarmingly
high
rates
findings
suggest
need
regular
checkups
regarding
status.
Additionally,
it
recommends
that
government
other
stakeholders
establish
services
within
effective
prevention
rising
burden
problems
similar
settings.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 29, 2024
Abstract
Background
This
study
protocol
specifies
the
primary
research
line
and
theoretical
framework
of
2023
Survey
Psychology
Behavior
on
Chinese
Population.
It
aims
to
establish
a
database
focused
psychology
behavior
among
residents
through
multicenter,
large-sample
cross-sectional
survey
provide
strong
data
support
for
development
in
related
fields.
will
track
public’s
physical
psychological
health
more
comprehensively
systematically.
Methods
The
was
conducted
from
20
June
31
August
2023,
using
stratified
quota
sampling
methods,
total
150
cities,
202
districts
counties,
390
townships/streets,
800
communities/villages
were
surveyed
(excluding
Taiwan,
which
selected
23
provinces,
five
autonomous
regions,
four
municipalities
directly
under
central
government
China).
questionnaires
distributed
face-to-face
by
trained
surveyors.
included
basic
information
about
individual,
personal
status,
family,
social
environment
individual
lives,
condition
scales,
behavioral
level
other
attitudes
towards
topical
issues.
Supervisors
quality
control
during
distribution
process
returned
questionnaires,
logically
checked
cleaned
analysis.
Discussion
Data
collection
has
been
finished,
scientific
outputs
based
this
promotion
strategies
China
globally.
In
aftermath
pandemic,
it
guide
policymakers
healthcare
organizations
improve
their
existing
policies
services
maximize
mental
population.
