Clinical Nutrition,
Journal Year:
2024,
Volume and Issue:
43(7), P. 1736 - 1746
Published: May 29, 2024
Early
identification
of
people
at
risk
cancer-related
malnutrition,
low
muscle
mass
(LMM)
and
sarcopenia
is
crucial
to
mitigate
the
impact
adverse
outcomes.
This
study
investigated
factors
associated
with
LMM,
malnutrition
(probable-)
whether
these
varied
in
or
without
a
history
cancer.
Schweizerische medizinische Wochenschrift,
Journal Year:
2025,
Volume and Issue:
155(1), P. 4034 - 4034
Published: Jan. 17, 2025
Sarcopenia
is
a
progressive,
age-related
loss
of
muscle
mass,
strength
and
function.
Given
the
ageing
population
adverse
outcomes
associated
with
sarcopenia,
monitoring
its
epidemiology
particularly
important.
This
study
aimed
to
describe
sarcopenia
prevalence,
5-year
incidence
agreement
between
definitions
using
latest
operational
criteria
in
Swiss
postmenopausal
women.
Postmenopausal
women
from
last
5
years
CoLaus/OsteoLaus
prospective
population-based
cohort
were
included
based
on
complete
case
analysis
(April
2015
October
2022;
Lausanne,
Switzerland).
We
assessed
appendicular
lean
mass
via
Dual
X-ray
Absorptiometry
(GE
Lunar
iDXA),
handgrip
Jamar
Dynamometer
6-metre
gait
speed
at
multiple
visits.
was
defined
and/or
11
definitions,
including
that
European
Working
Group
Older
People
(EWGSOPII,
2019).
Prevalence
measured
as
number
rate
sarcopenic
cases
visit,
while
new
over
2.5
or
years.
A
total
930
included,
mean
(standard
deviation)
age
72.9
(6.9)
years,
BMI
25.7
(4.8)
kg/m2,
16.8
(2.5)
kg,
21.2
(5.5)
1.1
(0.2)
m/s.
prevalence
EWGSOPII
ranged
2.2%
5.7%,
other
varied
0.5%
13.4%.
The
rates
1.9%
4.7%.
increased
significantly
lowest
highest
tertiles
(Fisher's
exact
test,
p
<0.05)
for
most
definitions.
Agreement
predominantly
"none"
"minimal"
according
Cohen
Kappa
score.
highlights
an
increase
beginning
seventh
decade
life,
underscoring
accelerated
decline
health
age.
minimal
need
consensus,
which
would
improve
future
research
clinical
implementations.
Medicine,
Journal Year:
2025,
Volume and Issue:
104(8), P. e41635 - e41635
Published: Feb. 21, 2025
The
aim
of
this
study
is
to
compare
frailty
screening
tools
in
predicting
length
stay
(LOS)
older
patients
on
internal
medicine
inpatient
wards
transferred
from
the
emergency
department
(ED).
This
cross-sectional
retrospective
involving
186
subjects
aged
65
years
or
was
conducted
at
tertiary
hospital
ED
September
November
2023.
Frailty
defined
by
Clinical
Scale
(CFS),
identification
Seniors
At
Risk
Tool
and
Triage
Risk-Screening
(TRST).
Dependency
Katz
Index
Independence
activities
daily
living
(ADL)
Lawton
instrumental
ADL.
presence
according
CSF
TRST
associated
with
a
long
LOS
(coefficient
regression
β
=
0.2
P
<
.05).
But,
binary
logistic
analysis,
there
no
association
between
scales.
All
were
statistically
significant
predictors
for
disability
(
.001).
Our
findings
suggest
that,
among
evaluated,
CFS
may
be
most
robust
predictor
both
functional
dependency,
although
its
predictive
power
actual
remains
limited.
Future
studies
should
focus
refining
these
greater
accuracy
outcomes
examine
how
factors
such
as
polypharmacy
comorbidities
impact
outcomes.
Additionally,
longitudinal
are
needed
establish
causative
relationships
frailty,
LOS,
decline.
BACKGROUND
The
highly
academic
and
complex
nature
of
the
current
expert
consensus
on
sarcopenia
may
limit
public
awareness
understanding
this
disease.
OBJECTIVE
This
study
aims
to
develop
a
more
public-friendly
framework
for
future
guidelines
by
utilizing
model
that
incorporates
Google,
Chat
Generative
Pre-Trained
Transformer
4.0
(ChatGPT
4.0),
experts.
METHODS
first
step
human-centered
involved
identifying
most
popular
questions
using
“People
Also
Ask”
feature
Google.
In
second
step,
these
were
input
into
ChatGPT
generate
answers,
while
experts
reviewed
existing
provide
answers.
third
assessed
relevance
questions.
They
compared
analyzed
responses
from
reviews,
offering
suggestions
guidelines.
Finally,
results
analysis
used
as
prompts
RESULTS
We
scored
identified
9
was
inadequate
in
answering
consensus,
diagnostic
criteria
received
highest
emphasis,
scoring
25.5
points
(out
40
points),
followed
exercise
nutrition,
each
with
13
points.
contrast,
topics
such
prognosis
symptoms
addressed
less,
score
only
5.5
4.5,
respectively.
integrates
4.0,
human
experts,
Google
created
guidelines,
addressing
inadequately
covered
topics.
CONCLUSIONS
combines
has
great
potential
creating
accessible
clinical
CLINICALTRIAL
none
Journal of the American Geriatrics Society,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 15, 2025
ABSTRACT
Background
Frailty
is
a
syndrome
of
increased
vulnerability
to
health
stressors
that
associated
with
adverse
outcomes.
There
no
universally
accepted
method
measuring
frailty,
and
choosing
among
the
many
tools
often
confusing
for
clinicians.
Moreover,
acute
care
setting
presents
unique
challenges
operationalization
frailty
measurement,
implementation
into
daily
clinical
practice
has
been
variable.
The
objective
this
scoping
review
was
map
out
synthesize
how
being
measured
used
in
setting.
Methods
We
Arksey
O'Malley's
methodological
framework
reviews.
searched
MEDLINE,
EMBASE,
CINAHL,
SCOPUS,
Google
Scholar
primary
studies
assessing
from
inception
May
2023.
Results
Our
search
resulted
8834
articles,
which
2554
met
inclusion
criteria.
Most
articles
(75%)
were
published
last
5
years.
top
three
most
frequently
methods
measurement
Index
(41.0%),
Clinical
Scale
(23.3%),
Fried
Phenotype
(9.3%).
More
than
one
assessment
tool
11.2%
studies.
While
99.6%
evaluate
association
outcomes
or
validity
specific
tools,
only
0.4%
prospectively
adapt
healthcare
provision.
Conclusion
an
abundance
evidence
demonstrating
outcomes,
relatively
scarce
on
effect
adapting
care.
Future
research
focusing
prospective
management
needed.
Pituitary,
Journal Year:
2025,
Volume and Issue:
28(2)
Published: March 17, 2025
Abstract
Background
Frailty
is
a
state
of
physiological
vulnerability
rendering
patients
susceptible
to
adverse
perioperative
outcomes
after
neurosurgery.
The
effect
frailty
on
surgical
success
and
complication
rates
in
undergoing
transsphenoidal
pituitary
surgery
unclear.
Methods
A
systematic
review
the
literature
was
performed
accordance
with
PRISMA
statement.
Studies
that
utilised
validated
metrics
report
were
included.
Results
total
13
studies
included,
comprising
124,989
patients.
exclusively
assessed
cumulative
deficit
metrics,
however
there
significant
heterogeneity
patient
population,
definitions
assessment,
outcomes.
Frail
experienced
higher
medical
complications,
resulting
longer
hospital
stays,
greater
hospitalisation
costs,
unplanned
readmission,
more
discharges
destination
other
than
home,
increased
mortality.
These
directly
correlated
increasing
degrees
frailty.
Surgical
not
affected
by
frailty,
similar
biochemical
remission,
visual
recovery,
improvement
quality
life.
Conclusion
seen
minority
surgery,
but
an
important
indicator
risk.
assessment
should
be
used
as
reason
withhold
rather
predict
mitigate
complications
improve
surgery.
World Journal of Clinical Oncology,
Journal Year:
2025,
Volume and Issue:
16(4)
Published: March 26, 2025
With
the
global
population
aging,
care
of
elderly
cancer
patients
has
become
increasingly
complex
and
significant.
Comprehensive
geriatric
assessment
(CGA),
a
multidimensional
evaluation
tool,
been
widely
implemented
in
oncology
nursing
to
enhance
precision
treatment
decisions
improve
patient
outcomes.
This
review
examines
application
CGA
nursing,
drawing
on
literature
published
between
2010
2024
major
databases
using
keywords
such
as
“Comprehensive
Geriatric
Assessment”
“Oncology
Nursing”.
It
highlights
how
contributes
optimizing
selection,
monitoring
process,
improving
patients’
quality
life
long-term
provides
comprehensive
patients,
including
physical,
psychological,
social
aspects,
enabling
identification
high-risk
reducing
treatment-related
side
effects
complications.
also
offers
critical
foundation
for
developing
personalized
plans.
The
article
discusses
various
practical
examples
implementation
across
different
countries
regions,
multidisciplinary
collaborative
models
France,
United
States,
Australia,
demonstrating
CGA’s
flexible
diverse
healthcare
settings.
Although
significant
progress
made
applying
numerous
challenges
remain
its
implementation,
resource
limitations
insufficient
personnel
training.
Future
research
will
focus
integrating
with
emerging
technologies,
artificial
intelligence
medicine,
further
outcomes
patients.
By
summarizing
current
status
this
guidance
future
clinical
practice,
emphasizing
importance
advancing
meet
growing
demands
care.
Archives of Gerontology and Geriatrics,
Journal Year:
2025,
Volume and Issue:
unknown, P. 105835 - 105835
Published: March 1, 2025
This
study
evaluated
older
Australians
understanding,
awareness,
knowledge,
perceptions,
behaviours,
beliefs
and
attitudes
towards
muscle
health
sarcopenia,
barriers
exercise
nutrition
as
prevention
options.
A
national,
anonymous
41-question,
online
purpose-designed
survey
covering
the
concepts
outlined
in
objective
was
conducted
from
March-May
2024.
1261
adults
(≥50-y)
aged
50-94
years
participated.
Low
strength
poor
function
were
most
common
criteria
associated
with
health.
Knowledge
of
signs/symptoms,
risk
factors,
consequences,
effective
treatments
generally
high.
However,
there
uncertainty
about
unintentional
weight
loss
a
factor,
increased
for
infection/reduced
immunity
chronic
conditions
ineffective
options
(only
5-12
%
recognised
any
form
exercise,
aerobic
eating
more
fruits/vegetables
treatments).
Only
8.9
reported
their
doctor
had
discussed
but
82-95
would
act
if
they
received
information
on
factors
or
informed
at
Two-thirds
sarcopenia
serious
condition,
48
concerned
its
potential
impact,
despite
90
acknowledging
is
very
important
to
maintain.
around
half
believed
sufficient
knowledge
confidence
adopt
lifestyle
changes
reduce
risk,
motivation
leading
barrier
engaging
dietary
strategies
optimize
Older
recognize
importance
health,
understand
key
manage
it
identified
be
many
lack
improve
European Heart Journal,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 29, 2025
Abstract
As
life
expectancy
continues
to
increase
due
advancements
in
medical
technology,
public
health,
nutrition,
and
socioeconomic
progress,
the
population
of
older
adults
USA
Europe
is
rapidly
growing.
By
2050,
individuals
aged
65
are
projected
constitute
over
20%
US
29%
European
population,
leading
a
higher
prevalence
chronic
diseases,
including
cardiovascular
disease.
Cardiovascular
disease,
cause
death
USA,
poses
significant
challenges
healthy
ageing
by
contributing
accelerated
biological
development
geriatric
syndromes.
This
state-of-the-art
review
aims
(i)
define
for
patients
living
with
disease;
(ii)
compare
chronological
vs
as
it
pertains
(iii)
describe
impact
syndromes
provide
an
approach
management
prevention;
(iv)
address
gaps
knowledge
future
directions
potential
interventions
that
could
promote
ageing.