Are Dietary Patterns Relevant for Reducing the Risk of Fractures and Sarcopenia?

Current Osteoporosis Reports, Journal Year: 2025, Volume and Issue: 23(1)

Published: Jan. 23, 2025

Language: Английский

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Prevalence and incidence of sarcopenia in Swiss postmenopausal women: findings from the OsteoLaus Cohort

Schweizerische medizinische Wochenschrift, Journal Year: 2025, Volume and Issue: 155(1), P. 4034 - 4034

Published: Jan. 17, 2025

Sarcopenia is a progressive, age-related loss of muscle mass, strength and function. Given the ageing population adverse outcomes associated with sarcopenia, monitoring its epidemiology particularly important. This study aimed to describe sarcopenia prevalence, 5-year incidence agreement between definitions using latest operational criteria in Swiss postmenopausal women. Postmenopausal women from last 5 years CoLaus/OsteoLaus prospective population-based cohort were included based on complete case analysis (April 2015 October 2022; Lausanne, Switzerland). We assessed appendicular lean mass via Dual X-ray Absorptiometry (GE Lunar iDXA), handgrip Jamar Dynamometer 6-metre gait speed at multiple visits. was defined and/or 11 definitions, including that European Working Group Older People (EWGSOPII, 2019). Prevalence measured as number rate sarcopenic cases visit, while new over 2.5 or years. A total 930 included, mean (standard deviation) age 72.9 (6.9) years, BMI 25.7 (4.8) kg/m2, 16.8 (2.5) kg, 21.2 (5.5) 1.1 (0.2) m/s. prevalence EWGSOPII ranged 2.2% 5.7%, other varied 0.5% 13.4%. The rates 1.9% 4.7%. increased significantly lowest highest tertiles (Fisher's exact test, p <0.05) for most definitions. Agreement predominantly "none" "minimal" according Cohen Kappa score. highlights an increase beginning seventh decade life, underscoring accelerated decline health age. minimal need consensus, which would improve future research clinical implementations.

Language: Английский

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The challenge of applying the F-A-C-S pathway from EWGSOP2 for sarcopenia diagnosis in patients with chronic obstructive pulmonary disease: A diagnostic accuracy study

Rehabilitación, Journal Year: 2025, Volume and Issue: 59(1), P. 100879 - 100879

Published: Jan. 1, 2025

Language: Английский

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Comparison of frailty screening tools in predicting length of stay and disability in older patients on internal medicine inpatient wards transferred from the emergency department: A retrospective observational study

Medicine, Journal Year: 2025, Volume and Issue: 104(8), P. e41635 - e41635

Published: Feb. 21, 2025

The aim of this study is to compare frailty screening tools in predicting length stay (LOS) older patients on internal medicine inpatient wards transferred from the emergency department (ED). This cross-sectional retrospective involving 186 subjects aged 65 years or was conducted at tertiary hospital ED September November 2023. Frailty defined by Clinical Scale (CFS), identification Seniors At Risk Tool and Triage Risk-Screening (TRST). Dependency Katz Index Independence activities daily living (ADL) Lawton instrumental ADL. presence according CSF TRST associated with a long LOS (coefficient regression β = 0.2 P < .05). But, binary logistic analysis, there no association between scales. All were statistically significant predictors for disability ( .001). Our findings suggest that, among evaluated, CFS may be most robust predictor both functional dependency, although its predictive power actual remains limited. Future studies should focus refining these greater accuracy outcomes examine how factors such as polypharmacy comorbidities impact outcomes. Additionally, longitudinal are needed establish causative relationships frailty, LOS, decline.

Language: Английский

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Developing a Public-Friendly Sarcopenia Guideline Framework: A model integrating ChatGPT, human experts, and Google (Preprint)

Published: Feb. 26, 2025

The highly academic and complex nature of the current expert consensus on sarcopenia may limit public awareness understanding this disease. This study aims to develop a more public-friendly framework for future guidelines by utilizing model that incorporates Google, Chat Generative Pre-Trained Transformer 4.0 (ChatGPT 4.0), experts. first step human-centered involved identifying most popular questions using “People Also Ask” feature Google. In second step, these were input into ChatGPT generate answers, while experts reviewed existing provide answers. third assessed relevance questions. They compared analyzed responses from reviews, offering suggestions guidelines. Finally, results analysis used as prompts We scored identified 9 was inadequate in answering consensus, diagnostic criteria received highest emphasis, scoring 25.5 points (out 40 points), followed exercise nutrition, each with 13 points. contrast, topics such prognosis symptoms addressed less, score only 5.5 4.5, respectively. integrates 4.0, human experts, Google created guidelines, addressing inadequately covered topics. combines has great potential creating accessible clinical none

Language: Английский

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The Implementation of Frailty Assessment Tools in the Acute Care Setting: A Scoping Review

Journal of the American Geriatrics Society, Journal Year: 2025, Volume and Issue: unknown

Published: March 15, 2025

ABSTRACT Background Frailty is a syndrome of increased vulnerability to health stressors that associated with adverse outcomes. There no universally accepted method measuring frailty, and choosing among the many tools often confusing for clinicians. Moreover, acute care setting presents unique challenges operationalization frailty measurement, implementation into daily clinical practice has been variable. The objective this scoping review was map out synthesize how being measured used in setting. Methods We Arksey O'Malley's methodological framework reviews. searched MEDLINE, EMBASE, CINAHL, SCOPUS, Google Scholar primary studies assessing from inception May 2023. Results Our search resulted 8834 articles, which 2554 met inclusion criteria. Most articles (75%) were published last 5 years. top three most frequently methods measurement Index (41.0%), Clinical Scale (23.3%), Fried Phenotype (9.3%). More than one assessment tool 11.2% studies. While 99.6% evaluate association outcomes or validity specific tools, only 0.4% prospectively adapt healthcare provision. Conclusion an abundance evidence demonstrating outcomes, relatively scarce on effect adapting care. Future research focusing prospective management needed.

Language: Английский

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Frailty and pituitary surgery: a systematic review

Pituitary, Journal Year: 2025, Volume and Issue: 28(2)

Published: March 17, 2025

Abstract Background Frailty is a state of physiological vulnerability rendering patients susceptible to adverse perioperative outcomes after neurosurgery. The effect frailty on surgical success and complication rates in undergoing transsphenoidal pituitary surgery unclear. Methods A systematic review the literature was performed accordance with PRISMA statement. Studies that utilised validated metrics report were included. Results total 13 studies included, comprising 124,989 patients. exclusively assessed cumulative deficit metrics, however there significant heterogeneity patient population, definitions assessment, outcomes. Frail experienced higher medical complications, resulting longer hospital stays, greater hospitalisation costs, unplanned readmission, more discharges destination other than home, increased mortality. These directly correlated increasing degrees frailty. Surgical not affected by frailty, similar biochemical remission, visual recovery, improvement quality life. Conclusion seen minority surgery, but an important indicator risk. assessment should be used as reason withhold rather predict mitigate complications improve surgery.

Language: Английский

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Application of comprehensive geriatric assessment in oncology nursing: A literature review on optimizing treatment decisions and patient outcomes

World Journal of Clinical Oncology, Journal Year: 2025, Volume and Issue: 16(4)

Published: March 26, 2025

With the global population aging, care of elderly cancer patients has become increasingly complex and significant. Comprehensive geriatric assessment (CGA), a multidimensional evaluation tool, been widely implemented in oncology nursing to enhance precision treatment decisions improve patient outcomes. This review examines application CGA nursing, drawing on literature published between 2010 2024 major databases using keywords such as “Comprehensive Geriatric Assessment” “Oncology Nursing”. It highlights how contributes optimizing selection, monitoring process, improving patients’ quality life long-term provides comprehensive patients, including physical, psychological, social aspects, enabling identification high-risk reducing treatment-related side effects complications. also offers critical foundation for developing personalized plans. The article discusses various practical examples implementation across different countries regions, multidisciplinary collaborative models France, United States, Australia, demonstrating CGA’s flexible diverse healthcare settings. Although significant progress made applying numerous challenges remain its implementation, resource limitations insufficient personnel training. Future research will focus integrating with emerging technologies, artificial intelligence medicine, further outcomes patients. By summarizing current status this guidance future clinical practice, emphasizing importance advancing meet growing demands care.

Language: Английский

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Knowledge, awareness, behaviours, beliefs, attitudes, and perceptions of older Australians regarding muscle health and sarcopenia: A national survey

Archives of Gerontology and Geriatrics, Journal Year: 2025, Volume and Issue: unknown, P. 105835 - 105835

Published: March 1, 2025

This study evaluated older Australians understanding, awareness, knowledge, perceptions, behaviours, beliefs and attitudes towards muscle health sarcopenia, barriers exercise nutrition as prevention options. A national, anonymous 41-question, online purpose-designed survey covering the concepts outlined in objective was conducted from March-May 2024. 1261 adults (≥50-y) aged 50-94 years participated. Low strength poor function were most common criteria associated with health. Knowledge of signs/symptoms, risk factors, consequences, effective treatments generally high. However, there uncertainty about unintentional weight loss a factor, increased for infection/reduced immunity chronic conditions ineffective options (only 5-12 % recognised any form exercise, aerobic eating more fruits/vegetables treatments). Only 8.9 reported their doctor had discussed but 82-95 would act if they received information on factors or informed at Two-thirds sarcopenia serious condition, 48 concerned its potential impact, despite 90 acknowledging is very important to maintain. around half believed sufficient knowledge confidence adopt lifestyle changes reduce risk, motivation leading barrier engaging dietary strategies optimize Older recognize importance health, understand key manage it identified be many lack improve

Language: Английский

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Healthy ageing in older adults with cardiovascular disease

European Heart Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Abstract As life expectancy continues to increase due advancements in medical technology, public health, nutrition, and socioeconomic progress, the population of older adults USA Europe is rapidly growing. By 2050, individuals aged 65 are projected constitute over 20% US 29% European population, leading a higher prevalence chronic diseases, including cardiovascular disease. Cardiovascular disease, cause death USA, poses significant challenges healthy ageing by contributing accelerated biological development geriatric syndromes. This state-of-the-art review aims (i) define for patients living with disease; (ii) compare chronological vs as it pertains (iii) describe impact syndromes provide an approach management prevention; (iv) address gaps knowledge future directions potential interventions that could promote ageing.

Language: Английский

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