Copper(ii)-based metal–organic framework delivery of calcium ascorbate for enhanced chemodynamic therapy via H2O2 self-supply and glutathione depletion DOI
Meng Zhang, Hongjin Xue, Jiaxin Yang

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(7), P. 1871 - 1882

Published: Jan. 1, 2024

A Cu/ZIF-8/Vc-Ca/HA nanosystem synchronously releases Fenton catalytic Cu 2+ and Vc-Ca to achieve improved chemodynamic therapy via H 2 O self-supply GSH depletion.

Language: Английский

Optimizing cancer therapy through metal organic frameworks-based nanozymes DOI

Qinxin Zhang,

Sai Chen,

Hongwei Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141409 - 141409

Published: Feb. 1, 2025

Language: Английский

Citations

0
Array of Manganese-Based Bimetallic Metal–Organic-Framework Nanozymes with Enhanced Oxidase-like Catalytic Activity Can Simultaneously Identify and Measure Antioxidants DOI

Oldouz Heidary,

Hossein Ashrafi, Morteza Akhond

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 26, 2025

Developing sensitive and highly active nanozymes for antioxidant analysis is of the utmost significance in medical diagnosis health monitoring due to their essential roles as free reactive oxygen species scavengers. Here, six metal-organic frameworks (MOFs)-based are developed a dual-mode absorbance/image colorimetric sensor array simultaneous discrimination determination various antioxidants with comparable structural or chemical properties. The catalysts exhibit wide range potent oxidase-like catalytic activities, verified by kinetic parameters, presence dispersed transition metallic bimetallic redox nodes. These efficiently catalyze oxidation colorless 3,3',5,5'-tetramethylbenzidine (TMB) blue TMBox, resulting noticeable absorption RGB color changes at 650 nm. Various demonstrate different reducing capabilities leading generation fingerprint-like spectral patterns. pattern recognition chemometrics methods including principal component (PCA) linear discriminant (LDA) represent well-separated clustering ascorbic acid, dopamine, uric cysteine, glutathione, thiocyanate, tannic gallic acid. assay provides detection (0.1-75 μM) limits low 30 nM. successfully discriminated concentrations, mixtures, interferences. Furthermore, sensor's applicability biologically relevant was validated urine plasma samples. Overall, MOF-based nanozyme offers promising platform discriminating determining potential applications.

Language: Английский

Citations

0
Exploration of cobalt-based colorimetric aptasensing of zearalenone in cereal products: Enhanced performance of Au/CoOOH nanozyme DOI Creative Commons
Qi Sun, Miaomiao Ma, Zhijuan Li

et al.

LWT, Journal Year: 2025, Volume and Issue: unknown, P. 117700 - 117700

Published: March 1, 2025

Language: Английский

Citations

0
Dual FeCo single-atom nanozymes with specific oxidase-like activity for sensitive detection of aflatoxin B1 DOI
Shaoyi Yu,

Pei Jia,

Shuqin Lin

et al.

Talanta, Journal Year: 2025, Volume and Issue: 294, P. 128256 - 128256

Published: May 4, 2025

Language: Английский

Citations

0
Copper(ii)-based metal–organic framework delivery of calcium ascorbate for enhanced chemodynamic therapy via H2O2 self-supply and glutathione depletion DOI
Meng Zhang, Hongjin Xue, Jiaxin Yang

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(7), P. 1871 - 1882

Published: Jan. 1, 2024

A Cu/ZIF-8/Vc-Ca/HA nanosystem synchronously releases Fenton catalytic Cu 2+ and Vc-Ca to achieve improved chemodynamic therapy via H 2 O self-supply GSH depletion.

Language: Английский

Citations

3